Metabotropic glutamate receptor 1 (GRM1)

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  1. SIB 1893, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 6266-99-5 EC Number: 635-306-9 PubChem CID: 5311432 Formula: C14H13N Molecular Weight: 195.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S286680
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    IUPAC Name
    2-methyl-6-[(E)-2-phenylethenyl]pyridine
    SMILES
    CC1=NC(=CC=C1)C=CC2=CC=CC=C2
    InChIKey
    SISOFUCTXZKSOQ-ZHACJKMWSA-N
    InChI
    1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
    Synonyms
    (E/Z)-SIB-1893 | 2-Methyl-6-styryl-pyridine(SIB-1893) | AKOS006279967 | BDBM86715 | HY-102094 | 2-Methyl-6-((E)-styry...
  2. Ibotenic acid, Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
    CAS: 2552-55-8 EC Number: 622-405-7 Formula: C5H6N2O4 Molecular Weight: 158.11
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A137136
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    IUPAC Name
    2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
    SMILES
    C1=C(ONC1=O)C(C(=O)O)N
    InChIKey
    IRJCBFDCFXCWGO-UHFFFAOYSA-N
    InChI
    1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
    Synonyms
    CHEBI:5854 | HMS3266E19 | Ibotenic acid, ~95%, solid | SMR001230640 | ( inverted question mark)-Ibotenic acid | HMS33...
  3. LY341495, Antagonist of mGlu 1 receptor;Antagonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 3 receptor;Antagonist of mGlu 4 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu
    CAS: 201943-63-7 Formula: C20H19NO5 Molecular Weight: 353.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: L125832
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    IUPAC Name
    (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
    InChIKey
    VLZBRVJVCCNPRJ-KPHUOKFYSA-N
    InChI
    1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/mshow more
    Synonyms
    (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid | LY341495 | LY-341495 | 1-chlo...
  4. PHCCC
    CAS: 179068-02-1 EC Number: 110-206-3 PubChem CID: 5866327 Formula: C17H14N2O3 Molecular Weight: 294.3
    In Stock Item #: P274879
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    IUPAC Name
    (7E)-7-hydroxyimino-N-phenyl-1,7a-dihydrocyclopropa[b]chromene-1a-carboxamide
    SMILES
    C1C2C1(OC3=CC=CC=C3C2=NO)C(=O)NC4=CC=CC=C4
    InChIKey
    FPXPIEZPAXSELW-CYVLTUHYSA-N
    InChI
    1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15-
    Synonyms
    AS-53727 | Benzo[b]cyclopropa[e]pyran-1a(1H)-carboxamide,7,7a-dihydro-7-(hydroxyimino)-N-phenyl-, (E)- (9CI) | HY-100...
  5. D-2-Aminoadipic acid
    CAS: 7620-28-2 Formula: C6H11NO4 Molecular Weight: 161.16
    In Stock Item #: A117161
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    IUPAC Name
    (2R)-2-aminohexanedioic acid
    SMILES
    C(CC(C(=O)O)N)CC(=O)O
    InChIKey
    OYIFNHCXNCRBQI-SCSAIBSYSA-N
    InChI
    1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m1/s1
    Synonyms
    Methyl3-isocyano-3-phenylpropionate | EN300-86337 | A-Aminoadipic acid | d-2-aminoadipate | AS-14204 | D-a-Aminoadipi...
  6. MPEP, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 96206-92-7 Formula: C14H11N Molecular Weight: 193.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M127959
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    IUPAC Name
    2-methyl-6-(2-phenylethynyl)pyridine
    SMILES
    CC1=NC(=CC=C1)C#CC2=CC=CC=C2
    InChIKey
    NEWKHUASLBMWRE-UHFFFAOYSA-N
    InChI
    1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
    Synonyms
    NCGC00025044-01 | NCGC00025044-02 | Pyridine, 6-methyl-2-(phenylethynyl)- | 2-Picoline, 6-phenylethynyl- | NCGC000156...
  7. D-Aspartic acid, Excitatory amino acid transporter 1;Excitatory amino acid transporter 2;Excitatory amino acid transporter 3;Excitatory amino acid transporter 4;Excitatory amino acid transporter 5;Agonist of GluN1;Agonist of GluN2A;Agonist of GluN2B;Agonist of GluN2C;Agon
    CAS: 1783-96-6 EC Number: 217-234-6 Formula: C4H7NO4 Molecular Weight: 133.10
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A105951
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    IUPAC Name
    (2R)-2-aminobutanedioic acid
    SMILES
    C(C(C(=O)O)N)C(=O)O
    InChIKey
    CKLJMWTZIZZHCS-UWTATZPHSA-N
    InChI
    1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
    Synonyms
    2,2'-methanediylbis(1H-benzimidazole) | 6-benzyloxy-1H-indole | C4H7NO4 | delta-aspartate | SR-01000597731 | C00402 |...
  8. D-Glutamic acid
    CAS: 6893-26-1 EC Number: 230-000-8 Formula: C5H9NO4 Molecular Weight: 147.13
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G100444
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    IUPAC Name
    (2R)-2-aminopentanedioic acid
    SMILES
    C(CC(=O)O)C(C(=O)O)N
    InChIKey
    WHUUTDBJXJRKMK-GSVOUGTGSA-N
    InChI
    1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
    Synonyms
    (r)-1-aminopropane-1,3-dicarboxylic acid | (2R)-2-aminopentanedioate | SR-01000597732 | CHEBI:53375 | GLUTAMIC ACID D...
  9. DL-2-Aminosuberic Acid
    CAS: 3054-07-7 PubChem CID: 77937 Formula: C8H15NO4 Molecular Weight: 189.21
    Out of Stock Item #: S161211
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    IUPAC Name
    2-aminooctanedioic acid
    SMILES
    C(CCC(C(=O)O)N)CCC(=O)O
    InChIKey
    YOFPFYYTUIARDI-UHFFFAOYSA-N
    InChI
    1S/C8H15NO4/c9-6(8(12)13)4-2-1-3-5-7(10)11/h6H,1-5,9H2,(H,10,11)(H,12,13)
    Synonyms
    2-aminooctanedioic acid | 2-Amino-octanedioic acid | DL-ALPHA-AMINOSUBERICACID | H-D-Asu-OH | AKOS015893070 | Hydrazi...
  10. UPF-523, Antagonist of mGlu 1 receptor
    CAS: 168560-79-0 Formula: C11H11NO4 Molecular Weight: 221.21
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A286905
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    IUPAC Name
    1-amino-2,3-dihydroindene-1,5-dicarboxylic acid
    SMILES
    C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N
    InChIKey
    LSTPKMWNRWCNLS-UHFFFAOYSA-N
    InChI
    1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
    Synonyms
    L000102 | NCGC00024861-04 | AIDA | FT-0643608 | Tox21_500119 | BDBM50030630 | DTXSID60870100 | AIDC | NCGC00024861-03...
  11. A 841720, Allosteric modulator of mGlu 1 receptor
    CAS: 869802-58-4 Formula: C17H21N5OS Molecular Weight: 343.45
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A345272
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    IUPAC Name
    5-(azepan-1-yl)-13-(dimethylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
    SMILES
    CN(C)C1=C2C3=C(C(=O)N(C=N3)N4CCCCCC4)SC2=NC=C1
    InChIKey
    GYWGXEGOXODOQU-UHFFFAOYSA-N
    InChI
    1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
    Synonyms
    BDBM50177080 | 9-dimethylamino-3-(N-hexamethyleneiminyl)-3H-5-thia-1,3,6-triazafluoren-4-one | 9-(DIMETHYLAMINO)-3-(H...
  12. Fenobam, Allosteric modulator of mGlu 5 receptor
    CAS: 57653-26-6 EC Number: 637-337-3 Formula: C11H11ClN4O2 Molecular Weight: 266.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F274825
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    IUPAC Name
    1-(3-chlorophenyl)-3-(1-methyl-4-oxoimidazolidin-2-ylidene)urea
    SMILES
    CN1CC(=O)NC1=NC(=O)NC2=CC(=CC=C2)Cl
    InChIKey
    DWPQODZAOSWNHB-UHFFFAOYSA-N
    InChI
    1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18)
    Synonyms
    MLS006011708 | [3H]fenobam | LP00842 | GTPL1433 | DWPQODZAOSWNHB-UHFFFAOYSA-N | Fenobam | NCGC00092384-04 | FT-063070...
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