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Metabotropic glutamate receptor 4 (GRM4)

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  1. SIB 1893, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
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    SIB 1893, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 6266-99-5 EC Number: 635-306-9 PubChem CID: 5311432 Formula: C14H13N Molecular Weight: 195.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S286680
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    IUPAC Name
    2-methyl-6-[(E)-2-phenylethenyl]pyridine
    SMILES
    CC1=NC(=CC=C1)C=CC2=CC=CC=C2
    InChIKey
    SISOFUCTXZKSOQ-ZHACJKMWSA-N
    InChI
    1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
    Synonyms
    (E/Z)-SIB-1893 | 2-Methyl-6-styryl-pyridine(SIB-1893) | AKOS006279967 | BDBM86715 | HY-102094 | 2-Methyl-6-((E)-styry...
  2. Ibotenic acid, Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
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    Ibotenic acid, Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
    CAS: 2552-55-8 EC Number: 622-405-7 Formula: C5H6N2O4 Molecular Weight: 158.11
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A137136
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    IUPAC Name
    2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
    SMILES
    C1=C(ONC1=O)C(C(=O)O)N
    InChIKey
    IRJCBFDCFXCWGO-UHFFFAOYSA-N
    InChI
    1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
    Synonyms
    CHEBI:5854 | HMS3266E19 | Ibotenic acid, ~95%, solid | SMR001230640 | ( inverted question mark)-Ibotenic acid | HMS33...
  3. VU 0361737, Allosteric modulator of mGlu 4 receptor
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    VU 0361737, Allosteric modulator of mGlu 4 receptor
    CAS: 1161205-04-4 EC Number: 802-357-5 PubChem CID: 44191096 Formula: C13H11ClN2O2 Molecular Weight: 262.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: V129527
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    IUPAC Name
    N-(4-chloro-3-methoxyphenyl)pyridine-2-carboxamide
    SMILES
    COC1=C(C=CC(=C1)NC(=O)C2=CC=CC=N2)Cl
    InChIKey
    ARYUXFNGXHNNDM-UHFFFAOYSA-N
    InChI
    1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
    Synonyms
    AC-32871 | VU 0361737 | VU0361737 | VU-0361737 | J-003384 | AKOS024457762 | BCP06488 | Benzo-1,4-quinone dioxime # | ...
  4. VU 0364770, Allosteric modulator of mGlu 4 receptor
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    VU 0364770, Allosteric modulator of mGlu 4 receptor
    CAS: 61350-00-3 EC Number: 111-965-3 PubChem CID: 836002 Formula: C12H9ClN2O Molecular Weight: 232.67
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: V129525
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    IUPAC Name
    N-(3-chlorophenyl)pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
    InChIKey
    SUYUTNCKIOLMAJ-UHFFFAOYSA-N
    InChI
    1S/C12H9ClN2O/c13-9-4-3-5-10(8-9)15-12(16)11-6-1-2-7-14-11/h1-8H,(H,15,16)
    Synonyms
    HY-100588 | HMS3884L20 | VU 0364770 | N-(3-chloro-phenyl)-pyridine-2-carboxamide | N-(3-chlorophenyl)pyridine-2-carbo...
  5. VU 0422288 - Moligand™, ≥98%(HPLC) CAS No(1630936-95-6) by Aladdin Scientific
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    VU 0422288, Allosteric modulator of mGlu 8 receptor
    CAS: 1630936-95-6 PubChem CID: 73058507 Formula: C17H11Cl2N3O2 Molecular Weight: 360.19
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: V287914
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    IUPAC Name
    N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl
    InChIKey
    MZRLPXFGQKQHST-UHFFFAOYSA-N
    InChI
    1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23)
    Synonyms
    ML 396 | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide | ML396 | N-(3-Chloro-4-((5-chloropyr...
  6. VU 0364439
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    VU 0364439
    CAS: 1246086-78-1 PubChem CID: 46934289 Formula: C18H13Cl2N3O3S Molecular Weight: 422.29
    ≥98%
    In Stock Item #: V129537
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    IUPAC Name
    N-[3-chloro-4-[(2-chlorophenyl)sulfamoyl]phenyl]pyridine-2-carboxamide
    SMILES
    C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl
    InChIKey
    IXHCGJXBIHHIEF-UHFFFAOYSA-N
    InChI
    1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24)
    Synonyms
    VU0364439 | VU-0364439 | AC-32760 | EX-A152 | Tox21_500841 | HMS3886H04 | CCG-268907 | SB19523 | SW219845-1 | N-[3-Ch...
  7. VU 6005649
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    VU 6005649
    CAS: 2137047-43-7 PubChem CID: 131954513 Formula: C16H12F5N3O Molecular Weight: 357.28
    ≥98%(HPLC)
    In Stock Item #: V287717
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    IUPAC Name
    3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    SMILES
    CC1=NC2=C(C(=NN2C(=C1)C(F)(F)F)C)C3=C(C(=C(C=C3)OC)F)F
    InChIKey
    NYBZCKAQIIPSDS-UHFFFAOYSA-N
    InChI
    1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3
    Synonyms
    3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
  8. L-O-Phosphoserine（L-SOP）, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
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    L-O-Phosphoserine（L-SOP）, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 407-41-0 EC Number: 206-986-0 Formula: C3H8NO6P Molecular Weight: 185.07
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(T)
    In Stock Item #: S161191
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    IUPAC Name
    (2S)-2-amino-3-phosphonooxypropanoic acid
    SMILES
    C(C(C(=O)O)N)OP(=O)(O)O
    InChIKey
    BZQFBWGGLXLEPQ-REOHCLBHSA-N
    InChI
    1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
    Synonyms
    L-SOP | CAS-407-41-0 | H-Ser(PO3H2)-OH | Phosphatidalserine | A873241 | CCG-204968 | NCGC00261571-01 | s5137 | (2S)-2...
  9. AIDA - ≥98%(HPLC), used for , CAS No. 168560-79-0, by Aladdin Scientific
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    UPF-523, Antagonist of mGlu 1 receptor
    CAS: 168560-79-0 Formula: C11H11NO4 Molecular Weight: 221.21
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A286905
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    IUPAC Name
    1-amino-2,3-dihydroindene-1,5-dicarboxylic acid
    SMILES
    C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N
    InChIKey
    LSTPKMWNRWCNLS-UHFFFAOYSA-N
    InChI
    1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
    Synonyms
    L000102 | NCGC00024861-04 | AIDA | FT-0643608 | Tox21_500119 | BDBM50030630 | DTXSID60870100 | AIDC | NCGC00024861-03...
  10. TC-N 22A - Moligand™, ≥98%(HPLC) CAS No(1314140-00-5) by Aladdin Scientific
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    TC-N 22A, Allosteric modulator of mGlu 4 receptor
    CAS: 1314140-00-5 PubChem CID: 46836562 Formula: C14H13N5S Molecular Weight: 283.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: T288621
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    IUPAC Name
    N-pyridin-2-yl-5-thia-3,11,12-triazatricyclo[8.3.0.02,6]trideca-1(10),2(6),3,12-tetraen-4-amine
    SMILES
    C1CC2=C(C=NN2)C3=C(C1)SC(=N3)NC4=CC=CC=N4
    InChIKey
    DBISXWCOHGUFSF-UHFFFAOYSA-N
    InChI
    1S/C14H13N5S/c1-2-7-15-12(6-1)17-14-18-13-9-8-16-19-10(9)4-3-5-11(13)20-14/h1-2,6-8H,3-5H2,(H,16,19)(H,15,17,18)
    Synonyms
    (Z)-N-(5,6-dihydropyrazolo[3',4':6,7]cyclohepta[1,2-d]thiazol-2(1H,4H,8H)-ylidene)pyridin-2-amine | 4,5,6,8-Tetrahydr...
  11. VU 0155041
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    VU 0155041
    CAS: 1093757-42-6 PubChem CID: 888023 Formula: C14H15Cl2NO3 Molecular Weight: 316.18
    ≥99%(HPLC)
    In Stock Item #: V287383
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    IUPAC Name
    (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
    SMILES
    C1CCC(C(C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)O
    InChIKey
    VSMUYYFJVFSVCA-NWDGAFQWSA-N
    InChI
    1S/C14H15Cl2NO3/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20)/t11-,12+/m0/s1
    Synonyms
    cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid | (1R,2S)-2-((3,5-dichlorophenyl)carbamoyl)cycl...
  12. TCN 238, Allosteric modulator of mGlu 4 receptor
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    TCN 238, Allosteric modulator of mGlu 4 receptor
    CAS: 125404-04-8 PubChem CID: 46911068 Formula: C12H11N3 Molecular Weight: 197.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: T287796
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    IUPAC Name
    4-[(E)-2-phenylethenyl]pyrimidin-2-amine
    SMILES
    C1=CC=C(C=C1)C=CC2=NC(=NC=C2)N
    InChIKey
    LNUXNUNUGIHCPA-VOTSOKGWSA-N
    InChI
    1S/C12H11N3/c13-12-14-9-8-11(15-12)7-6-10-4-2-1-3-5-10/h1-9H,(H2,13,14,15)/b7-6+
    Synonyms
    BDBM50323546 | AKOS000278717 | MS-23068 | 4-[(1E)-2-phenylethenyl]pyrimidin-2-amine | GTPL6235 | Lu AF32615 | TCN 238...
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