Metabotropic glutamate receptor 5 (GRM5)

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  1. L-CCG-l, Agonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 4 receptor;Agonist of mGlu 5 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 117857-93-9 Formula: C6H9NO4 Molecular Weight: 159.14
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    Out of Stock Item #: L287585
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    IUPAC Name
    (1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(=O)O)C(C(=O)O)N
    InChIKey
    GZOVEPYOCJWRFC-HZLVTQRSSA-N
    InChI
    1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1
    Synonyms
    AM85789 | L-CCG I | NCGC00024541-02 | SCHEMBL664330 | 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-C...
  2. SIB 1893, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 6266-99-5 EC Number: 635-306-9 PubChem CID: 5311432 Formula: C14H13N Molecular Weight: 195.26
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S286680
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    IUPAC Name
    2-methyl-6-[(E)-2-phenylethenyl]pyridine
    SMILES
    CC1=NC(=CC=C1)C=CC2=CC=CC=C2
    InChIKey
    SISOFUCTXZKSOQ-ZHACJKMWSA-N
    InChI
    1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+
    Synonyms
    (E/Z)-SIB-1893 | 2-Methyl-6-styryl-pyridine(SIB-1893) | AKOS006279967 | BDBM86715 | HY-102094 | 2-Methyl-6-((E)-styry...
  3. LSN2463359, Allosteric modulator of mGlu 5 receptor
    CAS: 1401031-52-4 EC Number: 802-759-0 Formula: C16H15N3O Molecular Weight: 265.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L167188
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    IUPAC Name
    N-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide
    SMILES
    CC(C)NC(=O)C1=NC=C(C=C1)C#CC2=CC=NC=C2
    InChIKey
    STAFRSGTRKNXHF-UHFFFAOYSA-N
    InChI
    1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20)
    Synonyms
    BGC03152 | GTPL6394 | 2-Pyridinecarboxamide, N-(1-methylethyl)-5-[2-(4-pyridinyl)ethynyl]- | N-Isopropyl-5-(pyridin-4...
  4. Benzoic acid
    CAS: 65-85-0 EC Number: 200-618-2 Formula: C7H6O2 Molecular Weight: 122.12
    AR ? Analytical Reagent grade — high-purity chemicals meeting strict assay limits for lab analysis. Use when accuracy matters and trace impurities could skew results. ≥99.5%
    In Stock Item #: B116255
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    IUPAC Name
    benzoic acid
    SMILES
    C1=CC=C(C=C1)C(=O)O
    InChIKey
    WPYMKLBDIGXBTP-UHFFFAOYSA-N
    InChI
    1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
    Synonyms
    Eyelids Wipes | Benzoic acid (USP:JAN) | Benzoic acid [USP:JAN] | NSC7918 | Benzenecarboxylate | Benzoic Acid 2000 mi...
  5. Ibotenic acid, Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
    CAS: 2552-55-8 EC Number: 622-405-7 Formula: C5H6N2O4 Molecular Weight: 158.11
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: A137136
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    IUPAC Name
    2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
    SMILES
    C1=C(ONC1=O)C(C(=O)O)N
    InChIKey
    IRJCBFDCFXCWGO-UHFFFAOYSA-N
    InChI
    1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
    Synonyms
    CHEBI:5854 | HMS3266E19 | Ibotenic acid, ~95%, solid | SMR001230640 | ( inverted question mark)-Ibotenic acid | HMS33...
  6. VU 0285683, Allosteric modulator of mGlu 5 receptor
    CAS: 327056-22-4 PubChem CID: 9816778 Formula: C14H7FN4O Molecular Weight: 266.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: V287791
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    IUPAC Name
    3-fluoro-5-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)benzonitrile
    SMILES
    C1=CC=NC(=C1)C2=NOC(=N2)C3=CC(=CC(=C3)C#N)F
    InChIKey
    GELAFISMURFRCA-UHFFFAOYSA-N
    InChI
    1S/C14H7FN4O/c15-11-6-9(8-16)5-10(7-11)14-18-13(19-20-14)12-3-1-2-4-17-12/h1-7H
    Synonyms
    3-Fluoro-5-[3-(2-pyridinyl)-1,2,4-oxadiazol-5-yl]-benzonitrile | 3-fluoro-5-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)be...
  7. Benzoic acid
    CAS: 65-85-0 EC Number: 200-618-2 Formula: C7H6O2 Molecular Weight: 122.12
    ACS ? ACS grade — meets American Chemical Society specifications, the analytical benchmark in the US. Use for analytical and QC work needing ACS-defined purity. ≥99.5%
    In Stock Item #: B116259
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    Technical Identifiers
    IUPAC Name
    benzoic acid
    SMILES
    C1=CC=C(C=C1)C(=O)O
    InChIKey
    WPYMKLBDIGXBTP-UHFFFAOYSA-N
    InChI
    1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
    Synonyms
    Eyelids Wipes | Benzoic acid (USP:JAN) | Benzoic acid [USP:JAN] | NSC7918 | Benzenecarboxylate | Benzoic Acid 2000 mi...
  8. MPEP, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 96206-92-7 Formula: C14H11N Molecular Weight: 193.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M127959
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    IUPAC Name
    2-methyl-6-(2-phenylethynyl)pyridine
    SMILES
    CC1=NC(=CC=C1)C#CC2=CC=CC=C2
    InChIKey
    NEWKHUASLBMWRE-UHFFFAOYSA-N
    InChI
    1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
    Synonyms
    NCGC00025044-01 | NCGC00025044-02 | Pyridine, 6-methyl-2-(phenylethynyl)- | 2-Picoline, 6-phenylethynyl- | NCGC000156...
  9. ML 289, Allosteric modulator of mGlu 3 receptor
    CAS: 1382481-79-9 EC Number: 802-823-8 Formula: C22H23NO3 Molecular Weight: 349.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: M288508
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    IUPAC Name
    [(3R)-3-(hydroxymethyl)piperidin-1-yl]-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]methanone
    SMILES
    COC1=CC=C(C=C1)C#CC2=CC=C(C=C2)C(=O)N3CCCC(C3)CO
    InChIKey
    VSLWUPHHCFQTDB-LJQANCHMSA-N
    InChI
    1S/C22H23NO3/c1-26-21-12-8-18(9-13-21)5-4-17-6-10-20(11-7-17)22(25)23-14-2-3-19(15-23)16-24/h6-13,19,24H,2-3,14-16H2,1H3/t19-/m1/s1
    Synonyms
    VU0463597 | EX-A7252 | [(3R)-1-({4-[2-(4-methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol | [(3R)-3-(Hyd...
  10. UPF-523, Antagonist of mGlu 1 receptor
    CAS: 168560-79-0 Formula: C11H11NO4 Molecular Weight: 221.21
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A286905
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    IUPAC Name
    1-amino-2,3-dihydroindene-1,5-dicarboxylic acid
    SMILES
    C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N
    InChIKey
    LSTPKMWNRWCNLS-UHFFFAOYSA-N
    InChI
    1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
    Synonyms
    L000102 | NCGC00024861-04 | AIDA | FT-0643608 | Tox21_500119 | BDBM50030630 | DTXSID60870100 | AIDC | NCGC00024861-03...
  11. A 841720, Allosteric modulator of mGlu 1 receptor
    CAS: 869802-58-4 Formula: C17H21N5OS Molecular Weight: 343.45
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: A345272
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    IUPAC Name
    5-(azepan-1-yl)-13-(dimethylamino)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
    SMILES
    CN(C)C1=C2C3=C(C(=O)N(C=N3)N4CCCCCC4)SC2=NC=C1
    InChIKey
    GYWGXEGOXODOQU-UHFFFAOYSA-N
    InChI
    1S/C17H21N5OS/c1-20(2)12-7-8-18-16-13(12)14-15(24-16)17(23)22(11-19-14)21-9-5-3-4-6-10-21/h7-8,11H,3-6,9-10H2,1-2H3
    Synonyms
    BDBM50177080 | 9-dimethylamino-3-(N-hexamethyleneiminyl)-3H-5-thia-1,3,6-triazafluoren-4-one | 9-(DIMETHYLAMINO)-3-(H...
  12. ABP 688
    CAS: 924298-51-1 Formula: C15H16N2O Molecular Weight: 240.3
    ≥98% mixture of isomers
    In Stock Item #: A287877
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    IUPAC Name
    (E)-N-methoxy-3-[2-(6-methylpyridin-2-yl)ethynyl]cyclohex-2-en-1-imine
    SMILES
    CC1=NC(=CC=C1)C#CC2=CC(=NOC)CCC2
    InChIKey
    CNNZLFXCUQLKOB-BMRADRMJSA-N
    InChI
    1S/C15H16N2O/c1-12-5-3-7-14(16-12)10-9-13-6-4-8-15(11-13)17-18-2/h3,5,7,11H,4,6,8H2,1-2H3/b17-15+
    Synonyms
    3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-oneO-methyloxime
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