Metabotropic glutamate receptor 7 (GRM7)

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  1. VU 0422288, Allosteric modulator of mGlu 8 receptor
    CAS: 1630936-95-6 PubChem CID: 73058507 Formula: C17H11Cl2N3O2 Molecular Weight: 360.19
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: V287914
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    IUPAC Name
    N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl
    InChIKey
    MZRLPXFGQKQHST-UHFFFAOYSA-N
    InChI
    1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23)
    Synonyms
    ML 396 | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide | ML396 | N-(3-Chloro-4-((5-chloropyr...
  2. VU 6005649
    CAS: 2137047-43-7 PubChem CID: 131954513 Formula: C16H12F5N3O Molecular Weight: 357.28
    In Stock Item #: V287717
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    IUPAC Name
    3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    SMILES
    CC1=NC2=C(C(=NN2C(=C1)C(F)(F)F)C)C3=C(C(=C(C=C3)OC)F)F
    InChIKey
    NYBZCKAQIIPSDS-UHFFFAOYSA-N
    InChI
    1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3
    Synonyms
    3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
  3. L-O-Phosphoserine(L-SOP), Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 407-41-0 EC Number: 206-986-0 Formula: C3H8NO6P Molecular Weight: 185.07
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(T)
    In Stock Item #: S161191
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    IUPAC Name
    (2S)-2-amino-3-phosphonooxypropanoic acid
    SMILES
    C(C(C(=O)O)N)OP(=O)(O)O
    InChIKey
    BZQFBWGGLXLEPQ-REOHCLBHSA-N
    InChI
    1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
    Synonyms
    L-SOP | CAS-407-41-0 | H-Ser(PO3H2)-OH | Phosphatidalserine | A873241 | CCG-204968 | NCGC00261571-01 | s5137 | (2S)-2...
  4. LY341495, Antagonist of mGlu 1 receptor;Antagonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 3 receptor;Antagonist of mGlu 4 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu
    CAS: 201943-63-7 Formula: C20H19NO5 Molecular Weight: 353.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: L125832
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    IUPAC Name
    (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
    InChIKey
    VLZBRVJVCCNPRJ-KPHUOKFYSA-N
    InChI
    1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/mshow more
    Synonyms
    (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid | LY341495 | LY-341495 | 1-chlo...
  5. L-AP4, Agonist of mGlu 4 receptor;Agonist of mGlu 8 receptor
    CAS: 23052-81-5 EC Number: 636-602-0 Formula: C4H10NO5P Molecular Weight: 183.1
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L274683
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    IUPAC Name
    (2S)-2-amino-4-phosphonobutanoic acid
    SMILES
    C(CP(=O)(O)O)C(C(=O)O)N
    InChIKey
    DDOQBQRIEWHWBT-VKHMYHEASA-N
    InChI
    1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
    Synonyms
    L-APB | 1-(2,5 DIMETHOXYPHENYL)-2-AMINOETHANOL | 3-METHOXY-PIPERIDINEHYDROCHLORIDE | GTPL1410 | BDBM50007548 | CHEBI:...
  6. (S)-3,4-DCPG, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 8 receptor
    CAS: 201730-11-2 EC Number: 633-834-4 Formula: C10H9NO6 Molecular Weight: 239.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: D274980
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    IUPAC Name
    4-[(S)-amino(carboxy)methyl]phthalic acid
    SMILES
    C1=CC(=C(C=C1C(C(=O)O)N)C(=O)O)C(=O)O
    InChIKey
    IJVMOGKBEVRBPP-ZETCQYMHSA-N
    InChI
    1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1
    Synonyms
    (s)-3,4dicarboxyphenylglycine | FT-0707334 | UBP 1109 | AC-30407 | J-013084 | (S)-3,4-DCPG | HMS3412E16 | HMS3676E16 ...
  7. (RS)-PPG, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 120667-15-4 PubChem CID: 4545574 Formula: C₈H₁₀NO₅P Molecular Weight: 231.14
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: R286551
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    IUPAC Name
    2-amino-2-(4-phosphonophenyl)acetic acid
    SMILES
    C1=CC(=CC=C1C(C(=O)O)N)P(=O)(O)O
    InChIKey
    JRQRKFDFHAPMGQ-UHFFFAOYSA-N
    InChI
    1S/C8H10NO5P/c9-7(8(10)11)5-1-3-6(4-2-5)15(12,13)14/h1-4,7H,9H2,(H,10,11)(H2,12,13,14)
    Synonyms
    (RS)-4-Phosphonophenylglycine
  8. ADX-88178, Allosteric modulator of mGlu 4 receptor
    CAS: 1235318-89-4 Formula: C12H12N6S Molecular Weight: 272.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A412269
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    IUPAC Name
    5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine
    SMILES
    CC1=NC(=NC=C1)NC2=NC(=C(S2)C)C3=CNN=C3
    InChIKey
    MIQNXKWDQRNHAU-UHFFFAOYSA-N
    InChI
    1S/C12H12N6S/c1-7-3-4-13-11(16-7)18-12-17-10(8(2)19-12)9-5-14-15-6-9/h3-6H,1-2H3,(H,14,15)(H,13,16,17,18)
  9. L-O-Phosphoserine, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 407-41-0 EC Number: 206-986-0 Formula: C3H8NO6P Molecular Weight: 185.07
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in Water
    In Stock Item #: L423858
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    Technical Identifiers
    IUPAC Name
    (2S)-2-amino-3-phosphonooxypropanoic acid
    SMILES
    C(C(C(=O)O)N)OP(=O)(O)O
    InChIKey
    BZQFBWGGLXLEPQ-REOHCLBHSA-N
    InChI
    1S/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/t2-/m0/s1
    Synonyms
    L-SOP | CAS-407-41-0 | H-Ser(PO3H2)-OH | Phosphatidalserine | A873241 | CCG-204968 | NCGC00261571-01 | P0773 | s5137 ...
  10. (S)-3,4-DCPG(UBP1109)
    CAS: 201730-11-2 EC Number: 633-834-4 Formula: C10H9NO6 Molecular Weight: 239.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: D276280
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    IUPAC Name
    4-[(S)-amino(carboxy)methyl]phthalic acid
    SMILES
    C1=CC(=C(C=C1C(C(=O)O)N)C(=O)O)C(=O)O
    InChIKey
    IJVMOGKBEVRBPP-ZETCQYMHSA-N
    InChI
    1S/C10H9NO6/c11-7(10(16)17)4-1-2-5(8(12)13)6(3-4)9(14)15/h1-3,7H,11H2,(H,12,13)(H,14,15)(H,16,17)/t7-/m0/s1
    Synonyms
    (s)-3,4dicarboxyphenylglycine | FT-0707334 | UBP 1109 | AC-30407 | J-013084 | (S)-3,4-DCPG | HMS3412E16 | HMS3676E16 ...
  11. (R,S)-4-PPG, Agonist of mGlu 4 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: R611150
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    IUPAC Name
    2-amino-2-(4-phosphonophenyl)acetic acid
    SMILES
    OC(=O)C(c1ccc(cc1)P(=O)(O)O)N
    InChIKey
    JRQRKFDFHAPMGQ-UHFFFAOYSA-N
    InChI
    1S/C8H10NO5P/c9-7(8(10)11)5-1-3-6(4-2-5)15(12,13)14/h1-4,7H,9H2,(H,10,11)(H2,12,13,14)
    Synonyms
    (R,S)-4-phosphonophenylglycine;(RS)PPG
  12. A-794282, Allosteric modulator of mGlu 1 receptor
    CAS: 869802-44-8 PubChem CID: 11530404 Formula: C19H18N4OS Molecular Weight: 350.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A607307
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    IUPAC Name
    13-(dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one
    SMILES
    CCc1ccc(cc1)n1cnc2c(c1=O)sc1c2c(ccn1)N(C)C
    InChIKey
    VCUKKMIXURRDKL-UHFFFAOYSA-N
    InChI
    1S/C19H18N4OS/c1-4-12-5-7-13(8-6-12)23-11-21-16-15-14(22(2)3)9-10-20-18(15)25-17(16)19(23)24/h5-11H,4H2,1-3H3
    Synonyms
    13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one ...
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