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Metabotropic glutamate receptor 8 (GRM8)

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  1. L-CCG-l, Agonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 4 receptor;Agonist of mGlu 5 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
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    L-CCG-l, Agonist of mGlu 1 receptor;Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 4 receptor;Agonist of mGlu 5 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 7 receptor;Agonist of mGlu 8 receptor
    CAS: 117857-93-9 Formula: C6H9NO4 Molecular Weight: 159.14
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC)
    Out of Stock Item #: L287585
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    IUPAC Name
    (1S,2S)-2-[(S)-amino(carboxy)methyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(=O)O)C(C(=O)O)N
    InChIKey
    GZOVEPYOCJWRFC-HZLVTQRSSA-N
    InChI
    1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3-,4-/m0/s1
    Synonyms
    AM85789 | L-CCG I | NCGC00024541-02 | SCHEMBL664330 | 2-(Amino-carboxy-methyl)-cyclopropanecarboxylic acid(2S,3S,4S-C...
  2. VU 0422288 - Moligand™, ≥98%(HPLC) CAS No(1630936-95-6) by Aladdin Scientific
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    VU 0422288, Allosteric modulator of mGlu 8 receptor
    CAS: 1630936-95-6 PubChem CID: 73058507 Formula: C17H11Cl2N3O2 Molecular Weight: 360.19
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: V287914
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    IUPAC Name
    N-[3-chloro-4-(5-chloropyridin-2-yl)oxyphenyl]pyridine-2-carboxamide
    SMILES
    C1=CC=NC(=C1)C(=O)NC2=CC(=C(C=C2)OC3=NC=C(C=C3)Cl)Cl
    InChIKey
    MZRLPXFGQKQHST-UHFFFAOYSA-N
    InChI
    1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23)
    Synonyms
    ML 396 | N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide | ML396 | N-(3-Chloro-4-((5-chloropyr...
  3. VU 6005649
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    VU 6005649
    CAS: 2137047-43-7 PubChem CID: 131954513 Formula: C16H12F5N3O Molecular Weight: 357.28
    ≥98%(HPLC)
    In Stock Item #: V287717
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    IUPAC Name
    3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    SMILES
    CC1=NC2=C(C(=NN2C(=C1)C(F)(F)F)C)C3=C(C(=C(C=C3)OC)F)F
    InChIKey
    NYBZCKAQIIPSDS-UHFFFAOYSA-N
    InChI
    1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3
    Synonyms
    3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
  4. LY341495, Antagonist of mGlu 1 receptor;Antagonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 3 receptor;Antagonist of mGlu 4 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu
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    LY341495, Antagonist of mGlu 1 receptor;Antagonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Antagonist of mGlu 3 receptor;Antagonist of mGlu 4 receptor;Antagonist of mGlu 5 receptor;Antagonist of mGlu 6 receptor;Antagonist of mGlu 7 receptor;Antagonist of mGlu
    CAS: 201943-63-7 Formula: C20H19NO5 Molecular Weight: 353.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: L125832
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    IUPAC Name
    (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
    SMILES
    C1C(C1C(CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O
    InChIKey
    VLZBRVJVCCNPRJ-KPHUOKFYSA-N
    InChI
    1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/mshow more
    Synonyms
    (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid | LY341495 | LY-341495 | 1-chlo...
  5. FITM, Allosteric modulator of mGlu 1 receptor
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    FITM, Allosteric modulator of mGlu 1 receptor
    CAS: 932737-65-0 Formula: C18H18FN5OS Molecular Weight: 371.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: F288564
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    IUPAC Name
    4-fluoro-N-methyl-N-[4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]benzamide
    SMILES
    CC(C)NC1=NC=NC(=C1)C2=CSC(=N2)N(C)C(=O)C3=CC=C(C=C3)F
    InChIKey
    WIVGIKIKQHUFOD-UHFFFAOYSA-N
    InChI
    1S/C18H18FN5OS/c1-11(2)22-16-8-14(20-10-21-16)15-9-26-18(23-15)24(3)17(25)12-4-6-13(19)7-5-12/h4-11H,1-3H3,(H,20,21,22)
    Synonyms
    4-Fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide
  6. L-AP4 - Moligand™, ≥99% CAS No(23052-81-5) L274683 by Aladdin Scientific
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    L-AP4, Agonist of mGlu 4 receptor;Agonist of mGlu 8 receptor
    CAS: 23052-81-5 EC Number: 636-602-0 Formula: C4H10NO5P Molecular Weight: 183.1
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L274683
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    IUPAC Name
    (2S)-2-amino-4-phosphonobutanoic acid
    SMILES
    C(CP(=O)(O)O)C(C(=O)O)N
    InChIKey
    DDOQBQRIEWHWBT-VKHMYHEASA-N
    InChI
    1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
    Synonyms
    L-APB | 1-(2,5 DIMETHOXYPHENYL)-2-AMINOETHANOL | 3-METHOXY-PIPERIDINEHYDROCHLORIDE | GTPL1410 | BDBM50007548 | CHEBI:...
  7. L-Glutamic acid polymer, Nutritional support
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    L-Glutamic acid polymer, Nutritional support
    CAS: 25513-46-6 EC Number: 801-964-2 Formula: (C5H9NO4)x
    MW:＞700000
    In Stock Item #: G301751
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    Technical Identifiers
    IUPAC Name
    (2S)-2-aminopentanedioic acid
    SMILES
    C(CC(=O)O)C(C(=O)O)N
    InChIKey
    WHUUTDBJXJRKMK-VKHMYHEASA-N
    InChI
    1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
    Synonyms
    DTXCID30659 | glt | 1ii5 | Glutamate, L- | Glutamic acid, (S)- | Glutaton | glutamate | L-Glutaminic acid | Gamma-L-G...
  8. L(+)-Glutamic acid
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    L(+)-Glutamic acid
    CAS: 56-86-0 EC Number: 200-293-7 Formula: C5H9NO4 Molecular Weight: 147.13
    Solid Ultra pure ? Ultra-pure grade with very low impurity content across the board. Use for trace analysis, electronics, or processes intolerant of contamination. ≥99.5%(NT)
    In Stock Item #: G103979
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    Technical Identifiers
    IUPAC Name
    (2S)-2-aminopentanedioic acid
    SMILES
    C(CC(=O)O)C(C(=O)O)N
    InChIKey
    WHUUTDBJXJRKMK-VKHMYHEASA-N
    InChI
    1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
    Synonyms
    H-Glu-OH | (S)-2-Aminopentanedioic acid | L-2-Aminoglutaric acid
  9. L(+)-Glutamic acid - Animal Free, USP, JP, Ph.Eur., for cell culture, ≥98.5% CAS No(56-86-0) by Aladdin Scientific
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    L(+)-Glutamic acid
    CAS: 56-86-0 EC Number: 200-293-7 Formula: C5H9NO4 Molecular Weight: 147.13
    Solid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. USP ? United States Pharmacopeia grade — meets USP monograph specs for pharmaceutical use. Use for drug manufacturing, QC, and applications requiring US compendial compliance. JP ? Japanese Pharmacopoeia grade — conforms to JP monograph standards. Use for pharmaceutical products subject to Japanese regulatory requirements. Ph.Eur. ? European Pharmacopoeia grade — conforms to Ph.Eur. monographs across EU member states. Use for pharmaceutical work needing European compendial compliance. for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. ≥98.5%
    In Stock Item #: G107510
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    Technical Identifiers
    IUPAC Name
    (2S)-2-aminopentanedioic acid
    SMILES
    C(CC(=O)O)C(C(=O)O)N
    InChIKey
    WHUUTDBJXJRKMK-VKHMYHEASA-N
    InChI
    1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
    Synonyms
    DTXCID30659 | glt | 1ii5 | Glutamate, L- | Glutamic acid, (S)- | Glutaton | glutamate | L-Glutaminic acid | Gamma-L-G...
  10. L(+)-Glutamic acid - ≥99% CAS No(56-86-0) by Aladdin Scientific
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    L(+)-Glutamic acid
    CAS: 56-86-0 EC Number: 200-293-7 Formula: C5H9NO4 Molecular Weight: 147.13
    Solid ≥99%
    In Stock Item #: G103978
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    Technical Identifiers
    IUPAC Name
    (2S)-2-aminopentanedioic acid
    SMILES
    C(CC(=O)O)C(C(=O)O)N
    InChIKey
    WHUUTDBJXJRKMK-VKHMYHEASA-N
    InChI
    1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
    Synonyms
    DTXCID30659 | glt | 1ii5 | Glutamate, L- | Glutamic acid, (S)- | Glutaton | glutamate | L-Glutaminic acid | Gamma-L-G...
  11. LY404039, Metabotropic glutamate receptor 3 agonist
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    LY404039, Metabotropic glutamate receptor 3 agonist
    CAS: 635318-11-5 EC Number: 802-107-5 Formula: C7H9NO6S Molecular Weight: 235.21
    ≥98%
    In Stock Item #: L127760
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    Technical Identifiers
    IUPAC Name
    (1R,4S,5S,6S)-4-amino-2,2-dioxo-2λ6-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
    SMILES
    C1C(C2C(C2S1(=O)=O)C(=O)O)(C(=O)O)N
    InChIKey
    AVDUGNCTZRCAHH-MDASVERJSA-N
    InChI
    1S/C7H9NO6S/c8-7(6(11)12)1-15(13,14)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1
    Synonyms
    (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide | ;(1R,4S,5S,6S)-4-Amino-2-thiabic...
  12. LY 354740, Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 8 receptor
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    LY 354740, Agonist of mGlu 2 receptor;Agonist of mGlu 3 receptor;Agonist of mGlu 6 receptor;Agonist of mGlu 8 receptor
    CAS: 176199-48-7 Formula: C8H11NO4 Molecular Weight: 185.18
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: L275282
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    Technical Identifiers
    IUPAC Name
    (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
    SMILES
    C1CC(C2C1C2C(=O)O)(C(=O)O)N
    InChIKey
    VTAARTQTOOYTES-RGDLXGNYSA-N
    InChI
    1S/C8H11NO4/c9-8(7(12)13)2-1-3-4(5(3)8)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8-/m0/s1
    Synonyms
    DTXSID40170094 | Eglumetad anhydrous | NCGC00485401-01 | Q5348096 | LY366563 | (+)-(1S,2S,5R,6S)-2-aminobicyclo(3.1.0...
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