Probable G-protein coupled receptor 52 (GPR52)

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  1. FTBMT
    CAS: 1358575-02-6 Formula: C19H16F4N4O Molecular Weight: 392.35
    Out of Stock Item #: F288397
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    Technical Identifiers
    IUPAC Name
    4-[3-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1,2,4-triazol-1-yl]-2-methylbenzamide
    SMILES
    CC1=C(C=CC(=C1)N2C(=NC(=N2)CC3=CC(=CC(=C3)F)C(F)(F)F)C)C(=O)N
    InChIKey
    TYXSIXOYTBHZFA-UHFFFAOYSA-N
    InChI
    1S/C19H16F4N4O/c1-10-5-15(3-4-16(10)18(24)28)27-11(2)25-17(26-27)8-12-6-13(19(21,22)23)9-14(20)7-12/h3-7,9H,8H2,1-2H3,(H2,24,28)
    Synonyms
    4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide
  2. 1,7-Diphenyl-4-hepten-3-one
    CAS: 79559-59-4 Formula: C19H20O Molecular Weight: 264.36
    Out of Stock Item #: D463963
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    IUPAC Name
    (E)-1,7-diphenylhept-4-en-3-one
    SMILES
    C1=CC=C(C=C1)CCC=CC(=O)CCC2=CC=CC=C2
    InChIKey
    UDNMYDZHPMNIEQ-RIYZIHGNSA-N
    InChI
    1S/C19H20O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-6,8-12,14H,7,13,15-16H2/b14-8+
    Synonyms
    ACon1_001294 | DAH-3-Keto-4-en | SCHEMBL6373065 | 1,7-diphenyl-4-hepten-3-one | BRD-K64408267-001-01-9 | FS-7901 | (4...
  3. derivative 17 [Nakahata et al., 2018], Agonist of GPR52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: D609812
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    IUPAC Name
    N-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamide
    SMILES
    OCCNC(=O)c1c(C)nn(c1CO)c1cccc2c1sc(c2)Cc1cccc(c1)C(F)(F)F
    InChIKey
    VJMRKWPMFQGIPI-UHFFFAOYSA-N
    InChI
    1S/C24H22F3N3O3S/c1-14-21(23(33)28-8-9-31)20(13-32)30(29-14)19-7-3-5-16-12-18(34-22(16)19)11-15-4-2-6-17(10-15)24(25,26)27/h2-7,10,12,31-32H,8-9,11,13show more
    Synonyms
    example 65 [WO2011078360]
  4. N-(2-hydroxyethyl)-3-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzofuran-4-yl]benzamide, Agonist of GPR52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N609406
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    IUPAC Name
    N-(2-hydroxyethyl)-3-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzofuran-4-yl]benzamide
    SMILES
    OCCNC(=O)c1cccc(c1)c1cccc2c1cc(o2)Cc1cccc(c1)C(F)(F)F
    InChIKey
    LBKIJSKRXVUWER-UHFFFAOYSA-N
    InChI
    1S/C25H20F3NO3/c26-25(27,28)19-7-1-4-16(12-19)13-20-15-22-21(8-3-9-23(22)32-20)17-5-2-6-18(14-17)24(31)29-10-11-30/h1-9,12,14-15,30H,10-11,13H2,(H,29,show more
    Synonyms
    compound 7a
  5. PW0787
    CAS: 2624131-45-7 PubChem CID: 155977949 Formula: C23H20F4N4O2 Molecular Weight: 460.4
    Out of Stock Item #: P646822
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    IUPAC Name
    1-[6-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]pyrimidin-4-yl]-N-(2-hydroxyethyl)-2,3-dihydroindole-4-carboxamide
    SMILES
    C1CN(C2=CC=CC(=C21)C(=O)NCCO)C3=NC=NC(=C3)CC4=CC(=CC(=C4)F)C(F)(F)F
    InChIKey
    OLNVWBLTVAPNME-UHFFFAOYSA-N
    InChI
    1S/C23H20F4N4O2/c24-16-9-14(8-15(11-16)23(25,26)27)10-17-12-21(30-13-29-17)31-6-4-18-19(2-1-3-20(18)31)22(33)28-5-7-32/h1-3,8-9,11-13,32H,4-7,10H2,(H,show more
  6. GPR52 antagonist-1
    CAS: 1239987-91-7 PubChem CID: 156588927 Formula: C15H14OS Molecular Weight: 242.34
    Out of Stock Item #: G648112
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    IUPAC Name
    (E)-5-phenyl-1-thiophen-2-ylpent-2-en-1-one
    SMILES
    C1=CC=C(C=C1)CCC=CC(=O)C2=CC=CS2
    InChIKey
    XUIAIACHIPOOHR-BJMVGYQFSA-N
    InChI
    1S/C15H14OS/c16-14(15-11-6-12-17-15)10-5-4-9-13-7-2-1-3-8-13/h1-3,5-8,10-12H,4,9H2/b10-5+
  7. PW0787
    CAS: 2624131-45-7 PubChem CID: 155977949 Formula: C23H20F4N4O2 Molecular Weight: 460.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: P1496710
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  8. TP-024
    CAS: 1358575-02-6 Formula: C19H16F4N4O Molecular Weight: 392.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: T1493456
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