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Potassium voltage-gated channel subfamily KQT member 2 (KCNQ2)

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  1. ML 277, Activator of K v7.1
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    ML 277, Activator of K v7.1
    CAS: 1401242-74-7 Formula: C23H25N3O4S2 Molecular Weight: 471.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: M288427
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    Technical Identifiers
    IUPAC Name
    (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C(=O)NC3=NC(=CS3)C4=CC=C(C=C4)OC
    InChIKey
    OXQNLLVUVDAEHC-OAQYLSRUSA-N
    InChI
    1S/C23H25N3O4S2/c1-16-6-12-19(13-7-16)32(28,29)26-14-4-3-5-21(26)22(27)25-23-24-20(15-31-23)17-8-10-18(30-2)11-9-17/h6-13,15,21H,3-5,14H2,1-2H3,(H,24,show more
    Synonyms
    (2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide | ML277 | CID-53347902,...
  2. XE-991, Inhibitor of K v7.1;Inhibitor of K v7.2;Inhibitor of K v7.4;Inhibitor of K v7.5
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    XE-991, Inhibitor of K v7.1;Inhibitor of K v7.2;Inhibitor of K v7.4;Inhibitor of K v7.5
    CAS: 122955-42-4 EC Number: 687-389-6 PubChem CID: 45073462 Formula: C26H20N2O Molecular Weight: 376.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: X335126
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    IUPAC Name
    10,10-bis(pyridin-4-ylmethyl)anthracen-9-one;dihydrochloride
    SMILES
    C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3C2(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
    InChIKey
    WOGWMARIFDNZON-UHFFFAOYSA-N
    InChI
    1S/C26H20N2O.2ClH/c29-25-21-5-1-3-7-23(21)26(17-19-9-13-27-14-10-19,18-20-11-15-28-16-12-20)24-8-4-2-6-22(24)25;;/h1-16H,17-18H2;2*1H
    Synonyms
    XE 991 | SR-01000597960-1 | XE 991 dihydrochloride | s2967 | XE991Dihydrochloride | 10,10-bis(pyridin-4-ylmethyl)anth...
  3. ML 365
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    ML 365
    CAS: 947914-18-3 Formula: C22H20N2O3 Molecular Weight: 360.41
    ≥98%
    In Stock Item #: M287099
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    Technical Identifiers
    IUPAC Name
    2-methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide
    SMILES
    CC1=CC(=CC=C1)C(=O)NC2=CC(=CC=C2)NC(=O)C3=CC=CC=C3OC
    InChIKey
    UTAJHKSGYJSZBR-UHFFFAOYSA-N
    InChI
    1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
    Synonyms
    ML365 | 2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide | 2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide
  4. ML213, Activator of K v7.4
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    ML213, Activator of K v7.4
    CAS: 489402-47-3 EC Number: 803-886-4 Formula: C17H23NO Molecular Weight: 257.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: M170566
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    IUPAC Name
    N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
    SMILES
    CC1=CC(=C(C(=C1)C)NC(=O)C2CC3CCC2C3)C
    InChIKey
    SIQGKPGBLYKQBB-UHFFFAOYSA-N
    InChI
    1S/C17H23NO/c1-10-6-11(2)16(12(3)7-10)18-17(19)15-9-13-4-5-14(15)8-13/h6-7,13-15H,4-5,8-9H2,1-3H3,(H,18,19)
    Synonyms
    N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-6-carboxamide | ML213 | ML-213 | MLS003370512 | SMR000514557 | EX-A255...
  5. MaxiPost, Voltage-gated potassium channel KCNQ3/KCNQ4 activator
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    MaxiPost, Voltage-gated potassium channel KCNQ3/KCNQ4 activator
    CAS: 187523-35-9 EC Number: 110-105-4 Formula: C16H10ClF4NO2 Molecular Weight: 359.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: M287135
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    IUPAC Name
    (3S)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)-1H-indol-2-one
    SMILES
    COC1=C(C=C(C=C1)Cl)C2(C3=C(C=C(C=C3)C(F)(F)F)NC2=O)F
    InChIKey
    ULYONBAOIMCNEH-HNNXBMFYSA-N
    InChI
    1S/C16H10ClF4NO2/c1-24-13-5-3-9(17)7-11(13)15(18)10-4-2-8(16(19,20)21)6-12(10)22-14(15)23/h2-7H,1H3,(H,22,23)/t15-/m0/s1
    Synonyms
    (S)-II | FLINDOKALNER [INN] | HMS555I10 | (S)-3-(5-Chloro-2-methoxy-phenyl)-3-fluoro-6-trifluoromethyl-1,3-dihydro-in...
  6. DMP 543
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    DMP 543
    CAS: 160588-45-4 Formula: C26H18F2N2O Molecular Weight: 412.44
    ≥98%
    In Stock Item #: D288728
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    Technical Identifiers
    IUPAC Name
    10,10-bis[(2-fluoropyridin-4-yl)methyl]anthracen-9-one
    SMILES
    C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3C2(CC4=CC(=NC=C4)F)CC5=CC(=NC=C5)F
    InChIKey
    MUJBUUDUXGDXLW-UHFFFAOYSA-N
    InChI
    1S/C26H18F2N2O/c27-23-13-17(9-11-29-23)15-26(16-18-10-12-30-24(28)14-18)21-7-3-1-5-19(21)25(31)20-6-2-4-8-22(20)26/h1-14H,15-16H2
    Synonyms
    FT-0643556 | AC-28096 | BRD-K89274813-001-01-5 | NSC116211 | 9(10H)-Anthracenone, 10,10-bis[(2-fluoro-4-pyridinyl)met...
  7. ML 277, Activator of K v7.1
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    ML 277, Activator of K v7.1
    CAS: 1401242-74-7 Formula: C23H25N3O4S2 Molecular Weight: 471.59
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M421499
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    Technical Identifiers
    IUPAC Name
    (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C(=O)NC3=NC(=CS3)C4=CC=C(C=C4)OC
    InChIKey
    OXQNLLVUVDAEHC-OAQYLSRUSA-N
    InChI
    1S/C23H25N3O4S2/c1-16-6-12-19(13-7-16)32(28,29)26-14-4-3-5-21(26)22(27)25-23-24-20(15-31-23)17-8-10-18(30-2)11-9-17/h6-13,15,21H,3-5,14H2,1-2H3,(H,24,show more
    Synonyms
    (2R)-N-[4-(4-Methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide；ML277；CID-53347902, (2R...
  8. ML 365
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    ML 365
    CAS: 947914-18-3 Formula: C22H20N2O3 Molecular Weight: 360.41
    10mM in DMSO
    In Stock Item #: M427054
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    Technical Identifiers
    IUPAC Name
    2-methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide
    SMILES
    CC1=CC(=CC=C1)C(=O)NC2=CC(=CC=C2)NC(=O)C3=CC=CC=C3OC
    InChIKey
    UTAJHKSGYJSZBR-UHFFFAOYSA-N
    InChI
    1S/C22H20N2O3/c1-15-7-5-8-16(13-15)21(25)23-17-9-6-10-18(14-17)24-22(26)19-11-3-4-12-20(19)27-2/h3-14H,1-2H3,(H,23,25)(H,24,26)
    Synonyms
    ML365;ML365;2-Methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]benzamide;2-methoxy-N-(3-(3-methylbenzamido)phenyl)benzamide
  9. ML213, Activator of K v7.4
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    ML213, Activator of K v7.4
    CAS: 489402-47-3 EC Number: 803-886-4 Formula: C17H23NO Molecular Weight: 257.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M424236
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    Technical Identifiers
    IUPAC Name
    N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
    SMILES
    CC1=CC(=C(C(=C1)C)NC(=O)C2CC3CCC2C3)C
    InChIKey
    SIQGKPGBLYKQBB-UHFFFAOYSA-N
    InChI
    1S/C17H23NO/c1-10-6-11(2)16(12(3)7-10)18-17(19)15-9-13-4-5-14(15)8-13/h6-7,13-15H,4-5,8-9H2,1-3H3,(H,18,19)
    Synonyms
    N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-6-carboxamide | ML213 | ML-213 | MLS003370512 | SMR000514557 | EX-A255...
  10. no_selection
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    ICA-27243, Activator of K v7.2
    CAS: 325457-89-4 PubChem CID: 9903497 Formula: C12H7ClF2N2O Molecular Weight: 268.65
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: I610913
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    Technical Identifiers
    IUPAC Name
    N-(6-chloropyridin-3-yl)-3,4-difluorobenzamide
    SMILES
    C1=CC(=C(C=C1C(=O)NC2=CN=C(C=C2)Cl)F)F
    InChIKey
    GDGUOCFTHNGPBK-UHFFFAOYSA-N
    InChI
    1S/C12H7ClF2N2O/c13-11-4-2-8(6-16-11)17-12(18)7-1-3-9(14)10(15)5-7/h1-6H,(H,17,18)
    Synonyms
    I-130 | UNII-VU7278D853 | W10725 | ICA 27243 | VU0409857-1 | ZTZ233 | A1-06007 | BDBM50420049 | VU7278D853 | Q2707802...
  11. flupirtine, Activator of K v7.2
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    flupirtine, Activator of K v7.2
    CAS: 56995-20-1 EC Number: 260-503-8 PubChem CID: 53276 Formula: C15H17FN4O2 Molecular Weight: 304.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F610357
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    Technical Identifiers
    IUPAC Name
    ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate
    SMILES
    CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N
    InChIKey
    JUUFBMODXQKSTD-UHFFFAOYSA-N
    InChI
    1S/C15H17FN4O2/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)
    Synonyms
    Flupirtine (INN) | ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate | Flupirtine | FLUPIRTINE [...
  12. no_selection
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    ztz240, Activator of K v7.2
    CAS: 325457-98-5 PubChem CID: 3780776 Formula: C12H8ClFN2O Molecular Weight: 250.66
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: Z614988
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    Technical Identifiers
    IUPAC Name
    N-(6-chloropyridin-3-yl)-4-fluorobenzamide
    SMILES
    C1=CC(=CC=C1C(=O)NC2=CN=C(C=C2)Cl)F
    InChIKey
    URPKVELJRWKNQS-UHFFFAOYSA-N
    InChI
    1S/C12H8ClFN2O/c13-11-6-5-10(7-15-11)16-12(17)8-1-3-9(14)4-2-8/h1-7H,(H,16,17)
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