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Lim domain kinase 1 (LIMK1)

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  1. SR 7826, Inhibitor of LIM domain kinase 1
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    SR 7826, Inhibitor of LIM domain kinase 1
    CAS: 1219728-20-7 PubChem CID: 45381385 Formula: C22H21N5O2 Molecular Weight: 387.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S286759
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    IUPAC Name
    1-(2-hydroxyethyl)-3-[4-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]-1-phenylurea
    SMILES
    CC1=CNC2=NC=NC(=C12)C3=CC=C(C=C3)NC(=O)N(CCO)C4=CC=CC=C4
    InChIKey
    WQAGVQVBDHOHRD-UHFFFAOYSA-N
    InChI
    1S/C22H21N5O2/c1-15-13-23-21-19(15)20(24-14-25-21)16-7-9-17(10-8-16)26-22(29)27(11-12-28)18-5-3-2-4-6-18/h2-10,13-14,28H,11-12H2,1H3,(H,26,29)(H,23,24show more
    Synonyms
    N-(2-Hydroxyethyl)-N'-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea | SR7826 | SR-7826
  2. LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
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    LIMKi 3, Inhibitor of LIM domain kinase 1;Inhibitor of LIM domain kinase 2
    CAS: 1338247-35-0 Formula: C17H14Cl2F2N4OS Molecular Weight: 431.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: L288407
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    IUPAC Name
    N-[5-[2-(2,6-dichlorophenyl)-5-(difluoromethyl)pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methylpropanamide
    SMILES
    CC(C)C(=O)NC1=NC=C(S1)C2=CC(=NN2C3=C(C=CC=C3Cl)Cl)C(F)F
    InChIKey
    IVUGBSGLHRJSSP-UHFFFAOYSA-N
    InChI
    1S/C17H14Cl2F2N4OS/c1-8(2)16(26)23-17-22-7-13(27-17)12-6-11(15(20)21)24-25(12)14-9(18)4-3-5-10(14)19/h3-8,15H,1-2H3,(H,22,23,26)
    Synonyms
    J-523083 | LIMKI-3 (BMS-5) | GTPL9839 | HMS3743I19 | BMS 5 | LIM Kinase Inhibitor I | N-[5-[2-(2,6-dichlorophenyl)-5-...
  3. Ethyl 3-aminobenzo[b]thiophene-2-carboxylate
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    Ethyl 3-aminobenzo[b]thiophene-2-carboxylate
    CAS: 34761-09-6 EC Number: 127-292-3 Formula: C11H11NO2S Molecular Weight: 221.28
    Solid ≥97%
    In Stock Item #: E192896
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    IUPAC Name
    ethyl 3-amino-1-benzothiophene-2-carboxylate
    SMILES
    CCOC(=O)C1=C(C2=CC=CC=C2S1)N
    InChIKey
    XZSFZYVMRZLUOJ-UHFFFAOYSA-N
    InChI
    1S/C11H11NO2S/c1-2-14-11(13)10-9(12)7-5-3-4-6-8(7)15-10/h3-6H,2,12H2,1H3
    Synonyms
    BS-4299 | ethyl 3-amino-1-benzothiophene-2-carboxylate | EN300-53562 | Maybridge1_003360 | A874869 | F1606-0080 | eth...
  4. T 5601640
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    T 5601640
    CAS: 924473-59-6 EC Number: 110-093-0 PubChem CID: 9438169 Formula: C19H14F3N3O3 Molecular Weight: 389.33
    ≥99%(HPLC)
    In Stock Item #: T287261
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    IUPAC Name
    3-methyl-N-[3-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl]-1,2-oxazole-5-carboxamide
    SMILES
    CC1=NOC(=C1)C(=O)NC2=CC=CC(=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F
    InChIKey
    XVOKFRPKSAWELK-UHFFFAOYSA-N
    InChI
    1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)
    Synonyms
    T56-LIMKi | 3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide | 3-methyl-N-(3-...
  5. AZ 960, Inhibitor of Janus kinase 2
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    AZ 960, Inhibitor of Janus kinase 2
    CAS: 905586-69-8 Formula: C18H16F2N6 Molecular Weight: 354.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A129464
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    IUPAC Name
    5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile
    SMILES
    CC1=CC(=NN1)NC2=C(C=C(C(=N2)NC(C)C3=CC=C(C=C3)F)C#N)F
    InChIKey
    SUNXHXDJOIXABJ-NSHDSACASA-N
    InChI
    1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1
    Synonyms
    (S)-5-fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile | NCGC00346581-01 ...
  6. Thieno[2,3-d]pyrimidin-4-ylamine
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    Thieno[2,3-d]pyrimidin-4-ylamine
    CAS: 14080-56-9 EC Number: 874-823-6 PubChem CID: 4269486 Formula: C6H5N3S Molecular Weight: 151.19
    Solid ≥98%
    In Stock Item #: T347658
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    Technical Identifiers
    IUPAC Name
    thieno[2,3-d]pyrimidin-4-amine
    SMILES
    C1=CSC2=NC=NC(=C21)N
    InChIKey
    DYTQGJLVGDSCLF-UHFFFAOYSA-N
    InChI
    1S/C6H5N3S/c7-5-4-1-2-10-6(4)9-3-8-5/h1-3H,(H2,7,8,9)
    Synonyms
    DYTQGJLVGDSCLF-UHFFFAOYSA-N | thieno[2,3-d]pyrimidin-4-amine | Z316122296 | AB1043 | EN300-247083 | Thieno[2,3-d]pyri...
  7. TH 257
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    TH 257
    CAS: 2244678-29-1 PubChem CID: 137796294 Formula: C24H26N2O3S Molecular Weight: 422.54
    ≥98%(HPLC)
    In Stock Item #: T287707
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    IUPAC Name
    N-benzyl-N-butyl-4-(phenylsulfamoyl)benzamide
    SMILES
    CCCCN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3
    InChIKey
    VNCIWNGCMAKKEO-UHFFFAOYSA-N
    InChI
    1S/C24H26N2O3S/c1-2-3-18-26(19-20-10-6-4-7-11-20)24(27)21-14-16-23(17-15-21)30(28,29)25-22-12-8-5-9-13-22/h4-17,25H,2-3,18-19H2,1H3
    Synonyms
    N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide
  8. FRAX 486, Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of p21 (RAC1) activated kinase 2;Inhibitor of p21 (RAC1) activated kinase 3;Inhibitor of p21 (RAC1) activated kinase 4
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    FRAX 486, Inhibitor of p21 (RAC1) activated kinase 1;Inhibitor of p21 (RAC1) activated kinase 2;Inhibitor of p21 (RAC1) activated kinase 3;Inhibitor of p21 (RAC1) activated kinase 4
    CAS: 1232030-35-1 Formula: C25H23Cl2FN6O Molecular Weight: 513.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    In Stock Item #: F286996
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    IUPAC Name
    6-(2,4-dichlorophenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one
    SMILES
    CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F
    InChIKey
    DHKFOIHIUYFSOF-UHFFFAOYSA-N
    InChI
    1S/C25H23Cl2FN6O/c1-2-34-23-15(11-19(24(34)35)18-5-3-16(26)12-20(18)27)14-30-25(32-23)31-17-4-6-22(21(28)13-17)33-9-7-29-8-10-33/h3-6,11-14,29H,2,7-10show more
    Synonyms
    FRAX486 | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one,...
  9. PHA-680632
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    PHA-680632
    CAS: 398493-79-3 Formula: C28H35N7O2 Molecular Weight: 501.64
    ≥98%
    In Stock Item #: P125501
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    Technical Identifiers
    IUPAC Name
    N-(2,6-diethylphenyl)-3-[[4-(4-methylpiperazin-1-yl)benzoyl]amino]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazole-5-carboxamide
    SMILES
    CCC1=C(C(=CC=C1)CC)NC(=O)N2CC3=C(C2)NN=C3NC(=O)C4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    OBWNXGOQPLDDPS-UHFFFAOYSA-N
    InChI
    1S/C28H35N7O2/c1-4-19-7-6-8-20(5-2)25(19)29-28(37)35-17-23-24(18-35)31-32-26(23)30-27(36)21-9-11-22(12-10-21)34-15-13-33(3)14-16-34/h6-12H,4-5,13-18H2show more
    Synonyms
    A24276 | HMS3269C15 | N-(2,6-diethylphenyl)-3-(4-(4-methylpiperazin-1-yl)benzamido)pyrrolo[3,4-c]pyrazole-5(1H,4H,6H)...
  10. 3-Phenylimidazo[1,5-a]pyridine
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    3-Phenylimidazo[1,5-a]pyridine
    CAS: 35854-46-7 PubChem CID: 606670 Formula: C13H10N2 Molecular Weight: 194.24
    ≥97%
    Out of Stock Item #: P160237
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    Technical Identifiers
    IUPAC Name
    3-phenylimidazo[1,5-a]pyridine
    SMILES
    C1=CC=C(C=C1)C2=NC=C3N2C=CC=C3
    InChIKey
    BLGGTXOVNVHSSV-UHFFFAOYSA-N
    InChI
    1S/C13H10N2/c1-2-6-11(7-3-1)13-14-10-12-8-4-5-9-15(12)13/h1-10H
    Synonyms
    AKOS000809059 | DP 01774 | Oprea1_802822 | DTXSID70345733 | HMS2807H22 | Z57214517 | SMR000457872 | MLS000851429 | EN...
  11. 3-Amino-6-chloro-4-phenylquinolin-2(1H)-one
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    3-Amino-6-chloro-4-phenylquinolin-2(1H)-one
    CAS: 5220-83-7 EC Number: 822-606-1 Formula: C15H11ClN2O Molecular Weight: 270.71
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: A331137
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    Technical Identifiers
    IUPAC Name
    3-amino-6-chloro-4-phenyl-1H-quinolin-2-one
    SMILES
    C1=CC=C(C=C1)C2=C(C(=O)NC3=C2C=C(C=C3)Cl)N
    InChIKey
    DTVBJIVUGSOZDZ-UHFFFAOYSA-N
    InChI
    1S/C15H11ClN2O/c16-10-6-7-12-11(8-10)13(14(17)15(19)18-12)9-4-2-1-3-5-9/h1-8H,17H2,(H,18,19)
    Synonyms
    Oprea1_504590 | 3-Amino-6-chloro-4-phenyl-1H-quinolin-2-one | 3-amino-6-chloro-4-phenylquinolin-2-ol | STK380592 | AK...
  12. 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
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    3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
    CAS: 67795-42-0 EC Number: 154-574-3 PubChem CID: 613528 Formula: C10H11N3OS Molecular Weight: 221.28
    ≥98%
    In Stock Item #: W418014
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    Technical Identifiers
    IUPAC Name
    3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
    SMILES
    CC1=CC(=NC2=C1C(=C(S2)C(=O)N)N)C
    InChIKey
    SDMLKCQDZJOSDN-UHFFFAOYSA-N
    InChI
    1S/C10H11N3OS/c1-4-3-5(2)13-10-6(4)7(11)8(15-10)9(12)14/h3H,11H2,1-2H3,(H2,12,14)
    Synonyms
    HMS1440A19 | 3-amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide | 3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-c...
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