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Mitogen-activated protein kinase 14 (MAPK14)

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  1. Zafirlukast, Cysteinyl leukotriene receptor 1 antagonist
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    Zafirlukast, Cysteinyl leukotriene receptor 1 antagonist
    CAS: 107753-78-6 EC Number: 663-705-8 PubChem CID: 5717 Formula: C31H33N3O6S Molecular Weight: 575.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: Z129979
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    IUPAC Name
    cyclopentyl N-[3-[[2-methoxy-4-[(2-methylphenyl)sulfonylcarbamoyl]phenyl]methyl]-1-methylindol-5-yl]carbamate
    SMILES
    CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
    InChIKey
    YEEZWCHGZNKEEK-UHFFFAOYSA-N
    InChI
    1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-show more
    Synonyms
    SR-01000759386-9 | ZAFIRLUKAST [MI] | AB00639922_09 | cyclopentyl N-[3-[[2-methoxy-4-(o-tolylsulfonylcarbamoyl)phenyl...
  2. ZM 336372, Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
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    ZM 336372, Inhibitor of Raf-1 proto-oncogene; serine/threonine kinase
    CAS: 208260-29-1 EC Number: 106-467-8 PubChem CID: 5730 Formula: C23H23N3O3 Molecular Weight: 389.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: Z129624
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    IUPAC Name
    3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
    InChIKey
    PYEFPDQFAZNXLI-UHFFFAOYSA-N
    InChI
    1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28)
    Synonyms
    Bio1_001346 | Q27089299 | BiomolKI2_000059 | KBioSS_000580 | SMR004702983 | NCGC00025109-02 | ZINC00581684 | Benzamid...
  3. 3,4-Dihydro-2(1H)-quinolinone
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    3,4-Dihydro-2(1H)-quinolinone
    CAS: 553-03-7 EC Number: 621-863-5 Formula: C9H9NO Molecular Weight: 147.18
    ≥97.5%
    In Stock Item #: D336131
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    IUPAC Name
    3,4-dihydro-1H-quinolin-2-one
    SMILES
    C1CC(=O)NC2=CC=CC=C21
    InChIKey
    TZOYXRMEFDYWDQ-UHFFFAOYSA-N
    InChI
    1S/C9H9NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-4H,5-6H2,(H,10,11)
    Synonyms
    2-Oxo-1,3,4-tetrahydroquinoline | 2(1H)-Quinolinone, 3,4-dihydro- | STR08974 | 3,4-Dihydro-2(1H)quinolinone | 3,4-Dih...
  4. SB-505124 hydrochloride
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    SB-505124 hydrochloride
    CAS: 356559-13-2 PubChem CID: 16079009 Formula: C20H21N3O2HCl Molecular Weight: 371.86
    ≥97%
    In Stock Item #: T334804
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    IUPAC Name
    2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine;hydrochloride
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4.Cl
    InChIKey
    BTUOOXPZOVNPMF-UHFFFAOYSA-N
    InChI
    1S/C20H21N3O2.ClH/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15;/h5-10H,11H2,1-4H3,(H,22,23);1H
    Synonyms
    2-(5-benzo[1,3]dioxol-5-yl-2-tert-butyl-3h-imidazol-4-yl)-6-methylpyridine hydrochloride | BCP19172 | SCHEMBL140197 |...
  5. GW788388
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    GW788388
    CAS: 452342-67-5 Formula: C25H23N5O2 Molecular Weight: 425.48
    ≥98%
    In Stock Item #: G125999
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    IUPAC Name
    N-(oxan-4-yl)-4-[4-(5-pyridin-2-yl-1H-pyrazol-4-yl)pyridin-2-yl]benzamide
    SMILES
    C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5
    InChIKey
    SAGZIBJAQGBRQA-UHFFFAOYSA-N
    InChI
    1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2show more
    Synonyms
    FT-0700309 | HMS3656N21 | UNII-N14114957J | Q27284368 | N-(oxan-4-yl)-4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-...
  6. AG-1478 (Tyrphostin AG-1478)
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    AG-1478 (Tyrphostin AG-1478)
    CAS: 153436-53-4 EC Number: 640-463-1 Formula: C16H14ClN3O2 Molecular Weight: 315.75
    ≥98%
    In Stock Item #: A126582
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    IUPAC Name
    N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
    SMILES
    COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
    InChIKey
    GFNNBHLJANVSQV-UHFFFAOYSA-N
    InChI
    1S/C16H14ClN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)
    Synonyms
    AG 1478 | HY-13524 | Tyrphostin AG-1478;NSC 693255 | Bio1_001322 | EX-A1236 | Maybridge1_004001 | HMS3229O03 | Tox21_...
  7. SB505124, Inhibitor of transforming growth factor beta receptor 1
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    SB505124, Inhibitor of transforming growth factor beta receptor 1
    CAS: 694433-59-5 PubChem CID: 9858940 Formula: C20H21N3O2 Molecular Weight: 335.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S126125
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    IUPAC Name
    2-[4-(1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
    SMILES
    CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4
    InChIKey
    WGZOTBUYUFBEPZ-UHFFFAOYSA-N
    InChI
    1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23)
    Synonyms
    HMS3655F08 | SCHEMBL373422 | AS-74679 | amino-4,6-dimethoxypyrimidine | CCG-267861 | TGF-beta RI Inhibitor III | etho...
  8. Pirfenidone - Moligand™, ≥98%(GC) CAS No(53179-13-8) by Aladdin Scientific
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    Pirfenidone
    CAS: 53179-13-8 EC Number: 621-260-7 Formula: C12H11NO Molecular Weight: 185.22
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(GC)
    In Stock Item #: P129335
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    IUPAC Name
    5-methyl-1-phenylpyridin-2-one
    SMILES
    CC1=CN(C(=O)C=C1)C2=CC=CC=C2
    InChIKey
    ISWRGOKTTBVCFA-UHFFFAOYSA-N
    InChI
    1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
    Synonyms
    MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone ...
  9. Benzbromarone
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    Benzbromarone
    CAS: 3562-84-3 EC Number: 222-630-7 Formula: C17H12Br2O3 Molecular Weight: 424.08
    ≥98%(HPLC)
    In Stock Item #: B131634
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    Technical Identifiers
    IUPAC Name
    (3,5-dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
    SMILES
    CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br
    InChIKey
    WHQCHUCQKNIQEC-UHFFFAOYSA-N
    InChI
    1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
    Synonyms
    MJ 10061 | Prestwick3_000370 | SPBio_002420 | CPD000058310 | NCGC00013895-08 | Prestwick0_000370 | 3,5-Dibromo-4-hydr...
  10. PH-797804, MAP kinase p38 alpha inhibitor
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    PH-797804, MAP kinase p38 alpha inhibitor
    CAS: 586379-66-0 EC Number: 110-020-2 Formula: C22H19BrF2N2O3 Molecular Weight: 477.3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P127738
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    IUPAC Name
    3-[3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxopyridin-1-yl]-N,4-dimethylbenzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C
    InChIKey
    KCAJXIDMCNPGHZ-UHFFFAOYSA-N
    InChI
    1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)
    Synonyms
    SMR004702814 | C74360 | PH-797804, >=98% (HPLC) | PH-797804, (AXIAL S)-(-)- | UNII-SI09I1V827 | 1358027-80-1 | CCG-35...
  11. U0126
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    U0126
    CAS: 109511-58-2 PubChem CID: 3006531 Formula: C18H16N6S2 Molecular Weight: 380.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: U274745
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    IUPAC Name
    (2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile
    SMILES
    C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
    InChIKey
    DVEXZJFMOKTQEZ-JYFOCSDGSA-N
    InChI
    1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+
    Synonyms
    1,4-Diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene | bis[Amino[(2-aminophenyl)thio]methylene]-butanedinitril...
  12. SB-203580, Inhibitor of cyclin G associated kinase;Inhibitor of mitogen-activated protein kinase 11;Inhibitor of mitogen-activated protein kinase 14
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    SB-203580, Inhibitor of cyclin G associated kinase;Inhibitor of mitogen-activated protein kinase 11;Inhibitor of mitogen-activated protein kinase 14
    CAS: 152121-47-6 EC Number: 688-252-3 PubChem CID: 176155 Formula: C21H16FN3OS Molecular Weight: 377.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S131899
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    IUPAC Name
    4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
    SMILES
    CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F
    InChIKey
    CDMGBJANTYXAIV-UHFFFAOYSA-N
    InChI
    1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)
    Synonyms
    ES-0013 | RWJ64809 | RWJ-64809 | CHEBI:90705 | UNII-OU13V1EYWQ | J-008891 | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfiny...
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