Myosin light chain kinase family member 4 (MYLK4)

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  1. 11-(3-(Dimethylamino)prop-1-yn-1-yl)-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohepta[1,2-b]indol-2-amine, Inhibitor of myosin light chain kinase family member 4;Inhibitor of phosphoinositide kinase; FYVE-type zinc finger containing
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: D608800
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    IUPAC Name
    11-(3-(Dimethylamino)prop-1-yn-1-yl)-5,6,7,8-tetrahydropyrimido[4′,5′:3,4]cyclohepta[1,2-b]indol-2-amine
    SMILES
    Nc1ncc2CCCc3c(c2n1)c1c([nH]3)ccc(c1)C#CCN(C)C
    InChIKey
    DORZPJWJOBMQKC-UHFFFAOYSA-N
    InChI
    1S/C20H21N5/c1-25(2)10-4-5-13-8-9-16-15(11-13)18-17(23-16)7-3-6-14-12-22-20(21)24-19(14)18/h8-9,11-12,23H,3,6-7,10H2,1-2H3,(H2,21,22,24)
    Synonyms
    compound 17
  2. netarsudil, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2
    CAS: 1254032-66-0 EC Number: 817-239-9 PubChem CID: 66599893
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N612224
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    IUPAC Name
    [4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate
    SMILES
    CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)C(CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C
    InChIKey
    OURRXQUGYQRVML-AREMUKBSSA-N
    InChI
    1S/C28H27N3O3/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24/h3-14,16,26H,15,17,29H2,1-2H3,show more
    Synonyms
    Netarsudil | NETARSUDIL [MI] | UNII-W6I5QDT7QI | NETARSUDIL [WHO-DD] | SCHEMBL16036278 | BDBM50546247 | Q27292390 | B...
  3. Netarsudil
    CAS: 1254032-66-0 EC Number: 817-239-9 PubChem CID: 66599893
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: N1495842
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