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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG)

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  1. GSK2126458 (GSK458), Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
    Wish List Compare
    GSK2126458 (GSK458), Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
    CAS: 1086062-66-9 EC Number: 629-873-1 Formula: C25H17F2N5O3S Molecular Weight: 505.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G127233
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    IUPAC Name
    2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide
    SMILES
    COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F
    InChIKey
    CGBJSGAELGCMKE-UHFFFAOYSA-N
    InChI
    1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3
    Synonyms
    A25172 | CHEBI:95093 | HMS3656D09 | N-[2-Methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide | ...
  2. ZSTK474, PI3-kinase class I inhibitor
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    ZSTK474, PI3-kinase class I inhibitor
    CAS: 475110-96-4 PubChem CID: 11647372 Formula: C19H21F2N7O2 Molecular Weight: 417.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: Z126804
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    IUPAC Name
    4-[4-[2-(difluoromethyl)benzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine
    SMILES
    C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5
    InChIKey
    HGVNLRPZOWWDKD-UHFFFAOYSA-N
    InChI
    1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
    Synonyms
    BRD-K63068307-001-01-4 | TCMDC-137004 | 4,4''-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diy...
  3. PKI-402
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    PKI-402
    CAS: 1173204-81-3 Formula: C29H34N10O3 Molecular Weight: 570.65
    Solid ≥98%
    Out of Stock Item #: P127674
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    Technical Identifiers
    IUPAC Name
    1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-[4-(4-methylpiperazine-1-carbonyl)phenyl]urea
    SMILES
    CCN1C2=C(C(=NC(=N2)C3=CC=C(C=C3)NC(=O)NC4=CC=C(C=C4)C(=O)N5CCN(CC5)C)N6CCOCC6)N=N1
    InChIKey
    ZAXFYGBKZSQBIV-UHFFFAOYSA-N
    InChI
    1S/C29H34N10O3/c1-3-39-27-24(34-35-39)26(37-16-18-42-19-17-37)32-25(33-27)20-4-8-22(9-5-20)30-29(41)31-23-10-6-21(7-11-23)28(40)38-14-12-36(2)13-15-38show more
    Synonyms
    BDBM50308767 | MS-30305 | STL453648 | PKI402 | N-(4-(3-Ethyl-7-(4-morpholinyl)-3H-1,2,3-triazolo(4,5-d)pyrimidin-5-yl...
  4. TC KHNS 11 - ≥95% CAS No(1431540-99-6) by Aladdin Scientific
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    TC KHNS 11
    CAS: 1431540-99-6 PubChem CID: 86732669 Formula: C28H24N6O3 Molecular Weight: 492.53
    ≥95%
    Out of Stock Item #: T287117
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    IUPAC Name
    5-[4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl]-2-methoxypyridine-3-carbonitrile
    SMILES
    CC(=O)N1CCN(CC1)C(=O)C2=CC=CC(=C2)C3=NC=NC4=C3C=C(C=C4)C5=CC(=C(N=C5)OC)C#N
    InChIKey
    QYTXJLQBSYAMGR-UHFFFAOYSA-N
    InChI
    1S/C28H24N6O3/c1-18(35)33-8-10-34(11-9-33)28(36)21-5-3-4-20(12-21)26-24-14-19(6-7-25(24)31-17-32-26)23-13-22(15-29)27(37-2)30-16-23/h3-7,12-14,16-17H,show more
    Synonyms
    5-[4-[3-[(4-Acetyl-1-piperazinyl)carbonyl]phenyl]-6-quinazolinyl]-2-methoxy-3-pyridinecarbonitrile
  5. PKI-179, PI3-kinase p110-alpha subunit inhibitor
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    PKI-179, PI3-kinase p110-alpha subunit inhibitor
    CAS: 1197160-28-3 PubChem CID: 46947264 Formula: C25H28N8O3 Molecular Weight: 488.54
    ≥98%
    In Stock Item #: P345208
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    Technical Identifiers
    IUPAC Name
    1-[4-[4-morpholin-4-yl-6-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-1,3,5-triazin-2-yl]phenyl]-3-pyridin-4-ylurea
    SMILES
    C1CC2COCC1N2C3=NC(=NC(=N3)N4CCOCC4)C5=CC=C(C=C5)NC(=O)NC6=CC=NC=C6
    InChIKey
    WXUUCRLKXQMWRY-UHFFFAOYSA-N
    InChI
    1S/C25H28N8O3/c34-25(28-19-7-9-26-10-8-19)27-18-3-1-17(2-4-18)22-29-23(32-11-13-35-14-12-32)31-24(30-22)33-20-5-6-21(33)16-36-15-20/h1-4,7-10,20-21H,5show more
    Synonyms
    PKI-179 | 1-{4-[4-morpholin-4-yl-6-(3-oxa-8-azabicyclo[3.2.1]oct-8-yl)-1,3,5-triazin-2-yl]phenyl}-3-pyridin-4-ylurea ...
  6. PIK-75
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    PIK-75
    CAS: 372196-77-5 PubChem CID: 45265864 Formula: C16H14BrN5O4S·HCl Molecular Weight: 488.74
    ≥98%
    In Stock Item #: P125966
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    Technical Identifiers
    IUPAC Name
    N-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide;hydrochloride
    SMILES
    CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)N=CC2=CN=C3N2C=C(C=C3)Br.Cl
    InChIKey
    VOUDEIAYNKZQKM-MYHMWQFYSA-N
    InChI
    1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
    Synonyms
    (E)-N'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride | (E)...
  7. 6-Chloro-1,3-benzoxazol-2-amine
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    6-Chloro-1,3-benzoxazol-2-amine
    CAS: 52112-68-2 Formula: C7H5ClN2O Molecular Weight: 168.58
    ≥97%
    In Stock Item #: C193728
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    Technical Identifiers
    IUPAC Name
    6-chloro-1,3-benzoxazol-2-amine
    SMILES
    C1=CC2=C(C=C1Cl)OC(=N2)N
    InChIKey
    QDMXVLGVKMTTIT-UHFFFAOYSA-N
    InChI
    1S/C7H5ClN2O/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H2,9,10)
    Synonyms
    2-Benzoxazolamine, 6-chloro- | 6-Chloro-2-benzoxazolamine | BENZOXAZOLE, 2-AMINO-6-CHLORO- | 2-Amino-6-chlorobenzoxaz...
  8. PI-3065, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
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    PI-3065, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta
    CAS: 955977-50-1 PubChem CID: 24937012 Formula: C27H31FN6OS Molecular Weight: 506.64
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: P288892
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    IUPAC Name
    4-[6-[[4-(cyclopropylmethyl)piperazin-1-yl]methyl]-2-(5-fluoro-1H-indol-4-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine
    SMILES
    C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7
    InChIKey
    YDNOHCOYQVZOMC-UHFFFAOYSA-N
    InChI
    1S/C27H31FN6OS/c28-21-3-4-22-20(5-6-29-22)24(21)26-30-23-15-19(17-33-9-7-32(8-10-33)16-18-1-2-18)36-25(23)27(31-26)34-11-13-35-14-12-34/h3-6,15,18,29Hshow more
    Synonyms
    6-[[4-(Cyclopropylmethyl)-1-piperazinyl]methyl]-2-(5-fluoro-1H-indol-4-yl)-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine
  9. PI-103, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
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    PI-103, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
    CAS: 371935-74-9 Formula: C19H16N4O3 Molecular Weight: 348.36
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P125961
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    Technical Identifiers
    IUPAC Name
    3-(6-morpholin-4-yl-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-yl)phenol
    SMILES
    C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
    InChIKey
    TUVCWJQQGGETHL-UHFFFAOYSA-N
    InChI
    1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2
    Synonyms
    GTPL5701 | PI 103 hydrobromide | 3-(4-(4-morpholinyl)pyrido[3?,2?:4,5]furo[3,2-d]pyrimidin-2- yl)phenol | 3-(4-morpho...
  10. PIK-294
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    PIK-294
    CAS: 900185-02-6 EC Number: 110-148-9 Formula: C28H23N7O2 Molecular Weight: 489.53
    ≥98%
    In Stock Item #: P129553
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    Technical Identifiers
    IUPAC Name
    2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one
    SMILES
    CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C(=N4)C6=CC(=CC=C6)O)N
    InChIKey
    WFSLJOPRIJSOJR-UHFFFAOYSA-N
    InChI
    1S/C28H23N7O2/c1-16-7-3-4-12-21(16)35-22(32-20-11-5-8-17(2)23(20)28(35)37)14-34-27-24(26(29)30-15-31-27)25(33-34)18-9-6-10-19(36)13-18/h3-13,15,36H,14show more
    Synonyms
    HMS3244F13 | HMS3655P12 | 2-{[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-meth...
  11. INK 128 (MLN0128), Serine/threonine-protein kinase mTOR inhibitor
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    INK 128 (MLN0128), Serine/threonine-protein kinase mTOR inhibitor
    CAS: 1224844-38-5 Formula: C15H15N7O Molecular Weight: 309.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: I128086
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    IUPAC Name
    5-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine
    SMILES
    CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N
    InChIKey
    GYLDXIAOMVERTK-UHFFFAOYSA-N
    InChI
    1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
    Synonyms
    2-Benzoxazolamine, 5-(4-amino-1-(1-methylethyl)-1H-pyrazolo(3,4-d)pyrimidin-3-yl)- | 3-(2-aminobenzo[d]oxazol-5-yl)-1...
  12. KU-55933 (ATM Kinase Inhibitor), Inhibitor of ATM serine/threonine kinase
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    KU-55933 (ATM Kinase Inhibitor), Inhibitor of ATM serine/threonine kinase
    CAS: 587871-26-9 Formula: C21H17NO3S2 Molecular Weight: 395.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K126884
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    IUPAC Name
    2-morpholin-4-yl-6-thianthren-1-ylpyran-4-one
    SMILES
    C1COCCN1C2=CC(=O)C=C(O2)C3=C4C(=CC=C3)SC5=CC=CC=C5S4
    InChIKey
    XRKYMMUGXMWDAO-UHFFFAOYSA-N
    InChI
    1S/C21H17NO3S2/c23-14-12-16(25-20(13-14)22-8-10-24-11-9-22)15-4-3-7-19-21(15)27-18-6-2-1-5-17(18)26-19/h1-7,12-13H,8-11H2
    Synonyms
    KU-55933, >=98% (HPLC) | 2-Morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | ATM Kinase Inhibitor | HMS3265N15 | HMS3413...
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