Serine/threonine-protein kinase 17b (STK17B)

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  1. KW-2449, Tyrosine-protein kinase ABL inhibitor
    CAS: 1000669-72-6 Formula: C20H20N4O Molecular Weight: 332.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K127169
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    IUPAC Name
    [4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone
    SMILES
    C1CN(CCN1)C(=O)C2=CC=C(C=C2)C=CC3=NNC4=CC=CC=C43
    InChIKey
    YYLKKYCXAOBSRM-JXMROGBWSA-N
    InChI
    1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+
    Synonyms
    (E)-1-{4-[2-(1H-indazol-3-yl)vinyl]benzoyl}piperazine | NCGC00346569-07 | (E)-(4-(2-(1H-Indazol-3-yl)vinyl)-phenyl)(p...
  2. MLN8054, Serine/threonine-protein kinase Aurora-A inhibitor
    CAS: 869363-13-3 Formula: C25H15ClF2N4O2 Molecular Weight: 476.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: M127875
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    IUPAC Name
    4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid
    SMILES
    C1C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)C(=N1)C4=C(C=CC=C4F)F)NC5=CC=C(C=C5)C(=O)O
    InChIKey
    HHFBDROWDBDFBR-UHFFFAOYSA-N
    InChI
    1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10,12H,11H2,(H,33,34show more
    Synonyms
    BX854EHD63 | MLN8054 | MLN-8054 | US8853193, 32-40 | J-513180 | Kinome_1204 | s1100 | SMR004700647 | 4-benzyloxy-2(1H...
  3. GSK8612, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of TANK binding kinase 1
    CAS: 2361659-62-1 Formula: C17H17BrF3N7O2S Molecular Weight: 520.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G422771
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    IUPAC Name
    4-[[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
    SMILES
    CC1=NN(C=C1NC2=NC=C(C(=N2)NCC3=CC=C(C=C3)S(=O)(=O)N)Br)CC(F)(F)F
    InChIKey
    FFPHMUIGESPOTK-UHFFFAOYSA-N
    InChI
    1S/C17H17BrF3N7O2S/c1-10-14(8-28(27-10)9-17(19,20)21)25-16-24-7-13(18)15(26-16)23-6-11-2-4-12(5-3-11)31(22,29)30/h2-5,7-8H,6,9H2,1H3,(H2,22,29,30)(H2,show more
    Synonyms
    Benzenesulfonamide,4-​[[[5-​bromo-​2-​[[3-​methyl-​1-​(2,​2,​2-​trifluoroethyl)​-​1H-​pyrazol-​4-​yl]​amino]​-​4-​pyr...
  4. GSK8612, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of TANK binding kinase 1
    CAS: 2361659-62-1 Formula: C17H17BrF3N7O2S Molecular Weight: 520.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G414233
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    Technical Identifiers
    IUPAC Name
    4-[[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide
    SMILES
    CC1=NN(C=C1NC2=NC=C(C(=N2)NCC3=CC=C(C=C3)S(=O)(=O)N)Br)CC(F)(F)F
    InChIKey
    FFPHMUIGESPOTK-UHFFFAOYSA-N
    InChI
    1S/C17H17BrF3N7O2S/c1-10-14(8-28(27-10)9-17(19,20)21)25-16-24-7-13(18)15(26-16)23-6-11-2-4-12(5-3-11)31(22,29)30/h2-5,7-8H,6,9H2,1H3,(H2,22,29,30)(H2,show more
  5. KW-2449, Tyrosine-protein kinase ABL inhibitor
    CAS: 1000669-72-6 Formula: C20H20N4O Molecular Weight: 332.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: K407735
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    Technical Identifiers
    Synonyms
    (E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone
  6. MLN8054, Serine/threonine-protein kinase Aurora-A inhibitor
    CAS: 869363-13-3 Formula: C25H15ClF2N4O2 Molecular Weight: 476.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M409293
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    Technical Identifiers
    Synonyms
    Benzoic acid, 4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-
  7. SKI-V
    CAS: 24418-86-8 PubChem CID: 5793932 Formula: C15H10O4 Molecular Weight: 254.24
    In Stock Item #: S412566
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-1-benzofuran-3-one
    SMILES
    C1=CC=C2C(=C1)C(=O)C(=CC3=CC(=C(C=C3)O)O)O2
    InChIKey
    HCBULGQMULJTCM-ZSOIEALJSA-N
    InChI
    1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8-
    Synonyms
    2-​[(3,​4-​dihydroxyphenyl)​methylene]​-3(2H)​-​Benzofuranone
  8. SKI-V
    CAS: 24418-86-8 PubChem CID: 5793932 Formula: C15H10O4 Molecular Weight: 254.24
    10mM in DMSO
    In Stock Item #: S422825
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-1-benzofuran-3-one
    SMILES
    C1=CC=C2C(=C1)C(=O)C(=CC3=CC(=C(C=C3)O)O)O2
    InChIKey
    HCBULGQMULJTCM-ZSOIEALJSA-N
    InChI
    1S/C15H10O4/c16-11-6-5-9(7-12(11)17)8-14-15(18)10-3-1-2-4-13(10)19-14/h1-8,16-17H/b14-8-
    Synonyms
    3(2H)​-​Benzofuranone,2-​[(3,​4-​dihydroxyphenyl)​methylene]​-
  9. GSK8612, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of TANK binding kinase 1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610731
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    Technical Identifiers
    IUPAC Name
    4-{[(5-bromo-2-{[3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]amino}pyrimidin-4-yl)amino]methyl}benzene-1-sulfonamide
    SMILES
    Brc1cnc(nc1NCc1ccc(cc1)S(=O)(=O)N)Nc1cn(nc1C)CC(F)(F)F
    InChIKey
    FFPHMUIGESPOTK-UHFFFAOYSA-N
    InChI
    1S/C17H17BrF3N7O2S/c1-10-14(8-28(27-10)9-17(19,20)21)25-16-24-7-13(18)15(26-16)23-6-11-2-4-12(5-3-11)31(22,29)30/h2-5,7-8H,6,9H2,1H3,(H2,22,29,30)(H2,show more
  10. Sulfuretin
    CAS: 120-05-8 EC Number: 204-366-4 PubChem CID: 5281295 Formula: C15H10O5 Molecular Weight: 270.24
    Out of Stock Item #: S650000
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    Technical Identifiers
    IUPAC Name
    (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-6-hydroxy-1-benzofuran-3-one
    SMILES
    C1=CC(=C(C=C1C=C2C(=O)C3=C(O2)C=C(C=C3)O)O)O
    InChIKey
    RGNXWPVNPFAADO-NSIKDUERSA-N
    InChI
    1S/C15H10O5/c16-9-2-3-10-13(7-9)20-14(15(10)19)6-8-1-4-11(17)12(18)5-8/h1-7,16-18H/b14-6-
    Synonyms
    3',4',6-TRIHYDROXYBENZALCOUMARANONE | 3(2H)-Benzofuranone, 2-[(3,4-dihydroxyphenyl)methylene]-6-hydroxy-, (2Z)- | HMS...
  11. Sulfuretin
    CAS: 120-05-8 EC Number: 204-366-4 PubChem CID: 5281295 Formula: C15H10O5 Molecular Weight: 270.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: S1499846
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