Serine/threonine-protein kinase nek6 (NEK6)

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  1. Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
    CAS: 608512-97-6 EC Number: 685-966-7 Formula: C13H8N4OS Molecular Weight: 268.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    Out of Stock Item #: I425038
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    Technical Identifiers
    IUPAC Name
    (8Z)-8-(1H-imidazol-5-ylmethylidene)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-one
    SMILES
    C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
    InChIKey
    VFBGXTUGODTSPK-BAQGIRSFSA-N
    InChI
    1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3-
    Synonyms
    PKR-IN-C16 | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one | AKOS025147356 | SCHEMBL9...
  2. Imidazolo-oxindole PKR inhibitor C16, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 2
    CAS: 608512-97-6 EC Number: 685-966-7 Formula: C13H8N4OS Molecular Weight: 268.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C275080
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (8Z)-8-(1H-imidazol-5-ylmethylidene)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-one
    SMILES
    C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
    InChIKey
    VFBGXTUGODTSPK-BAQGIRSFSA-N
    InChI
    1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3-
    Synonyms
    PKR-IN-C16 | 6,8-Dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one | AKOS025147356 | SCHEMBL9...
  3. NMS-P715
    CAS: 1202055-32-0 Formula: C35H39F3N8O3 Molecular Weight: 676.73
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N648450
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    IUPAC Name
    N-(2,6-diethylphenyl)-1-methyl-8-[4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamishow more
    SMILES
    CCC1=C(C(=CC=C1)CC)NC(=O)C2=NN(C3=C2CCC4=CN=C(N=C43)NC5=C(C=C(C=C5)C(=O)NC6CCN(CC6)C)OC(F)(F)F)C
    InChIKey
    JFOAJUGFHDCBJJ-UHFFFAOYSA-N
    InChI
    1S/C35H39F3N8O3/c1-5-20-8-7-9-21(6-2)28(20)42-33(48)30-25-12-10-23-19-39-34(43-29(23)31(25)46(4)44-30)41-26-13-11-22(18-27(26)49-35(36,37)38)32(47)40-show more
    Synonyms
    MPS1 Inhibitor | NMS-P715 | (N-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromet...
  4. NEK6 inibitor 8
    CAS: 591239-68-8 PubChem CID: 2275754
    Out of Stock Item #: N769774
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    Technical Identifiers
    IUPAC Name
    (5Z)-4-methyl-2,6-dioxo-5-[(5-phenylfuran-2-yl)methylidene]pyridine-3-carbonitrile
    SMILES
    CC1=C(C(=O)NC(=O)C1=CC2=CC=C(O2)C3=CC=CC=C3)C#N
    InChIKey
    SNLNUUWCOAPJED-ZROIWOOFSA-N
    InChI
    1S/C18H12N2O3/c1-11-14(17(21)20-18(22)15(11)10-19)9-13-7-8-16(23-13)12-5-3-2-4-6-12/h2-9H,1H3,(H,20,21,22)/b14-9-
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