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Serine/threonine-protein kinase sik2 (SIK2)

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  1. BMS-690514, Receptor protein-tyrosine kinase erbB-4 inhibitor
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    BMS-690514, Receptor protein-tyrosine kinase erbB-4 inhibitor
    CAS: 859853-30-8 Formula: C19H24N6O2 Molecular Weight: 368.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: B127024
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    IUPAC Name
    (3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol
    SMILES
    COC1=CC=CC(=C1)NC2=NC=NN3C2=C(C=C3)CN4CCC(C(C4)O)N
    InChIKey
    CSGQVNMSRKWUSH-IAGOWNOFSA-N
    InChI
    1S/C19H24N6O2/c1-27-15-4-2-3-14(9-15)23-19-18-13(5-8-25(18)22-12-21-19)10-24-7-6-16(20)17(26)11-24/h2-5,8-9,12,16-17,26H,6-7,10-11,20H2,1H3,(H,21,22,2show more
    Synonyms
    (3R,4R)-4-amino-1-((4-(3-methoxyphenylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-3-ol | BCP9000434 | (3...
  2. ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421945
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    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  3. ARN-3236 - Moligand™, ≥98%, CAS No. 1613710-01-2 by
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A414050
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  4. AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
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    AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
    CAS: 860352-01-8 EC Number: 804-400-3 Formula: C17H19FN4O2S Molecular Weight: 362.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A408077
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    Technical Identifiers
    Synonyms
    1-(2-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophenyl)thiophen-3-yl)urea
  5. AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
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    AZD7762, Serine/threonine-protein kinase Chk1 inhibitor
    CAS: 860352-01-8 EC Number: 804-400-3 Formula: C17H19FN4O2S Molecular Weight: 362.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A127862
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    Technical Identifiers
    IUPAC Name
    3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
    SMILES
    C1CC(CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
    InChIKey
    IAYGCINLNONXHY-LBPRGKRZSA-N
    InChI
    1S/C17H19FN4O2S/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24)/t12-/m0show more
    Synonyms
    5D822Y3L1H | H1206 | 4,4'-DIMETHOXYTHIOCARBANILIDE | BS-22319 | C17H19FN4O2S | CCG-264907 | J-502468 | AZD 7762 | BDB...
  6. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: H421682
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    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  7. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: H413999
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    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  8. MK-8776 (SCH 900776), Serine/threonine-protein kinase Chk1 inhibitor
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    MK-8776 (SCH 900776), Serine/threonine-protein kinase Chk1 inhibitor
    CAS: 891494-63-6 PubChem CID: 46239015 Formula: C15H18BrN7 Molecular Weight: 376.25
    ≥98%
    In Stock Item #: S127483
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    Technical Identifiers
    IUPAC Name
    6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    SMILES
    CN1C=C(C=N1)C2=C3N=C(C(=C(N3N=C2)N)Br)C4CCCNC4
    InChIKey
    GMIZZEXBPRLVIV-SECBINFHSA-N
    InChI
    1S/C15H18BrN7/c1-22-8-10(6-19-22)11-7-20-23-14(17)12(16)13(21-15(11)23)9-3-2-4-18-5-9/h6-9,18H,2-5,17H2,1H3/t9-/m1/s1
    Synonyms
    (R)-6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine | NSC800880 | NSC-800880 ...
  10. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    10mM in DMSO
    In Stock Item #: Y422363
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    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,3-​(2-​chloro-​6-​methylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-​(1-​met...
  11. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    ≥98%
    In Stock Item #: Y414441
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    Technical Identifiers
    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5...
  12. no_selection
    Wish List Compare
    GLPG3970, Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610582
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    IUPAC Name
    8-methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one
    SMILES
    COc1cc(cc2c1C(=O)N(CC2)CC(F)(F)F)c1cnc2n1ccc(c2)OCCN1CCOCC1
    InChIKey
    XASOHFCUIQARJT-UHFFFAOYSA-N
    InChI
    1S/C25H27F3N4O4/c1-34-21-13-18(12-17-2-4-31(16-25(26,27)28)24(33)23(17)21)20-15-29-22-14-19(3-5-32(20)22)36-11-8-30-6-9-35-10-7-30/h3,5,12-15H,2,4,6-1show more
    Synonyms
    GTPL12157 | XASOHFCUIQARJT-UHFFFAOYSA-N | 8-Methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2...
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