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Serine/threonine-protein kinase sik3 (SIK3)

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  1. PX-866, PI3-kinase class I inhibitor
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    PX-866, PI3-kinase class I inhibitor
    CAS: 502632-66-8 EC Number: 812-171-6 PubChem CID: 9849735 Formula: C29H35NO8 Molecular Weight: 525.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: P274838
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    Technical Identifiers
    IUPAC Name
    [(3aR,6E,9S,9aR,10R,11aS)-6-[[bis(prop-2-enyl)amino]methylidene]-5-hydroxy-9-(methoxymethyl)-9a,11a-dimethyl-1,4,7-trioxo-2,3,3a,9,10,11-hexahydroindeshow more
    SMILES
    CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN(CC=C)CC=C)C4=C(C3=O)O)COC)C)C
    InChIKey
    QIUASFSNWYMDFS-NILGECQDSA-N
    InChI
    1S/C29H35NO8/c1-7-11-30(12-8-2)14-17-23-26(34)25(33)22-18-9-10-20(32)28(18,4)13-19(37-16(3)31)24(22)29(23,5)21(15-36-6)38-27(17)35/h7-8,14,18-19,21,34show more
    Synonyms
    PX 866 | QIUASFSNWYMDFS-NILGECQDSA-N | DB12601 | AKOS040742638 | Sonolisib [INN] | BP162743 | AKOS001660076 | [(3aR,6...
  2. ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421945
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    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  3. ARN-3236 - Moligand™, ≥98%, CAS No. 1613710-01-2 by
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A414050
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  4. Crenolanib (CP-868596), Tyrosine-protein kinase receptor FLT3 inhibitor
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    Crenolanib (CP-868596), Tyrosine-protein kinase receptor FLT3 inhibitor
    CAS: 670220-88-9 Formula: C26H29N5O2 Molecular Weight: 443.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: C409050
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    Synonyms
    ARO 002 | 1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
  5. Crenolanib (CP-868596), Tyrosine-protein kinase receptor FLT3 inhibitor
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    Crenolanib (CP-868596), Tyrosine-protein kinase receptor FLT3 inhibitor
    CAS: 670220-88-9 Formula: C26H29N5O2 Molecular Weight: 443.54
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C127776
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    IUPAC Name
    1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine
    SMILES
    CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4
    InChIKey
    DYNHJHQFHQTFTP-UHFFFAOYSA-N
    InChI
    1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,2show more
    Synonyms
    ETHYL .ALPHA.-AMINOPHENYLACETATE | AKOS026750597 | Crenolanib [USAN] | 6T2 | AS-57698 | CP-868596 (Crenolanib) | CREN...
  6. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: H421682
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    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  7. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    Wish List Compare
    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: H413999
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    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  8. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    10mM in DMSO
    In Stock Item #: Y422363
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    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,3-​(2-​chloro-​6-​methylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-​(1-​met...
  9. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    ≥98%
    In Stock Item #: Y414441
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    Technical Identifiers
    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5...
  10. no_selection
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    GLPG3970, Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610582
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    IUPAC Name
    8-methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one
    SMILES
    COc1cc(cc2c1C(=O)N(CC2)CC(F)(F)F)c1cnc2n1ccc(c2)OCCN1CCOCC1
    InChIKey
    XASOHFCUIQARJT-UHFFFAOYSA-N
    InChI
    1S/C25H27F3N4O4/c1-34-21-13-18(12-17-2-4-31(16-25(26,27)28)24(33)23(17)21)20-15-29-22-14-19(3-5-32(20)22)36-11-8-30-6-9-35-10-7-30/h3,5,12-15H,2,4,6-1show more
    Synonyms
    GTPL12157 | XASOHFCUIQARJT-UHFFFAOYSA-N | 8-Methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2...
  11. GLPG3970
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    GLPG3970
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: G1497670
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  12. Sonolisib
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    Sonolisib
    CAS: 502632-66-8 EC Number: 812-171-6 PubChem CID: 9849735 Formula: C29H35NO8 Molecular Weight: 525.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: S1499988
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