Serine/threonine-protein kinase ulk2 (ULK2)

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  1. MRT67307, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of TANK binding kinase 1
    CAS: 1190378-57-4 Formula: C26H36N6O2 Molecular Weight: 464.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M126461
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    IUPAC Name
    N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
    SMILES
    C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5
    InChIKey
    UKBGBACORPRCGG-UHFFFAOYSA-N
    InChI
    1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1,4,7,16-17,20-21H,2-3,5-6show more
    Synonyms
    BS-14599 | NCGC00163978-01 | AKOS030526302 | N-{3-[(5-Cyclopropyl-2-{[3-(Morpholin-4-Ylmethyl)phenyl]amino}pyrimidin-...
  2. MRT67307, Inhibitor of inhibitor of nuclear factor kappa B kinase subunit epsilon;Inhibitor of TANK binding kinase 1
    CAS: 1190378-57-4 Formula: C26H36N6O2 Molecular Weight: 464.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M420841
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    Technical Identifiers
    IUPAC Name
    N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide
    SMILES
    C1CC(C1)C(=O)NCCCNC2=NC(=NC=C2C3CC3)NC4=CC=CC(=C4)CN5CCOCC5
    InChIKey
    UKBGBACORPRCGG-UHFFFAOYSA-N
    InChI
    1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1,4,7,16-17,20-21H,2-3,5-6show more
    Synonyms
    BS-14599 | NCGC00163978-01 | AKOS030526302 | N-{3-[(5-Cyclopropyl-2-{[3-(Morpholin-4-Ylmethyl)phenyl]amino}pyrimidin-...
  3. SBI-0206965, Inhibitor of unc-51 like autophagy activating kinase 1
    CAS: 1884220-36-3 EC Number: 861-948-6 PubChem CID: 92044402 Formula: C21H21BrN4O5 Molecular Weight: 489.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S413863
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    IUPAC Name
    2-[5-bromo-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]oxy-N-methylbenzamide
    SMILES
    CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC
    InChIKey
    NEXGBSJERNQRSV-UHFFFAOYSA-N
    InChI
    1S/C21H21BrN4O5/c1-23-19(27)13-7-5-6-8-15(13)31-20-14(22)11-24-21(26-20)25-12-9-16(28-2)18(30-4)17(10-12)29-3/h5-11H,1-4H3,(H,23,27)(H,24,25,26)
    Synonyms
    AS-56287 | GTPL11339 | 2-(5-Bromo-2-(3,4,5-trimethoxyphenylamino)pyrimidin-4-yloxy)-N-methylbenzamide | 4-oxocyclohex...
  4. SBI-0206965, Inhibitor of unc-51 like autophagy activating kinase 1
    CAS: 1884220-36-3 EC Number: 861-948-6 PubChem CID: 92044402 Formula: C21H21BrN4O5 Molecular Weight: 489.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S422306
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    Technical Identifiers
    IUPAC Name
    2-[5-bromo-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]oxy-N-methylbenzamide
    SMILES
    CNC(=O)C1=CC=CC=C1OC2=NC(=NC=C2Br)NC3=CC(=C(C(=C3)OC)OC)OC
    InChIKey
    NEXGBSJERNQRSV-UHFFFAOYSA-N
    InChI
    1S/C21H21BrN4O5/c1-23-19(27)13-7-5-6-8-15(13)31-20-14(22)11-24-21(26-20)25-12-9-16(28-2)18(30-4)17(10-12)29-3/h5-11H,1-4H3,(H,23,27)(H,24,25,26)
    Synonyms
    SBI-0206965|1884220-36-3|Sbi0206965|2-((5-Bromo-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamid...
  5. SBP-7455, Inhibitor of unc-51 like autophagy activating kinase 1;Inhibitor of unc-51 like autophagy activating kinase 2
    CAS: 1884222-74-5 PubChem CID: 132178569 Formula: C16H17F3N4O2 Molecular Weight: 354.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: S412916
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    IUPAC Name
    4-N-cyclopropyl-2-N-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine
    SMILES
    COC1=C(C=C(C=C1)NC2=NC=C(C(=N2)NC3CC3)C(F)(F)F)OC
    InChIKey
    BQROJYIEHOOQBY-UHFFFAOYSA-N
    InChI
    1S/C16H17F3N4O2/c1-24-12-6-5-10(7-13(12)25-2)22-15-20-8-11(16(17,18)19)14(23-15)21-9-3-4-9/h5-9H,3-4H2,1-2H3,(H2,20,21,22,23)
    Synonyms
    2,​4-​Pyrimidinediamine,N4-​cyclopropyl-​N2-​(3,​4-​dimethoxyphenyl)​-​5-​(trifluoromethyl)​-
  6. SBP-7455, Inhibitor of unc-51 like autophagy activating kinase 1;Inhibitor of unc-51 like autophagy activating kinase 2
    CAS: 1884222-74-5 PubChem CID: 132178569 Formula: C16H17F3N4O2 Molecular Weight: 354.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S422307
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    4-N-cyclopropyl-2-N-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine
    SMILES
    COC1=C(C=C(C=C1)NC2=NC=C(C(=N2)NC3CC3)C(F)(F)F)OC
    InChIKey
    BQROJYIEHOOQBY-UHFFFAOYSA-N
    InChI
    1S/C16H17F3N4O2/c1-24-12-6-5-10(7-13(12)25-2)22-15-20-8-11(16(17,18)19)14(23-15)21-9-3-4-9/h5-9H,3-4H2,1-2H3,(H2,20,21,22,23)
    Synonyms
    2,​4-​Pyrimidinediamine,N4-​cyclopropyl-​N2-​(3,​4-​dimethoxyphenyl)​-​5-​(trifluoromethyl)​-
  7. ULK-101
    CAS: 2443816-45-1 PubChem CID: 137628686 Formula: C22H16F4N4OS Molecular Weight: 460.45
    In Stock Item #: U414186
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    Technical Identifiers
    IUPAC Name
    N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-[6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide
    SMILES
    C1CC1C(C(F)(F)F)NC(=O)C2=CC(=CS2)C3=C4N=CC(=CN4N=C3)C5=CC=C(C=C5)F
    InChIKey
    PFZRXJIYAFANHP-IBGZPJMESA-N
    InChI
    1S/C22H16F4N4OS/c23-16-5-3-12(4-6-16)15-8-27-20-17(9-28-30(20)10-15)14-7-18(32-11-14)21(31)29-19(13-1-2-13)22(24,25)26/h3-11,13,19H,1-2H2,(H,29,31)/t1show more
    Synonyms
    (S)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-(6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)thiophene-2-carboxamide
  8. ULK-101
    CAS: 2443816-45-1 PubChem CID: 137628686 Formula: C22H16F4N4OS Molecular Weight: 460.45
    10mM in DMSO
    In Stock Item #: U492048
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]-4-[6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl]thiophene-2-carboxamide
    SMILES
    C1CC1C(C(F)(F)F)NC(=O)C2=CC(=CS2)C3=C4N=CC(=CN4N=C3)C5=CC=C(C=C5)F
    InChIKey
    PFZRXJIYAFANHP-IBGZPJMESA-N
    InChI
    1S/C22H16F4N4OS/c23-16-5-3-12(4-6-16)15-8-27-20-17(9-28-30(20)10-15)14-7-18(32-11-14)21(31)29-19(13-1-2-13)22(24,25)26/h3-11,13,19H,1-2H2,(H,29,31)/t1show more
    Synonyms
    (S)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-(6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)thiophene-2-carboxamide
  9. SBP-7455, Inhibitor of unc-51 like autophagy activating kinase 1;Inhibitor of unc-51 like autophagy activating kinase 2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S613474
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    Technical Identifiers
    IUPAC Name
    N4-cyclopropyl-N2-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine
    SMILES
    COc1cc(ccc1OC)Nc1ncc(c(n1)NC1CC1)C(F)(F)F
    InChIKey
    BQROJYIEHOOQBY-UHFFFAOYSA-N
    InChI
    1S/C16H17F3N4O2/c1-24-12-6-5-10(7-13(12)25-2)22-15-20-8-11(16(17,18)19)14(23-15)21-9-3-4-9/h5-9H,3-4H2,1-2H3,(H2,20,21,22,23)
    Synonyms
    compound 26;SBP7455
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