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Tyrosine-protein kinase fer (FER)

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  1. GSK1904529A
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    GSK1904529A
    CAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G127237
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    IUPAC Name
    N-(2,6-difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yshow more
    SMILES
    CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)S(=O)(=O)C)OC)NC4=NC=CC(=N4)C5=C(N=C6N5C=CC=C6)C7=CC(=C(C=C7)OC)C(=O)NC8=C(C=CC=C8F)F
    InChIKey
    MOSKATHMXWSZTQ-UHFFFAOYSA-N
    InChI
    1S/C44H47F2N9O5S/c1-5-28-26-35(38(60-3)27-36(28)53-19-15-30(16-20-53)52-21-23-54(24-22-52)61(4,57)58)49-44-47-17-14-34(48-44)42-40(50-39-11-6-7-18-55(show more
    Synonyms
    MOSKATHMXWSZTQ-UHFFFAOYSA-N | SB18897 | Trifluralin [ANSI:BSI:ISO] | AMY24202 | A24618 | GSK 4529 | IGF-1R inhibitor ...
  2. TSU-68 (SU6668, Orantinib), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
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    TSU-68 (SU6668, Orantinib), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    CAS: 252916-29-3 PubChem CID: 5329099 Formula: C18H18N2O3 Molecular Weight: 310.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T125079
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    IUPAC Name
    3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
    SMILES
    CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=CC=CC=C3NC2=O
    InChIKey
    NHFDRBXTEDBWCZ-ZROIWOOFSA-N
    InChI
    1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
    Synonyms
    3-{2,4-Dimethyl-5-[(Z)-(2-Oxo-1,2-Dihydro-3h-Indol-3-Ylidene)methyl]-1h-Pyrrol-3-Yl}propanoic Acid | J-502593 | ORANT...
  3. Lorlatinib - Moligand™, ≥98%(HPLC) CAS No(1454846-35-5) P167337 by Aladdin Scientific
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    Lorlatinib, EML4-ALK inhibitor
    CAS: 1454846-35-5 EC Number: 813-704-5 PubChem CID: 71731823 Formula: C21H19FN6O2 Molecular Weight: 406.41
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: P167337
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    IUPAC Name
    (16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carshow more
    SMILES
    CC1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
    InChIKey
    IIXWYSCJSQVBQM-LLVKDONJSA-N
    InChI
    1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/show more
    Synonyms
    (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8-methenopyrazolo(4,3-h)(2,5,11)benzoxad...
  4. Brigatinib, Epidermal growth factor receptor erbB1 inhibitor
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    Brigatinib, Epidermal growth factor receptor erbB1 inhibitor
    CAS: 1197953-54-0 EC Number: 849-234-2 Formula: C29H39ClN7O2P Molecular Weight: 584.09
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B413950
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    IUPAC Name
    5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine
    SMILES
    CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC
    InChIKey
    AILRADAXUVEEIR-UHFFFAOYSA-N
    InChI
    1S/C29H39ClN7O2P/c1-35-15-17-37(18-16-35)21-11-13-36(14-12-21)22-9-10-24(26(19-22)39-2)33-29-31-20-23(30)28(34-29)32-25-7-5-6-8-27(25)40(3,4)38/h5-10,show more
    Synonyms
    1197953-54-0 | NCGC00483924-01 | (2-((5-chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino...
  5. Brigatinib (AP26113), Epidermal growth factor receptor erbB1 inhibitor
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    Brigatinib (AP26113), Epidermal growth factor receptor erbB1 inhibitor
    CAS: 1197953-54-0 EC Number: 849-234-2 Formula: C29H39ClN7O2P Molecular Weight: 584.09
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 2mM in DMSO
    In Stock Item #: B420874
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    IUPAC Name
    5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidine-2,4-diamine
    SMILES
    CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC
    InChIKey
    AILRADAXUVEEIR-UHFFFAOYSA-N
    InChI
    1S/C29H39ClN7O2P/c1-35-15-17-37(18-16-35)21-11-13-36(14-12-21)22-9-10-24(26(19-22)39-2)33-29-31-20-23(30)28(34-29)32-25-7-5-6-8-27(25)40(3,4)38/h5-10,show more
    Synonyms
    1197953-54-0 | NCGC00483924-01 | (2-((5-chloro-2-((2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino...
  6. GSK1904529A
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    GSK1904529A
    CAS: 1089283-49-7 Formula: C44H47F2N9O5S Molecular Weight: 851.96
    10mM in DMSO
    In Stock Item #: G407786
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    Pricing & Pack Sizes
    Technical Identifiers
    Synonyms
    GSK 4529 | N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-4-(4-(4-(methylsulfonyl)piperazin-1-yl)piperidin-1-yl)ph...
  7. Lorlatinib (PF-6463922), EML4-ALK inhibitor
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    Lorlatinib (PF-6463922), EML4-ALK inhibitor
    CAS: 1454846-35-5 EC Number: 813-704-5 PubChem CID: 71731823 Formula: C21H19FN6O2 Molecular Weight: 406.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: L409078
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    Technical Identifiers
    Synonyms
    (10R)-7-amino-12-fluoro-10,15,16,17-tetrahydro-2,10,16-trimethyl-15-oxo-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxad...
  8. Orantinib (SU6668), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    Wish List Compare
    Orantinib (SU6668), Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of kinase insert domain receptor;Inhibitor of platelet derived growth factor receptor beta
    CAS: 252916-29-3 PubChem CID: 5329099 Formula: C18H18N2O3 Molecular Weight: 310.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: O407925
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    Technical Identifiers
    Synonyms
    TSU-68 | (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
  9. no_selection
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    (2R)-2-[5-[6-amino-5-[(1R)-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol, Inhibitor of ALK receptor tyrosine kinase;Inhibitor of c-ros oncogene 1; receptor tyrosine kinase;Inhibitor of FER tyrosine kinase;Inhibitor of FES proto-oncogene; tyrosine kinase;Inhibitor of leukocyte receptor tyrosine kinase;Inhibitor of mitogen-activa
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: R609456
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    Technical Identifiers
    IUPAC Name
    (2R)-2-[5-[6-amino-5-[(1R)-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]propane-1,2-diol
    SMILES
    OC[C@](c1nc(c(s1)c1cnc(c(c1)O[C@@H](c1cc(F)ccc1n1nccn1)C)N)C)(O)C
    InChIKey
    DIXMBHMNEHPFCX-MCMMXHMISA-N
    InChI
    1S/C22H23FN6O3S/c1-12-19(33-21(28-12)22(3,31)11-30)14-8-18(20(24)25-10-14)32-13(2)16-9-15(23)4-5-17(16)29-26-6-7-27-29/h4-10,13,30-31H,11H2,1-3H3,(H2,show more
    Synonyms
    (2R)-2-[5-[6-amino-5-[(1R)-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]pyridin-3-yl]-4-methyl-1,3-thiazol-2-yl]propane-...
  10. no_selection
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    DS21360717, Inhibitor of FER tyrosine kinase
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: D609977
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    IUPAC Name
    7-{[(1R,2S)-2-aminocyclohexyl]amino}-5-[(3-methylphenyl)amino]-4-oxo-3H,4H-pyrido[3,4-d]pyridazine-8-carbonitrile
    SMILES
    N#Cc1c(N[C@@H]2CCCC[C@@H]2N)nc(c2c1cn[nH]c2=O)Nc1cccc(c1)C
    InChIKey
    VFVLUXBYMUKJIJ-DLBZAZTESA-N
    InChI
    1S/C21H23N7O/c1-12-5-4-6-13(9-12)25-20-18-15(11-24-28-21(18)29)14(10-22)19(27-20)26-17-8-3-2-7-16(17)23/h4-6,9,11,16-17H,2-3,7-8,23H2,1H3,(H,28,29)(H2show more
    Synonyms
    compound 21 [Taniguchi et al., 2019]
  12. TAK1/MAP4K2 inhibitor 1
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    TAK1/MAP4K2 inhibitor 1
    CAS: 1315330-11-0 PubChem CID: 71254032 Formula: C29H31F3N6O2 Molecular Weight: 552.59
    ≥98%
    Out of Stock Item #: T648184
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    Technical Identifiers
    IUPAC Name
    N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]benzamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F
    InChIKey
    RWNAOXLCVXJMGM-UHFFFAOYSA-N
    InChI
    1S/C29H31F3N6O2/c1-4-37-9-11-38(12-10-37)16-21-7-8-22(15-24(21)29(30,31)32)36-27(39)20-6-5-18(2)25(14-20)40-28-23-13-19(3)35-26(23)33-17-34-28/h5-8,13show more
    Synonyms
    AKOS016012030 | n-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-((6-methyl-7h-pyrrolo[2,3-...
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