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Tyrosine-protein kinase fgr (FGR)

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  1. KB SRC 4
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    KB SRC 4
    CAS: 1380088-03-8 Formula: C32H23ClN8 Molecular Weight: 555.03
    ≥98%(HPLC)
    In Stock Item #: K288228
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    IUPAC Name
    3-(4-chlorophenyl)-1-[3-[3-[(3-phenylphenyl)methyl]triazol-4-yl]phenyl]pyrazolo[3,4-d]pyrimidin-4-amine
    SMILES
    C1=CC=C(C=C1)C2=CC=CC(=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=NC=NC(=C6C(=N5)C7=CC=C(C=C7)Cl)N
    InChIKey
    UHIZYQVRKSWIFO-UHFFFAOYSA-N
    InChI
    1S/C32H23ClN8/c33-26-14-12-23(13-15-26)30-29-31(34)35-20-36-32(29)41(38-30)27-11-5-10-25(17-27)28-18-37-39-40(28)19-21-6-4-9-24(16-21)22-7-2-1-3-8-22/show more
    Synonyms
    1-[3-[1-([1,1'-Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-a...
  2. RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
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    RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
    CAS: 1242156-23-5 PubChem CID: 46908026 Formula: C35H35FN6O3 Molecular Weight: 606.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: R413708
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    IUPAC Name
    6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one
    SMILES
    CN1CCN(CC1)C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=CC=C4)N5C=CC6=CC(=CC(=C6C5=O)F)C7CC7)CO
    InChIKey
    ZTUJNJAKTLHBEX-UHFFFAOYSA-N
    InChI
    1S/C35H35FN6O3/c1-39-12-14-41(15-13-39)26-8-9-32(37-19-26)38-30-18-25(20-40(2)34(30)44)27-4-3-5-31(28(27)21-43)42-11-10-23-16-24(22-6-7-22)17-29(36)33show more
    Synonyms
    FT-0700142 | RN486 | RN-486 | 7G6 | 6-Cyclopropyl-8-Fluoranyl-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperaz...
  3. RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
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    RN486, Inhibitor of Bruton tyrosine kinase;Inhibitor of STE20 like kinase
    CAS: 1242156-23-5 PubChem CID: 46908026 Formula: C35H35FN6O3 Molecular Weight: 606.69
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: R421041
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    IUPAC Name
    6-cyclopropyl-8-fluoro-2-[2-(hydroxymethyl)-3-[1-methyl-5-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]-6-oxopyridin-3-yl]phenyl]isoquinolin-1-one
    SMILES
    CN1CCN(CC1)C2=CN=C(C=C2)NC3=CC(=CN(C3=O)C)C4=C(C(=CC=C4)N5C=CC6=CC(=CC(=C6C5=O)F)C7CC7)CO
    InChIKey
    ZTUJNJAKTLHBEX-UHFFFAOYSA-N
    InChI
    1S/C35H35FN6O3/c1-39-12-14-41(15-13-39)26-8-9-32(37-19-26)38-30-18-25(20-40(2)34(30)44)27-4-3-5-31(28(27)21-43)42-11-10-23-16-24(22-6-7-22)17-29(36)33show more
    Synonyms
    FT-0700142 | RN486 | RN-486 | 7G6 | 6-Cyclopropyl-8-Fluoranyl-2-[2-(Hydroxymethyl)-3-[1-Methyl-5-[[5-(4-Methylpiperaz...
  4. no_selection
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    N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of Bruton tyrosine kinase;Inhibitor of FGR proto-oncogene; Src family tyrosine kinase;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kin
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N609054
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    IUPAC Name
    N-[(1S)-1-(5-fluoropyridin-2-yl)ethyl]-3-(3-propan-2-yloxy-1H-pyrazol-5-yl)imidazo[4,5-b]pyridin-5-amine
    SMILES
    CC(Oc1[nH]nc(c1)n1cnc2c1nc(cc2)N[C@H](c1ccc(cn1)F)C)C
    InChIKey
    FZBVNCFBCNXULH-LBPRGKRZSA-N
    InChI
    1S/C19H20FN7O/c1-11(2)28-18-8-17(25-26-18)27-10-22-15-6-7-16(24-19(15)27)23-12(3)14-5-4-13(20)9-21-14/h4-12H,1-3H3,(H,23,24)(H,25,26)/t12-/m0/s1
    Synonyms
    compound 2c
  5. no_selection
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    eCF506, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of FGR proto-oncogene; Src family tyrosine kinase;Inhibitor of FYN proto-oncogene; Src family tyrosine kinase;Inhibitor o
    CAS: 1914078-41-3 PubChem CID: 121231408 Formula: C26H38N8O3 Molecular Weight: 510.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: E610058
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    IUPAC Name
    tert-butyl N-[4-[4-amino-1-[2-[4-(dimethylamino)piperidin-1-yl]ethyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl]carbamate
    SMILES
    CC(C)(C)OC(=O)NC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)CCN4CCC(CC4)N(C)C)OC
    InChIKey
    GMPQGWXPDRNCBL-UHFFFAOYSA-N
    InChI
    1S/C26H38N8O3/c1-26(2,3)37-25(35)30-19-8-7-17(15-20(19)36-6)22-21-23(27)28-16-29-24(21)34(31-22)14-13-33-11-9-18(10-12-33)32(4)5/h7-8,15-16,18H,9-14H2show more
    Synonyms
    derivative 11a
  6. no_selection
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    N-(2-chloro-6-methylphenyl)-2-[(2,6-dimethylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide, Inhibitor of BLK proto-oncogene; Src family tyrosine kinase;Inhibitor of FGR proto-oncogene; Src family tyrosine kinase;Inhibitor of FYN proto-oncogene; Src family tyrosine kinase;Inhibitor of HCK proto-oncogene; Src family tyrosine kinase;Inhibitor of Ja
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N609072
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    Technical Identifiers
    IUPAC Name
    N-(2-chloro-6-methylphenyl)-2-[(2,6-dimethylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide
    SMILES
    Cc1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(n1)C
    InChIKey
    WFRLFWGASBLYTC-UHFFFAOYSA-N
    InChI
    1S/C17H16ClN5OS/c1-9-5-4-6-12(18)15(9)23-16(24)13-8-19-17(25-13)22-14-7-10(2)20-11(3)21-14/h4-8H,1-3H3,(H,23,24)(H,19,20,21,22)
    Synonyms
    compound 2 [PMID: 15546730] | SCHEMBL774220 | Q27076526 | N-(2-Chloro-6-methylphenyl)-2-((2,6-dimethylpyrimidin-4-yl)...
  9. N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
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    N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
    CAS: 861874-34-2 PubChem CID: 11441375 Formula: C25H22N2O4 Molecular Weight: 414.5
    Out of Stock Item #: N669143
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    IUPAC Name
    N-cyclopropyl-6-(6,7-dimethoxyquinolin-4-yl)oxynaphthalene-1-carboxamide
    SMILES
    COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC4=C(C=C3)C(=CC=C4)C(=O)NC5CC5
    InChIKey
    ZATGFXTWDKIEKC-UHFFFAOYSA-N
    InChI
    1S/C25H22N2O4/c1-29-23-13-20-21(14-24(23)30-2)26-11-10-22(20)31-17-8-9-18-15(12-17)4-3-5-19(18)25(28)27-16-6-7-16/h3-5,8-14,16H,6-7H2,1-2H3,(H,27,28)
    Synonyms
    861874-34-2 | N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide | VEGFR-IN-V | 1-Naphthalene...
  10. 3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol
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    3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol
    CAS: 1228102-01-9 Formula: C24H23N3O2S Molecular Weight: 417.5
    Out of Stock Item #: M1259919
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    IUPAC Name
    3-[[2-[3-(morpholin-4-ylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenol
    SMILES
    C1COCCN1CC2=CC(=CC=C2)C3=CC4=NC=CC(=C4S3)NC5=CC(=CC=C5)O
    InChIKey
    ZCWXCBKGPJOAFQ-UHFFFAOYSA-N
    InChI
    1S/C24H23N3O2S/c28-20-6-2-5-19(14-20)26-21-7-8-25-22-15-23(30-24(21)22)18-4-1-3-17(13-18)16-27-9-11-29-12-10-27/h1-8,13-15,28H,9-12,16H2,(H,25,26)
  12. KB SRC 4
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    KB SRC 4
    CAS: 1380088-03-8 Formula: C32H23ClN8 Molecular Weight: 555.03
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Out of Stock Item #: K1494116
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