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Salt-inducible Kinase (SIK)

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  1. ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: A421945
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  2. ARN-3236 - Moligand™, ≥98%, CAS No. 1613710-01-2 by
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    ARN-3236, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1613710-01-2 Formula: C19H16N2O2S Molecular Weight: 336.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A414050
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    Technical Identifiers
    IUPAC Name
    3-(2,4-dimethoxyphenyl)-4-thiophen-3-yl-1H-pyrrolo[2,3-b]pyridine
    SMILES
    COC1=CC(=C(C=C1)C2=CNC3=NC=CC(=C23)C4=CSC=C4)OC
    InChIKey
    WEHOIIGXTMKVRG-UHFFFAOYSA-N
    InChI
    1S/C19H16N2O2S/c1-22-13-3-4-15(17(9-13)23-2)16-10-21-19-18(16)14(5-7-20-19)12-6-8-24-11-12/h3-11H,1-2H3,(H,20,21)
    Synonyms
    1H-​Pyrrolo[2,​3-​b]​pyridine,3-​(2,​4-​dimethoxyphenyl)​-​4-​(3-​thienyl)​-
  3. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: H421682
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    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  4. HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
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    HG-9-91-01, Inhibitor of salt inducible kinase 1;Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 1456858-58-4 Formula: C32H37N7O3 Molecular Weight: 567.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: H413999
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea
    SMILES
    CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
    InChIKey
    UYUHRKLITDJEHB-UHFFFAOYSA-N
    InChI
    1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-show more
    Synonyms
    BCP25041 | DTXSID401025699 | SCHEMBL15271960 | SIK inhibitor 1 | HG-9-91-01 (1) | MS-30272 | 1-(2,4-Dimethoxyphenyl)-...
  5. YKL 06-061
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    YKL 06-061
    CAS: 2172617-15-9 PubChem CID: 132992144 Formula: C30H37N7O2 Molecular Weight: 527.66
    ≥99%
    In Stock Item #: Y412151
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    Technical Identifiers
    IUPAC Name
    1-cyclobutyl-3-(2,6-dimethylphenyl)-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)C)N2CC3=CN=C(N=C3N(C2=O)C4CCC4)NC5=C(C=C(C=C5)N6CCN(CC6)C)OC
    InChIKey
    GVBAXIVNAHMIGH-UHFFFAOYSA-N
    InChI
    1S/C30H37N7O2/c1-20-7-5-8-21(2)27(20)36-19-22-18-31-29(33-28(22)37(30(36)38)23-9-6-10-23)32-25-12-11-24(17-26(25)39-4)35-15-13-34(3)14-16-35/h5,7-8,11show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,1-​cyclobutyl-​3-​(2,​6-​dimethylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-�...
  6. YKL 06-061
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    YKL 06-061
    CAS: 2172617-15-9 PubChem CID: 132992144 Formula: C30H37N7O2 Molecular Weight: 527.66
    10mM in DMSO
    In Stock Item #: Y422614
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    Technical Identifiers
    IUPAC Name
    1-cyclobutyl-3-(2,6-dimethylphenyl)-7-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)C)N2CC3=CN=C(N=C3N(C2=O)C4CCC4)NC5=C(C=C(C=C5)N6CCN(CC6)C)OC
    InChIKey
    GVBAXIVNAHMIGH-UHFFFAOYSA-N
    InChI
    1S/C30H37N7O2/c1-20-7-5-8-21(2)27(20)36-19-22-18-31-29(33-28(22)37(30(36)38)23-9-6-10-23)32-25-12-11-24(17-26(25)39-4)35-15-13-34(3)14-16-35/h5,7-8,11show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,1-​cyclobutyl-​3-​(2,​6-​dimethylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-�...
  7. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    10mM in DMSO
    In Stock Item #: Y422363
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    Technical Identifiers
    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    Pyrimido[4,​5-​d]​pyrimidin-​2(1H)​-​one,3-​(2-​chloro-​6-​methylphenyl)​-​3,​4-​dihydro-​7-​[[2-​methoxy-​4-​(1-​met...
  8. YKL-05-099
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    YKL-05-099
    CAS: 1936529-65-5 PubChem CID: 121596782 Formula: C32H34ClN7O3 Molecular Weight: 600.11
    ≥98%
    In Stock Item #: Y414441
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    Technical Identifiers
    IUPAC Name
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5-d]pyrimidin-2-one
    SMILES
    CC1=C(C(=CC=C1)Cl)N2CC3=CN=C(N=C3N(C2=O)C4=NC=C(C=C4)OC)NC5=C(C=C(C=C5)C6CCN(CC6)C)OC
    InChIKey
    VQINULODWGEVBB-UHFFFAOYSA-N
    InChI
    1S/C32H34ClN7O3/c1-20-6-5-7-25(33)29(20)39-19-23-17-35-31(37-30(23)40(32(39)41)28-11-9-24(42-3)18-34-28)36-26-10-8-22(16-27(26)43-4)21-12-14-38(2)15-1show more
    Synonyms
    3-(2-chloro-6-methylphenyl)-7-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]-1-(5-methoxypyridin-2-yl)-4H-pyrimido[4,5...
  9. no_selection
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    GLPG3970, Inhibitor of salt inducible kinase 2;Inhibitor of SIK family kinase 3
    CAS: 2403733-82-2 PubChem CID: 146273261
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610582
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    Technical Identifiers
    IUPAC Name
    8-methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one
    SMILES
    COc1cc(cc2c1C(=O)N(CC2)CC(F)(F)F)c1cnc2n1ccc(c2)OCCN1CCOCC1
    InChIKey
    XASOHFCUIQARJT-UHFFFAOYSA-N
    InChI
    1S/C25H27F3N4O4/c1-34-21-13-18(12-17-2-4-31(16-25(26,27)28)24(33)23(17)21)20-15-29-22-14-19(3-5-32(20)22)36-11-8-30-6-9-35-10-7-30/h3,5,12-15H,2,4,6-1show more
    Synonyms
    GTPL12157 | XASOHFCUIQARJT-UHFFFAOYSA-N | 8-Methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2...
  11. WH-4-025
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    WH-4-025
    CAS: 1876463-35-2 PubChem CID: 73707529 Formula: C39H38F3N7O5 Molecular Weight: 741.76
    ≥98%
    Out of Stock Item #: W648282
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    Technical Identifiers
    IUPAC Name
    [2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl] N-(2,4-dimethoxyphenyl)-N-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamate
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC(=O)N(C3=C(C=C(C=C3)OC)OC)C4=NC(=NC=C4)NC5=CC=C(C=C5)N6CCN(CC6)C
    InChIKey
    MWWDOHSKUDECFQ-UHFFFAOYSA-N
    InChI
    1S/C39H38F3N7O5/c1-25-8-9-26(36(50)44-29-7-5-6-27(23-29)39(40,41)42)22-33(25)54-38(51)49(32-15-14-31(52-3)24-34(32)53-4)35-16-17-43-37(46-35)45-28-10-show more
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