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Na+/H+ Exchanger (NHE)

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  1. Zoniporide dihydrochloride
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    Zoniporide dihydrochloride
    CAS: 241799-10-0 PubChem CID: 22267855 Formula: C17H16N6O.2HCl Molecular Weight: 393.27
    ≥99%(HPLC)
    Out of Stock Item #: Z287415
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    Technical Identifiers
    IUPAC Name
    5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide;dihydrochloride
    SMILES
    C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)N=C(N)N.Cl.Cl
    InChIKey
    ARZNPJAGKWHEHT-UHFFFAOYSA-N
    InChI
    1S/C17H16N6O.2ClH/c18-17(19)22-16(24)12-9-21-23(15(12)10-6-7-10)14-5-1-4-13-11(14)3-2-8-20-13;;/h1-5,8-10H,6-7H2,(H4,18,19,22,24);2*1H
    Synonyms
    CP 597396 | [1-(Quinolin-5-yl)-5-cyclopropyl-1H-pyrazole-4-carbonyl]guanidine dihydrochloride
  2. BI-9627 hydrochloride
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    BI-9627 hydrochloride
    CAS: 1422252-46-7 PubChem CID: 121513866 Formula: C16H19F3N4O2(free) Molecular Weight: 356.34(free)
    ≥95%
    In Stock Item #: B286959
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    IUPAC Name
    4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide;hydrochloride
    SMILES
    CC(=O)N1CCC(CC1)C2=C(C=C(C=C2)C(=O)N=C(N)N)C(F)(F)F.Cl
    InChIKey
    SLSZLEROFKLICF-UHFFFAOYSA-N
    InChI
    1S/C16H19F3N4O2.ClH/c1-9(24)23-6-4-10(5-7-23)12-3-2-11(14(25)22-15(20)21)8-13(12)16(17,18)19;/h2-3,8,10H,4-7H2,1H3,(H4,20,21,22,25);1H
    Synonyms
    BIX Hydrochloride | BIX HCl | Benzamide, 4-(1-acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)-, hydroc...
  3. Dimethylamiloride hydrochloride - ≥97% CAS No(2235-97-4) by Aladdin Scientific
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    Dimethylamiloride hydrochloride
    CAS: 2235-97-4 Formula: C8H12ClN7O.HCl Molecular Weight: 294.14
    ≥97%
    In Stock Item #: D275816
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    IUPAC Name
    3-amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide;hydrochloride
    SMILES
    CN(C)C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N.Cl
    InChIKey
    IIUPTHVVXMBJMQ-UHFFFAOYSA-N
    InChI
    1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H
    Synonyms
    DMA.HCl | UNII-52W30K1Q9Q | 3-Amino-5-(N,N-dimethylamino)-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide | 5-(N,N-D...
  4. EIPA, Allosteric modulator of α 2A-adrenoceptor;Channel blocker of ASIC1;Channel blocker of TRPP2
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    EIPA, Allosteric modulator of α 2A-adrenoceptor;Channel blocker of ASIC1;Channel blocker of TRPP2
    CAS: 1154-25-2 EC Number: 634-217-2 Formula: C11H18ClN7O Molecular Weight: 299.76
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: N132356
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    IUPAC Name
    3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide
    SMILES
    CCN(C1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N)C(C)C
    InChIKey
    QDERNBXNXJCIQK-UHFFFAOYSA-N
    InChI
    1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
    Synonyms
    5-(Ethylisopropyl)amiloride | Ethylisopropyl amiloride | EU-0100045 | HY-101840 | SMR000326875 | Tox21_500045 | 3-Ami...
  5. Monensin sodium salt - ≥90%(HPLC) CAS No(22373-78-0) by Aladdin Scientific
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    Monensin sodium salt
    CAS: 22373-78-0 EC Number: 244-941-7 Formula: C36H61NaO11 Molecular Weight: 692.85
    Solid ≥90%(HPLC)
    In Stock Item #: M163019
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    Technical Identifiers
    IUPAC Name
    sodium;(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxoshow more
    SMILES
    CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+]
    InChIKey
    XOIQMTLWECTKJL-FBZUZRIGSA-M
    InChI
    1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)show more
    Synonyms
    AKOS025147337 | CAS-22373-78-0 | DTXSID2045573 | HMS2097E18 | 4-[2-[5-Ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dim...
  6. Monensin sodium salt - ≥97% CAS No(22373-78-0) by Aladdin Scientific
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    Monensin sodium salt
    CAS: 22373-78-0 EC Number: 244-941-7 Formula: C36H61NaO11 Molecular Weight: 692.85
    Solid ≥97%
    In Stock Item #: M118287
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    Technical Identifiers
    IUPAC Name
    sodium;(2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2R,5S)-5-ethyl-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxoshow more
    SMILES
    CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)[O-])OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C.[Na+]
    InChIKey
    XOIQMTLWECTKJL-FBZUZRIGSA-M
    InChI
    1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)show more
    Synonyms
    AKOS025147337 | CAS-22373-78-0 | DTXSID2045573 | HMS2097E18 | 4-[2-[5-Ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dim...
  7. Cariporide
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    Cariporide
    CAS: 159138-80-4 Formula: C12H17N3O3S Molecular Weight: 283.35
    ≥98%(HPLC)
    In Stock Item #: C286810
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    Technical Identifiers
    IUPAC Name
    N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide
    SMILES
    CC(C)C1=C(C=C(C=C1)C(=O)N=C(N)N)S(=O)(=O)C
    InChIKey
    IWXNYAIICFKCTM-UHFFFAOYSA-N
    InChI
    1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)
    Synonyms
    N-carbamimidoyl-3-methanesulfonyl-4-(propan-2-yl)benzamide | AC-14535 | 3-methylsulfonyl-4-i-propylbenzoylguanidine |...
  8. Cariporide
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    Cariporide
    CAS: 159138-80-4 Formula: C12H17N3O3S Molecular Weight: 283.35
    10mM in DMSO
    In Stock Item #: C421903
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    Technical Identifiers
    IUPAC Name
    N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide
    SMILES
    CC(C)C1=C(C=C(C=C1)C(=O)N=C(N)N)S(=O)(=O)C
    InChIKey
    IWXNYAIICFKCTM-UHFFFAOYSA-N
    InChI
    1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)
    Synonyms
    N-carbamimidoyl-3-methanesulfonyl-4-(propan-2-yl)benzamide | AC-14535 | 3-methylsulfonyl-4-i-propylbenzoylguanidine |...
  9. KR-32568
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    KR-32568
    CAS: 852146-73-7 Formula: C13H12FN3O2 Molecular Weight: 261.25
    ≥98%
    In Stock Item #: K336935
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    Technical Identifiers
    IUPAC Name
    N-(diaminomethylidene)-5-(5-fluoro-2-methylphenyl)furan-2-carboxamide
    SMILES
    CC1=C(C=C(C=C1)F)C2=CC=C(O2)C(=O)N=C(N)N
    InChIKey
    DTLDHYBZLVASJQ-UHFFFAOYSA-N
    InChI
    1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18)
    Synonyms
    N-(Aminoiminomethyl)-5-(5-fluoro-2-methylphenyl)-2-furancarboxamide
  10. Rimeporide - , used for , CAS No. 187870-78-6, by Aladdin Scientific
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    Rimeporide
    CAS: 187870-78-6 Formula: C11H15N3O5S2 Molecular Weight: 333.38
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: R412316
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    Technical Identifiers
    IUPAC Name
    N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide
    SMILES
    CC1=CC(=C(C=C1C(=O)N=C(N)N)S(=O)(=O)C)S(=O)(=O)C
    InChIKey
    GROMEQPXDKRRIE-UHFFFAOYSA-N
    InChI
    1S/C11H15N3O5S2/c1-6-4-8(20(2,16)17)9(21(3,18)19)5-7(6)10(15)14-11(12)13/h4-5H,1-3H3,(H4,12,13,14,15)
    Synonyms
    N-diaminomethylene-2-methyl-4,5-di(methylsulfonyl)benzamide | D80911 | EMD-87580 pound>>EMD 87580 pound>>EMD87580 | A...
  11. no_selection
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    Tenapanor, Inhibitor of Sodium/hydrogen exchanger 3
    CAS: 1234423-95-0 Formula: C50H66Cl4N8O10S2 Molecular Weight: 1145.05
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: T614379
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    Technical Identifiers
    IUPAC Name
    1-[2-[2-[2-[[3-[(4S)-6,8-dichloro-2-methyl-3,4-dihydro-1H-isoquinolin-4-yl]phenyl]sulfonylamino]ethoxy]ethoxy]ethyl]-3-[4-[2-[2-[2-[[3-[(4S)-6,8-dichlshow more
    SMILES
    CN1CC(C2=C(C1)C(=CC(=C2)Cl)Cl)C3=CC(=CC=C3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)C4=CC=CC(=C4)C5CN(CC6=C5C=C(C=C6Cl)Cl)C
    InChIKey
    DNHPDWGIXIMXSA-CXNSMIOJSA-N
    InChI
    1S/C50H66Cl4N8O10S2/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)show more
    Synonyms
    tenapanorum | WYD79216A6 | AC-36104 | US10272079, Compound 002 | HY-15991 | (S)-3-hydroxy-2-methyl-Propanoate | Tenap...
  12. Zoniporide
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    Zoniporide
    CAS: 241800-98-6 EC Number: 695-536-0 PubChem CID: 6433110 Formula: C17H16N6O Molecular Weight: 320.35
    Solid ≥97%
    In Stock Item #: N633068
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    Technical Identifiers
    IUPAC Name
    5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide
    SMILES
    C1CC1C2=C(C=NN2C3=CC=CC4=C3C=CC=N4)C(=O)N=C(N)N
    InChIKey
    GDXBRVCQGGKXJY-UHFFFAOYSA-N
    InChI
    1S/C17H16N6O/c18-17(19)22-16(24)12-9-21-23(15(12)10-6-7-10)14-5-1-4-13-11(14)3-2-8-20-13/h1-5,8-10H,6-7H2,(H4,18,19,22,24)
    Synonyms
    Zoniporide | 5-cyclopropyl-N-(diaminomethylidene)-1-quinolin-5-ylpyrazole-4-carboxamide | 8841R2UJPG | N-carbamimidoy...
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