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TRP Channel

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  1. GSK-1016790A, Activator of TRPV4
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    GSK-1016790A, Activator of TRPV4
    CAS: 942206-85-1 Formula: C28H32Cl2N4O6S2 Molecular Weight: 655.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G275374
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    Technical Identifiers
    IUPAC Name
    N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
    SMILES
    CC(C)CC(C(=O)N1CCN(CC1)C(=O)C(CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3
    InChIKey
    IVYQPSHHYIAUFO-VXKWHMMOSA-N
    InChI
    1S/C28H32Cl2N4O6S2/c1-17(2)13-21(31-26(36)24-14-18-5-3-4-6-23(18)41-24)27(37)33-9-11-34(12-10-33)28(38)22(16-35)32-42(39,40)25-8-7-19(29)15-20(25)30/hshow more
    Synonyms
    GSK101 | HY-19608 | GSK 1016790A | N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]pipera...
  2. Linopirdine dihydrochloride
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    Linopirdine dihydrochloride
    CAS: 113168-57-3 PubChem CID: 14209557 Formula: C26H21N3O.2HCl Molecular Weight: 464.39
    ≥98%
    Out of Stock Item #: L274931
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    IUPAC Name
    1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;dihydrochloride
    SMILES
    C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
    InChIKey
    ZEVVHCGTTNRYOY-UHFFFAOYSA-N
    InChI
    1S/C26H21N3O.2ClH/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22;;/h1-17H,18-19H2;2*1H
    Synonyms
    1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-onedihydrochloride
  3. GSK 2193874, Channel blocker of TRPV4
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    GSK 2193874, Channel blocker of TRPV4
    CAS: 1336960-13-4 EC Number: 808-437-6 Formula: C37H38BrF3N4O Molecular Weight: 691.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G287297
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    IUPAC Name
    7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
    SMILES
    C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7
    InChIKey
    UIVOZBSCHXCGPS-UHFFFAOYSA-N
    InChI
    1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36show more
    Synonyms
    GSK2193874 | GSK-2193874 | GTPL6465 | NCGC00370767-01 | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopr...
  4. GSK 1702934A, Activator of TRPC3;Activator of TRPC6
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    GSK 1702934A, Activator of TRPC3;Activator of TRPC6
    CAS: 924377-85-5 Formula: C22H25N3O2S Molecular Weight: 395.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Out of Stock Item #: G288131
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    IUPAC Name
    3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one
    SMILES
    C1CCC2=C(CC1)SC(=C2)C(=O)N3CCC(CC3)N4C5=CC=CC=C5NC4=O
    InChIKey
    AXWRAIIIBRLXBP-UHFFFAOYSA-N
    InChI
    1S/C22H25N3O2S/c26-21(20-14-15-6-2-1-3-9-19(15)28-20)24-12-10-16(11-13-24)25-18-8-5-4-7-17(18)23-22(25)27/h4-5,7-8,14,16H,1-3,6,9-13H2,(H,23,27)
    Synonyms
    GSK1702934A | GSK-1702934A | 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl...
  5. NADA (N-Arachidonyldopamine), Channel blocker of TRPM8;Channel blocker of TRPV1
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    NADA (N-Arachidonyldopamine), Channel blocker of TRPM8;Channel blocker of TRPV1
    CAS: 199875-69-9 PubChem CID: 5282105 Formula: C28H41NO3 Molecular Weight: 439.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N275117
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    IUPAC Name
    (5Z,8Z,11Z,14Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]icosa-5,8,11,14-tetraenamide
    SMILES
    CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCC1=CC(=C(C=C1)O)O
    InChIKey
    MVVPIAAVGAWJNQ-DOFZRALJSA-N
    InChI
    1S/C28H41NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(32)29-23-22-25-20-21-26(30)27(31)24-25/h6-7,9-10,12-13,15-16,20-21,24,30-31H,2-5,8,11show more
    Synonyms
    5,8,11,14-EICOSATETRAENAMIDE, N-(2-(3,4-DIHYDROXYPHENYL)ETHYL)-, (5Z,8Z,11Z,14Z)- | SR-01000946639 | Q3869319 | AA-DA...
  6. PF 05105679, Channel blocker of TRPM8
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    PF 05105679, Channel blocker of TRPM8
    CAS: 1398583-31-7 EC Number: 809-223-5 PubChem CID: 60195662 Formula: C26H21FN2O3 Molecular Weight: 428.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: P287705
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    IUPAC Name
    3-[[[(1R)-1-(4-fluorophenyl)ethyl]-(quinoline-3-carbonyl)amino]methyl]benzoic acid
    SMILES
    CC(C1=CC=C(C=C1)F)N(CC2=CC(=CC=C2)C(=O)O)C(=O)C3=CC4=CC=CC=C4N=C3
    InChIKey
    BXNMZRPTQFVRFA-QGZVFWFLSA-N
    InChI
    1S/C26H21FN2O3/c1-17(19-9-11-23(27)12-10-19)29(16-18-5-4-7-21(13-18)26(31)32)25(30)22-14-20-6-2-3-8-24(20)28-15-22/h2-15,17H,16H2,1H3,(H,31,32)/t17-/mshow more
    Synonyms
    PF 05105679 | (R)-3-((N-(1-(4-fluorophenyl)ethyl)quinoline-3-carboxamido)methyl)benzoic acid | SCHEMBL12487950 | PF05...
  7. 1-Stearoyl-2-arachidonoyl-sn-glycerol, Activator of TRPC6
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    1-Stearoyl-2-arachidonoyl-sn-glycerol, Activator of TRPC6
    CAS: 65914-84-3 PubChem CID: 6438587 Formula: C41H72O5 Molecular Weight: 645.01
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% 25mg/ml in methyl acetate
    Out of Stock Item #: S347974
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    IUPAC Name
    [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
    SMILES
    CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
    InChIKey
    NSXLMTYRMFVYNT-IUJDHQGTSA-N
    InChI
    1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h11,13,1show more
    Synonyms
    DG(18:0/20:4(omega-6)/0:0) | DG(18:0/20:4omega6) | (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icos...
  8. SAR7334 hydrochloride
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    SAR7334 hydrochloride
    CAS: 1333207-63-8 PubChem CID: 78357800 Formula: C21H24Cl3N3O Molecular Weight: 440.79
    ≥98%(HPLC)
    Out of Stock Item #: S286732
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    IUPAC Name
    4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile;dihydrochloride
    SMILES
    C1CC(CN(C1)C2CC3=CC=CC=C3C2OC4=C(C=C(C=C4)C#N)Cl)N.Cl.Cl
    InChIKey
    LFMYIKNZNTZSJX-IQJQELQDSA-N
    InChI
    1S/C21H22ClN3O.2ClH/c22-18-10-14(12-23)7-8-20(18)26-21-17-6-2-1-4-15(17)11-19(21)25-9-3-5-16(24)13-25;;/h1-2,4,6-8,10,16,19,21H,3,5,9,11,13,24H2;2*1H/show more
    Synonyms
    4-[[(1R,2R)-2-[(3R)-3-Amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile dihydrochloride
  9. Methyl 3,5-dimethoxy-4-hydroxybenzoate
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    Methyl 3,5-dimethoxy-4-hydroxybenzoate
    CAS: 884-35-5 EC Number: 429-050-5 Formula: C10H12O5 Molecular Weight: 212.2
    ≥98%
    In Stock Item #: M334230
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    Technical Identifiers
    IUPAC Name
    methyl 4-hydroxy-3,5-dimethoxybenzoate
    SMILES
    COC1=CC(=CC(=C1O)OC)C(=O)OC
    InChIKey
    ZMXJAEGJWHJMGX-UHFFFAOYSA-N
    InChI
    1S/C10H12O5/c1-13-7-4-6(10(12)15-3)5-8(14-2)9(7)11/h4-5,11H,1-3H3
    Synonyms
    M2806 | MFCD00017199 | Syringic acid monomethyl ester | UNII-W5A196MP8A | Fenaluz Turquoise G | SBB016976 | SY032894 ...
  10. cis-Capsaicin, Vanilloid receptor agonist
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    cis-Capsaicin, Vanilloid receptor agonist
    CAS: 25775-90-0 EC Number: 636-760-0 Formula: C18H27NO3 Molecular Weight: 305.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: C346860
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    IUPAC Name
    (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
    SMILES
    CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
    InChIKey
    YKPUWZUDDOIDPM-VURMDHGXSA-N
    InChI
    1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6-
    Synonyms
    AC-31789 | HMS2051O07 | CHEBI:135952 | MLS000758306 | ZUCAPSAICIN [INN] | NCGC00017337-01 | (6Z)-N-[(4-hydroxy-3-meth...
  11. SB 452533, Channel blocker of TRPV1
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    SB 452533, Channel blocker of TRPV1
    CAS: 459429-39-1 PubChem CID: 9842609 Formula: C18H22BrN3O Molecular Weight: 376.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: S288655
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    IUPAC Name
    1-(2-bromophenyl)-3-[2-(N-ethyl-3-methylanilino)ethyl]urea
    SMILES
    CCN(CCNC(=O)NC1=CC=CC=C1Br)C2=CC=CC(=C2)C
    InChIKey
    IFJYEGJUQIBBQV-UHFFFAOYSA-N
    InChI
    1S/C18H22BrN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23)
    Synonyms
    n-(2-bromophenyl)-n'-[2-[ethyl(3-methylphenyl)amino]ethyl]urea | N-(2-Bromophenyl)-N'-[2-[ethyl(3-methylphenyl)amino]...
  12. SB-366791, Channel blocker of TRPV1
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    SB-366791, Channel blocker of TRPV1
    CAS: 472981-92-3 PubChem CID: 667594 Formula: C16H14ClNO2 Molecular Weight: 287.74
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S275140
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    IUPAC Name
    (E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide
    SMILES
    COC1=CC=CC(=C1)NC(=O)C=CC2=CC=C(C=C2)Cl
    InChIKey
    RYAMDQKWNKKFHD-JXMROGBWSA-N
    InChI
    1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
    Synonyms
    SR-01000597592-1 | 4'-CHLORO-3-METHOXYCINNAMANILIDE | 4-CHLORO-3-METHOXYCINNAMANILIDE | UNII-E8EY4M2N4H | SR-01000597...
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