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Syk

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  1. Syk Inhibitor IV, BAY 61-3606 HCl - ≥97%, used for , CAS No. 732983-37-8, by Aladdin Scientific
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    BAY 61-3606, Inhibitor of component of inhibitor of nuclear factor kappa B kinase complex;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of spleen associated tyrosine kinase
    CAS: 732983-37-8 Formula: C20H18N6O3 Molecular Weight: 390.40
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: S340911
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC
    InChIKey
    JWQOJVOKBAAAAR-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19/h3-11H,1-2H3,(H2,21,27)(H,23,24,25)
    Synonyms
    Kinome_3125 | BAY-61-360 | UNII-61G8S0H9KX | BAY 61-3606 free base | CCG-102604 | AT32059 | BAY-61-3606 free base | D...
  2. Syk Inhibitor II
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    Syk Inhibitor II
    CAS: 227449-73-2 PubChem CID: 16760670 Formula: C14H15F3N6O・2HCl・2H2O Molecular Weight: 449.26
    Out of Stock Item #: S341312
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    Technical Identifiers
    IUPAC Name
    2-(2-aminoethylamino)-4-[3-(trifluoromethyl)anilino]pyrimidine-5-carboxamide;dihydrate;dihydrochloride
    SMILES
    C1=CC(=CC(=C1)NC2=NC(=NC=C2C(=O)N)NCCN)C(F)(F)F.O.O.Cl.Cl
    InChIKey
    LCACSMNPIITJGG-UHFFFAOYSA-N
    InChI
    1S/C14H15F3N6O.2ClH.2H2O/c15-14(16,17)8-2-1-3-9(6-8)22-12-10(11(19)24)7-21-13(23-12)20-5-4-18;;;;/h1-3,6-7H,4-5,18H2,(H2,19,24)(H2,20,21,22,23);2*1H;2show more
    Synonyms
    HY-112390B | Syk Inhibitor II (dihydrochloride dihydrate) | J-014840 | DTXSID70587914 | CCG-206793 | 2-(2-aminoethyla...
  3. Fostamatinib Disodium Hexahydrate, Tyrosine-protein kinase SYK inhibitor
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    Fostamatinib Disodium Hexahydrate, Tyrosine-protein kinase SYK inhibitor
    CAS: 914295-16-2 EC Number: 682-713-2 Formula: C23H36FN6Na2O15P Molecular Weight: 732.51
    ≥98%
    In Stock Item #: F336802
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    Technical Identifiers
    IUPAC Name
    disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate;hexahydrate
    SMILES
    CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.O.O.O.O.O.O.[Na+].[Na+]
    InChIKey
    ZQGJCHHKJNSPMS-UHFFFAOYSA-L
    InChI
    1S/C23H26FN6O9P.2Na.6H2O/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;show more
    Synonyms
    Fostamatinib disodium | Fostamatinib disodium [USAN] | Fostamatinib disodium hexahydrate | R-935788 | Tamatinib fosdi...
  4. R406 (free base), Tyrosine-protein kinase SYK inhibitor
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    R406 (free base), Tyrosine-protein kinase SYK inhibitor
    CAS: 841290-80-0 EC Number: 617-533-5 PubChem CID: 11213558 Formula: C22H23FN6O5 Molecular Weight: 470.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: R129910
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    Technical Identifiers
    IUPAC Name
    6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
    SMILES
    CC1(C(=O)NC2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)C
    InChIKey
    NHHQJBCNYHBUSI-UHFFFAOYSA-N
    InChI
    1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,show more
    Synonyms
    HY-11108 | 2H-PYRIDO[3,2-B]-1,4-OXAZIN-3(4H)-ONE,6-[[5-FLUORO-2-[(3,4,5-TRIMETHOXPHENYL)AMINO]-4-PYRIMIDINYL]AMINO]-2...
  5. R788 (Fostamatinib) Disodium
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    R788 (Fostamatinib) Disodium
    CAS: 1025687-58-4 PubChem CID: 25008120 Formula: C23H24FN6O9P·2Na Molecular Weight: 624.42
    ≥98%
    In Stock Item #: R129913
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    Technical Identifiers
    IUPAC Name
    disodium;[6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl phosphate
    SMILES
    CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.[Na+].[Na+]
    InChIKey
    HSYBQXDGYCYSGA-UHFFFAOYSA-L
    InChI
    1S/C23H26FN6O9P.2Na/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;/h6-1show more
    Synonyms
    CCG-270264 | R788 disodium (Fostamatinib) | 1025687-58-4 | FosD | R788(Fostamatinib disodium) | 2H-Pyrido(3,2-b)-1,4-...
  6. PRT062607 (P505-15, BIIB057) HCl
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    PRT062607 (P505-15, BIIB057) HCl
    CAS: 1370261-97-4 PubChem CID: 56948527 Formula: C19H23N9O·HCl Molecular Weight: 429.91
    ≥98%
    In Stock Item #: P129908
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    Technical Identifiers
    IUPAC Name
    2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide;hydrochloride
    SMILES
    C1CCC(C(C1)N)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)N4N=CC=N4)C(=O)N.Cl
    InChIKey
    RMNLLPXCNDZJMJ-IDVLALEDSA-N
    InChI
    1S/C19H23N9O.ClH/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28;/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(show more
    Synonyms
    PRT062607 Hydrochloride | 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5...
  7. Bay 61-3606 hydrochloride
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    Bay 61-3606 hydrochloride
    CAS: 732983-37-8 Formula: C20H18N6O3 Molecular Weight: 390.40
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: B275245
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC
    InChIKey
    JWQOJVOKBAAAAR-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19/h3-11H,1-2H3,(H2,21,27)(H,23,24,25)
    Synonyms
    2-[[7-(3,4-Dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamidehydrochloride
  8. ER 27319 maleate - ≥99% CAS No(1204480-26-1) by Aladdin Scientific
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    ER 27319 maleate
    CAS: 1204480-26-1 Formula: C18H20N2O•C4H4O4 Molecular Weight: 396.44
    ≥99%
    In Stock Item #: E288610
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    IUPAC Name
    10-(3-aminopropyl)-3,4-dimethylacridin-9-one;(Z)-but-2-enedioic acid
    SMILES
    CC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3N2CCCN)C.C(=CC(=O)O)C(=O)O
    InChIKey
    WVUQPGFRFBVJKH-BTJKTKAUSA-N
    InChI
    1S/C18H20N2O.C4H4O4/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21;5-3(6)1-2-4(7)8/h3-4,6-9H,5,10-11,19H2,1-2H3;1-2H,(H,5,6)(H,7,8)/bshow more
    Synonyms
    10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate
  9. Fostamatinib (R788), Tyrosine-protein kinase SYK inhibitor
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    Fostamatinib (R788), Tyrosine-protein kinase SYK inhibitor
    CAS: 901119-35-5 EC Number: 618-473-2 Formula: C23H26FN6O9P Molecular Weight: 580.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F129915
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    Technical Identifiers
    IUPAC Name
    [6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate
    SMILES
    CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
    InChIKey
    GKDRMWXFWHEQQT-UHFFFAOYSA-N
    InChI
    1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11Hshow more
    Synonyms
    J-517972 | FOSTAMATINIB [INN] | (6-((5-Fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-o...
  10. Syk Inhibitor(Isomer mixture), Inhibitor of spleen associated tyrosine kinase
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    Syk Inhibitor(Isomer mixture), Inhibitor of spleen associated tyrosine kinase
    CAS: 622387-85-3 PubChem CID: 24906266 Formula: C18H15N3O3S Molecular Weight: 353.39
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% mixture of isomers
    Out of Stock Item #: S274810
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    IUPAC Name
    3-[(1-methylindol-3-yl)methylidene]-2-oxo-1H-indole-5-sulfonamide
    SMILES
    CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC(=C4)S(=O)(=O)N)NC3=O
    InChIKey
    MLKHXLFEYOOYEY-UHFFFAOYSA-N
    InChI
    1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)
    Synonyms
    3-(1-METHYLINDOL-3-YLMETHYLENE)-2-OXO-2,3-DIHYDROINDOLE-5-SULFONICACIDAMIDE | 3-[(1-methyl-1H-indol-3-yl)methylidene]...
  11. BAY-61-3606
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    BAY-61-3606
    CAS: 648903-57-5 PubChem CID: 11784504 Formula: C20H20Cl2N6O3 Molecular Weight: 463.32
    10mM in DMSO
    In Stock Item #: B425289
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    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide;dihydrochloride
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl
    InChIKey
    SPMFEULFGGPQLN-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);2*show more
    Synonyms
    MS-28520 | 2-(7-(3,4-Dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide dihydrochloride | BAY 61-3606 (di...
  12. BAY 61-3606 dihydrochloride
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    BAY 61-3606 dihydrochloride
    CAS: 648903-57-5 PubChem CID: 11784504 Formula: C20H20Cl2N6O3 Molecular Weight: 463.32
    ≥98%
    In Stock Item #: B413704
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    2-[[7-(3,4-dimethoxyphenyl)imidazo[1,2-c]pyrimidin-5-yl]amino]pyridine-3-carboxamide;dihydrochloride
    SMILES
    COC1=C(C=C(C=C1)C2=CC3=NC=CN3C(=N2)NC4=C(C=CC=N4)C(=O)N)OC.Cl.Cl
    InChIKey
    SPMFEULFGGPQLN-UHFFFAOYSA-N
    InChI
    1S/C20H18N6O3.2ClH/c1-28-15-6-5-12(10-16(15)29-2)14-11-17-22-8-9-26(17)20(24-14)25-19-13(18(21)27)4-3-7-23-19;;/h3-11H,1-2H3,(H2,21,27)(H,23,24,25);2*show more
    Synonyms
    MS-28520 | 2-(7-(3,4-Dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide dihydrochloride | BAY 61-3606 (di...
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