Notch
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75 products
Popular Products
- LumiflavineSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%◐ .Made to order · 8–12 wks Item #: L338492View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7,8,10-trimethylbenzo[g]pteridine-2,4-dione
- SMILES
- CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)C
- InChIKey
- KPDQZGKJTJRBGU-UHFFFAOYSA-N
- InChI
- 1S/C13H12N4O2/c1-6-4-8-9(5-7(6)2)17(3)11-10(14-8)12(18)16-13(19)15-11/h4-5H,1-3H3,(H,16,18,19)
- Synonyms
- 7,8,10-trimethyl-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione | 7,8,10-Trimethylbenzo(g)pteridine-2,4,(3H,10H)-dione | BE...
- RO4929097, Gamma-secretase inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: R127403View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide
- SMILES
- CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
- InChIKey
- OJPLJFIFUQPSJR-INIZCTEOSA-N
- InChI
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- Synonyms
- NCGC00263162-01 | Propanediamide, N-((7S)-6,7-dihydro-6-oxo-5H-dibenz(b,d)azepin-7-yl)-2,2-dimethyl-N'-(2,2,3,3,3-pen...
- Procyanidin B2 3,3′-di-O-gallate● In Stock — US Item #: P350101View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
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- SMILES
- C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O)O)O)C7=CC(=C(C=C7)O)O)OC(=O)C8=CC(=C(C(=C8)O)O)O
- InChIKey
- KTLUHRSHFRODPS-RIQPQZJCSA-N
- InChI
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- Synonyms
- CHEBI:172846 | Procyanidin B2 3,3'-di-O-gallate | 3,3'-Digalloylprocyanidin B2 | Proanthocyanidin B2 3,3'-O-gallate |...
- Carvacrol, Channel blocker of TRPM7;Activator of TRPV3Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US Item #: C107162View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-methyl-5-propan-2-ylphenol
- SMILES
- CC1=C(C=C(C=C1)C(C)C)O
- InChIKey
- RECUKUPTGUEGMW-UHFFFAOYSA-N
- InChI
- 1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3
- Synonyms
- 2-methyl-5-propan-2-ylphenol | 2-methyl-5-propan-2-yl-phenol | AKOS000120828 | F8889-1978 | MB00118 | Oxycymol | 9B1J...
- Valproic acid, Inhibitor of histone deacetylase 1Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: V298968View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-propylpentanoic acid
- SMILES
- CCCC(CCC)C(=O)O
- InChIKey
- NIJJYAXOARWZEE-UHFFFAOYSA-N
- InChI
- 1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
- Synonyms
- Depakene | Depakin chrono | EC 202-777-3 | VALPROIC ACID | VALPROIC ACID [EP MONOGRAPH] | (n-C3H7)2CHCOOH | Nu-Valpro...
- LY-411575CAS: 209984-57-6 Formula: C26H23F2N3O4 Molecular Weight: 479.48Solid ≥98%● In Stock — US Item #: L125846View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
- SMILES
- CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)C(C4=CC(=CC(=C4)F)F)O
- InChIKey
- ULSSJYNJIZWPSB-CVRXJBIPSA-N
- InChI
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- Synonyms
- AC-32717 | LY 411,575 | N(2)-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-N-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibe...
- YO-01027● In Stock — US Item #: Y129283View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
- SMILES
- CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F
- InChIKey
- QSHGISMANBKLQL-OWJWWREXSA-N
- InChI
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- Synonyms
- Dibenzazepine (Deshydroxy LY 411575) | NCGC00263188-03 | SB47619 | SCHEMBL3046688 | C26H23F2N3O3 | SW219340-1 | EX-A0...
- Psoralidin● In Stock — US Item #: P168140View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
- SMILES
- CC(=CCC1=CC2=C(C=C1O)OC(=O)C3=C2OC4=C3C=CC(=C4)O)C
- InChIKey
- YABIJLLNNFURIJ-UHFFFAOYSA-N
- InChI
- 1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3,5-9,21-22H,4H2,1-2H3
- Synonyms
- 3,9-dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one | UNII-G16ZUQ069L | BDBM246524 | HY...
- DAPTCAS: 208255-80-5 Formula: C23H26F2N2O4 Molecular Weight: 432.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: D126677View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
- SMILES
- CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F
- InChIKey
- DWJXYEABWRJFSP-XOBRGWDASA-N
- InChI
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- Synonyms
- Glycine, N-[2-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, 1,1-dimethylethyl ester, (2S)- | MRF-0000012 | (S)-tert...
- SAHM1 TFACAS: 2050906-89-1(free) Formula: C96H163N36O25SF3 Molecular Weight: 2310.58◐ .Made to order · 8–12 wks Item #: S320067View ProductPricing & Pack Sizes
Technical Identifiers
- FLI-06● In Stock — US Item #: F275654View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
- SMILES
- CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4
- InChIKey
- SWWVFYHSSOWZMF-UHFFFAOYSA-N
- InChI
- 1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
- Synonyms
- Cyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
- Prednisone 21-acetate● In Stock — US Item #: P302294View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
- SMILES
- CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)C=CC34C)C)O
- InChIKey
- MOVRKLZUVNCBIP-RFZYENFJSA-N
- InChI
- show more
- Synonyms
- 17-Hydroxy-3,11,20-trioxopregna-1,4-dien-21-yl acetate, (17.alpha.)- # | 4-08-00-03532 (Beilstein Handbook Reference)...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the Notch listing put together?
It draws on reported Notch annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Notch modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Notch entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Notch compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Notch work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Notch compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Notch compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.