Lincomycin HCl - 10mM in DMSO , CAS No.859-18-7

CAS: 859-18-7 Cat. No.: L408713 Molecular Weight: 443 EC Number: 212-726-7
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GRADE & PURITY 10mM in DMSO
Synonyms
NSC 70731 | methyl 6,​8-​dideoxy-​6-​[[[(2S,​4R)​-​1-​methyl-​4-​propyl-​2-​pyrrolidinyl]​carbonyl]​amino]​-​1-​thio-D-​erythro-​α-​D-​galacto-​octopyranoside,hydrochloride (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
L408713-1ml
2

$238.90

$347.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Information

Lincomycin hydrochloride (Lincocin, NSC 70731) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
In vitro


In vivo


Cell Data

cell lines:MDA-MB-361, MDA-MB-231, MDA-MB-468, BT549, LNCap, A549, H1975, H157, H460, U87MG, A498, 786-O, HCT116, MG63, Rat1, HEK293, and HeLa

Concentrations:

Incubation Time:

Powder Purity:≥95%

Specifications

Synonyms
NSC 70731 | methyl 6, ​8-​dideoxy-​6-​[[[(2S, ​4R)​-​1-​methyl-​4-​propyl-​2-​pyrrolidinyl]​carbonyl]​amino]​-​1-​thio-D-​erythro-​α-​D-​galacto-​octopyranoside, hydrochloride (1:1)
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Lincomycin hydrochloride (Lincocin, NSC 70731) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@@H](C)O.Cl
Alternate CAS 7179-49-9
Molecular Weight 443
Reaxy-Rn 24870211
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24870211&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Documents & Articles
Citations of This Product
References
1. Fan Yunfeng, Liu Zhimin, Wang Jie, Cui Chen, Hu Leqian.  (2022)  An “off–on” electrochemiluminescence aptasensor for determination of lincomycin based on CdS QDs/carboxylated g-C3N4.  MICROCHIMICA ACTA,  190  (1): (1-9).  [PMID:36477444] [10.1007/s00604-022-05587-w]
2. Zhi-feng Cai, Hao-yang Li, Xian-song Wang, Can Min, Jia-qi Wen, Rui-xin Fu, Zi-yue Dai, Jing Chen, Ming-zhu Guo, Hui-juan Yang, Ping-ping Bai, Xiao-mi Lu, Tao Wu, Ying Wu.  (2022)  Highly luminescent copper nanoclusters as temperature sensors and “turn off” detection of oxytetracycline.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2022.129202]
3. Yu-yu Guo, Yu-rui Hu, Shao-ke Chen, Ming-zhu Guo, Yi-ting Zhang, Xin-rui Han, Shen Zhang.  (2021)  Facile one-pot synthesis of tannic acid-stabilized fluorescent copper nanoclusters and its application as sensing probes for chlortetracycline based on inner filter effect.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2021.127962]
4. Gongxi Qiao, Gui Chen, Qin Wen, Wanqiang Liu, Jinwei Gao, Zhiqiang Yu, Qianming Wang.  (2020)  Rapid conversion from common precursors to carbon dots in large scale: Spectral controls, optical sensing, cellular imaging and LEDs application.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:32682119] [10.1016/j.jcis.2020.07.034]
5. Yumin Leng, Fang Hu, Chunhua Ma, Chenxi Du, Linfeng Ma, Jiao Xu, Qiyuan Lin, Zhipei Sang, Zhiwen Lu.  (2019)  Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl4 and NaOH.  RSC Advances,  (48): (28248-28252).  [PMID:35530481] [10.1039/C9RA04095A]
6. Pengcheng Xing, Di Wu, Jingshuai Chen, Jiming Song, Changjie Mao, Yuanhao Gao, Helin Niu.  (2019)  A Cd-MOF as a fluorescent probe for highly selective, sensitive and stable detection of antibiotics in water.  ANALYST,  144  (8): (2656-2661).  [PMID:30843538] [10.1039/C8AN02442A]
7. Qiong Ouyang, Fangying Kou, Nuanqin Zhang, Jintao Lian, Guoquan Tu, Zhanqiang Fang.  (2019)  Tea polyphenols promote Fenton-like reaction: pH self-driving chelation and reduction mechanism.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2019.02.078]
8. Bo Gao, Shaonan Dong, Jiadong Liu, Lifen Liu, Qiqi Feng, Na Tan, Tingting Liu, Longli Bo, Lei Wang.  (2016)  Identification of intermediates and transformation pathways derived from photocatalytic degradation of five antibiotics on ZnIn2S4.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2016.07.029]
9. Xiuzhong Wang, Shanshan Dong, Panpan Gai, Rui Duan, Feng Li.  (2016)  Highly sensitive homogeneous electrochemical aptasensor for antibiotic residues detection based on dual recycling amplification strategy.  BIOSENSORS & BIOELECTRONICS,      [PMID:27040941] [10.1016/j.bios.2016.03.055]
10. Hui Zhao, Zhen Wei, Shuxin Xu, Minjie Tang, Liandong Deng, Jianhua Zhang, Anjie Dong.  (2015)  Retracted Article: Preparation and Properties of Polymer Micelle-embedded Nanofibrous Membranes for Dual-drug Co-delivery and Multistep Release.  RSC Advances,      [PMID:] [10.1039/C5RA03345D]
11. Yin-Xia Sun, Bo-Tao Ji, Jiang-Hai Chen, Li-Ping Liu, Lu-Lu Gao, Zhe-Peng Deng, Yu Sun, Jian-Jun Wang, Biao Zhao, Jin-Guo Li.  (2024)  A smartphone-integrated bimetallic ratiometric fluorescent probe for specific visual detection of tetracycline antibiotics in food samples and latent fingerprinting.  FOOD CHEMISTRY,      [PMID:39486281] [10.1016/j.foodchem.2024.141782]
12. Yiyao Liu, Menglong Liu, Jingyi Xiao, Yi Ren, Jinyang Li, Jiayan Gao, Litao Chen, Xue Gao.  (2025)  A ratiometric fluorescence biosensor based on enzyme-cascade signal amplification technology for the detection of lincomycin.  FOOD CONTROL,      [PMID:] [10.1016/j.foodcont.2025.111344]
13. Qiaonan Wang, Mingyao Yu, Han Dong, Jingjing Duan, Yanxia Ding, Jinxiao Wang, Yujie Guo, Yaqian Huang, Tao Zhang, Xiaoxing Dong, Fengzhi Piao, Zhixin Guo.  (2026)  Abscisic acid confers antibiotic stress tolerance in cucumber by alleviating antibiotic phytotoxicity and decreasing the levels of antibiotic and antibiotic resistance genes.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:41506203] [10.1016/j.jhazmat.2026.141060]
14. Qinghua Wang, Dan Li, Yue Wu, Yang Zhang, Dongjing Wang, Xiuwu Lian, Zhongshun Huang, Huiying Li, Yunchong Ma, Yilin Li, Jiangyong Zeng, Lijing Cao, Honglei Ding.  (2026)  Characteristics of Mycoplasma synoviae Strains Isolated From Layer Eggs and Broiler Knee Joints or Foot Pads Mainly in Chongqing, China.  Transboundary and Emerging Diseases,  2026  (1): (2299833).  [PMID:] [10.1155/tbed/2299833]
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