Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC 50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II.
| Isomeric SMILES | C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4 |
|---|---|
| WGK Germany | 3 |
| Molecular Weight | 272.3 |
| Reaxy-Rn | 25226619 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25226619&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 230°C |
|---|
| 1. Xiong Zhang, Chen Feng, Yimao Li, Chenlin Su, Shuxin Zhao, Shengdi Su, Feng Yu, Ji LI. (2021) An investigation on nephrotoxicity of Aristolactam I induced epithelial-mesenchymal transition on HK-2 cells. TOXICON, [PMID:34391786] [10.1016/j.toxicon.2021.08.005] |
| 2. Ji Li, Mincheng Zhang, Yong Mao, Yimao Li, Xiaoxia Zhang, Xuehan Peng, Feng Yu. (2017) The potential role of aquaporin 1 on aristolochic acid I induced epithelial mesenchymal transition on HK-2 cells. JOURNAL OF CELLULAR PHYSIOLOGY, 233 (6): (4919-4925). [PMID:29215709] [10.1002/jcp.26310] |
| 3. Shi Yongjing, Zheng Xiaodong, Peng Hui, Xu Chenqi, Sun Rui, Tian Zhigang, Sun Haoyu, Wang Xianwei. (2024) The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling. Cancer Immunology Research, [PMID:38990095] [10.1158/2326-6066.CIR-23-1061] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
