Methylophiopogonanone B - ≥99% , CAS No.74805-91-7

CAS: 74805-91-7 Cat. No.: M648019 Molecular Weight: 328.36 EC Number: 813-739-6 PubChem CID: 46886723

GRADE & PURITY ≥99%

Synonyms

AKOS032948998 | (3R)-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-2,3-dihydrochromen-4-one | 8-Methylophiopogonanone B | MS-24920 | DTXSID101313976 | (3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-4H-1-benzopyran-4-one |

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas , shows high antioxidant ability. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation .

Form:Solid

Specifications

Synonyms

AKOS032948998 | (3R)-5, 7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6, 8-dimethyl-2, 3-dihydrochromen-4-one | 8-Methylophiopogonanone B | MS-24920 | DTXSID101313976 | (3R)-2, 3-Dihydro-5, 7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6, 8-dimethyl-4H-1-benzopyran-4-one |

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas , shows high antioxidant ability. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via a

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CC1=C(C(=C2C(=C1O)C(=O)C(CO2)CC3=CC=C(C=C3)OC)C)O
• IUPAC Name: (3R)-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-2,3-dihydrochromen-4-one
• InChIKey: UFMAZRUMVFVHLY-CYBMUJFWSA-N
• INCHI: 1S/C19H20O5/c1-10-16(20)11(2)19-15(17(10)21)18(22)13(9-24-19)8-12-4-6-14(23-3)7-5-12/h4-7,13,20-21H,8-9H2,1-3H3/t13-/m1/s1
• Isomeric SMILES: CC1=C(C(=C2C(=C1O)C(=O)[C@@H](CO2)CC3=CC=C(C=C3)OC)C)O
• Alternate CAS: 74805-91-7
• PubChem CID: 46886723
• MeSH Entry Terms: 5,7-dihydroxy-6,8-dimethyl-3-(4-methoxybenzyl)chroman-4-one;methylophiopogonanone B
• Molecular Weight: 328.36

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Class Homoisoflavonoids
      • Subclass Homoisoflavans

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Class: Homoisoflavonoids
• Subclass: Homoisoflavans
• Intermediate Tree Nodes: Not available
• Direct Parent: Homoisoflavanones
• Alternative Parents: Chromones Phenoxy compounds Methoxybenzenes Aryl alkyl ketones Anisoles Phenols Alkyl aryl ethers Vinylogous acids Oxacyclic compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Homoisoflavanone - Chromone - Chromane - Benzopyran - 1-benzopyran - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Aryl alkyl ketone - Aryl ketone - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Ketone - Organoheterocyclic compound - Ether - Oxacycle - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as homoisoflavanones. These are homoisoflavonoids with a structure based on the chromanone system. Chromanone is a bicyclic compound consisting of a 3,4-dihydro-1-benzopyran, which bears a ketone group at the 4-position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (304.54 mM; Need ultrasonic)
• Molecular Weight: 328.400 g/mol
• XLogP3: 3.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 328.131 Da
• Monoisotopic Mass: 328.131 Da
• Topological Polar Surface Area: 76.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 445.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1