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MPBH(4-(4-N-maleimidophenyl)butyric acid hydrazide) , CAS No.M638944
AVAILABLE TO ORDER
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Product introduction：
MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
Features of MPBH:
• Reactive groups:maleimide andhydrazide
• Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
• Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable)
• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
• Reactive Moiety:Amine,Hydrazide,Maleimide
• Crosslinker Type:Heterobifunctional
• Form:Powder
• Spacer:Medium(10 to 30 Å)
• Labeling Method:Chemical Labeling
• Spacer Arm Length:17.9 Å
Features of MPBH:
• Reactive groups:maleimide andhydrazide
• Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
• Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable)
• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
• Reactive Moiety:Amine,Hydrazide,Maleimide
• Crosslinker Type:Heterobifunctional
• Form:Powder
• Spacer:Medium(10 to 30 Å)
• Labeling Method:Chemical Labeling
• Spacer Arm Length:17.9 Å
Specifications
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties
| Reactivity | Carbohydrate-Sulfhydryl |
|---|
Names and Identifiers
| Molecular Weight | 309.75 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Solubility | DMF,DMSO |
|---|
Solution Calculators
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