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· · COA & SDS available for every product · Same-day shipping on in-stock items N⁶,2′-O-Dibutyryladenosine 3′,5′ -cyclic monophosphate sodium salt - ≥97%(HPLC) , CAS No.16980-89-5
Synonyms
Dibutyryl cAMP (sodium salt);DBcAMP (sodium salt) | InChI=1/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H | Actosin | Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt | Actosin (TN) | STK803270 | EINECS 243-065-2 | MLS0022071
Shipped In
Ice chest + Ice pads
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Why this grade ≥97%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Bucladesine is a membrane permeable selective activator of PKA.
Specifications Synonyms
Dibutyryl cAMP (sodium salt);DBcAMP (sodium salt) | InChI=1/C6H10O2/c7-6-4-2-1-3-5-8-6/h1-5H | Actosin | Adenosine, N-(1-oxobutyl)-, cyclic 3', 5'-(hydrogen phosphate) 2'-butanoate, monosodium salt | Actosin (TN) | STK803270 | EINECS 243-065-2 | MLS0022071
Specifications & Purity
≥97%(HPLC)
Biochemical and Physiological Mechanisms
Cell-permeable analog of cAMP; activates cAMP-dependent protein kinases. Promotes differentiation of dopaminergic neurons (iDA) from hPSCs in combination with other reagents.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504769482 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504769482 Canonical Smiles CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+] IUPAC Name sodium;[(4aR,6R,7R,7aR)-6-[6-(butanoylamino)purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl] butanoate InChIKey KRBZRVBLIUDQNG-JBVYASIDSA-M INCHI 1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1 Isomeric SMILES CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@H]4[C@H](O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+] WGK Germany 2 RTECS ES5055500 Molecular Weight 491.37 Reaxy-Rn 38305031 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38305031&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Nucleosides, nucleotides, and analogues Class Purine nucleotides Subclass Cyclic purine nucleotides Intermediate Tree Nodes Not available Direct Parent 3',5'-cyclic purine nucleotides Alternative Parents Pentose phosphates Glycosylamines Monosaccharide phosphates Purines and purine derivatives N-arylamides Fatty acid esters Organic phosphoric acids and derivatives Fatty amides N-substituted imidazoles Pyrimidines and pyrimidine derivatives Imidolactams Oxolanes Heteroaromatic compounds Carboxylic acid esters Secondary carboxylic acid amides Oxacyclic compounds Azacyclic compounds Monocarboxylic acids and derivatives Organic oxides Organic sodium salts Carbonyl compounds Organic zwitterions Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents 3',5'-cyclic purine ribonucleotide - Pentose phosphate - Glycosyl compound - N-glycosyl compound - Monosaccharide phosphate - Imidazopyrimidine - Purine - N-arylamide - Fatty acid ester - Fatty amide - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Pyrimidine - Imidolactam - Fatty acyl - Imidazole - Heteroaromatic compound - Azole - Oxolane - Carboxylic acid ester - Secondary carboxylic acid amide - Carboxamide group - Azacycle - Organoheterocyclic compound - Oxacycle - Monocarboxylic acid or derivatives - Organic alkali metal salt - Carboxylic acid derivative - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Organic oxygen compound - Organic sodium salt - Organic zwitterion - Organic salt - Carbonyl group - Organonitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 3',5'-cyclic purine nucleotides. These are purine nucleotides in which the oxygen atoms linked to the C3 and C5 carbon atoms of the ribose moiety are both bonded the same phosphorus atom of the phosphate group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 49.14, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 49.14, Max Conc. mM: 100 Sensitivity Heat sensitive Molecular Weight 491.400 g/mol XLogP3 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 11 Rotatable Bond Count 8 Exact Mass 491.118 Da Monoisotopic Mass 491.118 Da Topological Polar Surface Area 167.000 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 765.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 4 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
Citations of This Product References 1. Fen Wang, Jinping Zhang, Qian Zhang, Zhangyong Song, Caiyan Xin. (2024) Antifungal activities of Equol against Candida albicans in vitro and in vivo. Virulence, [PMID:39267283 ] [10.1080/21505594.2024.2404256 ] 2. Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming-Liang He. (2025) Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain. ADVANCED MATERIALS, [PMID:40619836 ] [10.1002/adma.202508464 ]
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Reconstitution Calculator Reviews Related Products Adenosine 2′:3′-cyclic monophosphate sodium salt - ≥97% , CAS No.37063-35-7
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1-O-hexadecyl-sn-glycero-2,3-cyclic-phosphate (ammonium salt) - ≥99% , CAS No.799268-68-1
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Dibutyryl-cAMP (Bucladesine) - 10mM in DMSO , CAS No.16980-89-5
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