N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride(TMPD) - ≥98% , CAS No.637-01-4

CAS: 637-01-4 Cat. No.: T106470 Molecular Weight: 237.17 Beilstein Registry Number: 7442241 EC Number: 211-274-8 PubChem CID: 71561

GRADE & PURITY ≥98%

Synonyms

TMPPD | MFCD00012482 | NSC 36730 | UNII-66W8HKA51X | AC-37044 | Q27264036 | M710 | 1,4-Bis(dimethylamino)benzene dihydrochloride | 66W8HKA51X | TMPD dihydrochloride | Halon 1011 | TETRAMETHYL-1,4-PHENYLENEDIAMINE DIHYDROCHLORIDE | A834480 | NSC36730 | NSC

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride(TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. TMPD undergoes one-electron oxidation by the heme peroxidase higher oxidation states (compounds I and II) producing a highly colored product that absorbs at 611 nm. Thus, the stoichiometry of oxidation is 2 moles of TMPD oxidized per mole of hydroperoxide reduced by the peroxidase. The extinction coefficient of the oxidized TMPD at 611 nm is 12,200.2 TMPD is also used for the detection of peroxidases on polyacrylamide gels.
An oxidizable compound

Test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms.; For oxidase reagent, use a 1% aqueous solution of N,N,N′,N′-Tetramethyl-p-phenylenediamine dihydrochloride

Specifications

Synonyms

TMPPD | MFCD00012482 | NSC 36730 | UNII-66W8HKA51X | AC-37044 | Q27264036 | M710 | 1, 4-Bis(dimethylamino)benzene dihydrochloride | 66W8HKA51X | TMPD dihydrochloride | Halon 1011 | TETRAMETHYL-1, 4-PHENYLENEDIAMINE DIHYDROCHLORIDE | A834480 | NSC36730 | NSC

Specifications & Purity

≥98%

Storage

Store at 2-8°C, Protected from light, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CN(C)C1=CC=C(C=C1)N(C)C.Cl.Cl
• IUPAC Name: 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine;dihydrochloride
• InChIKey: FBHKTSXMTASXFJ-UHFFFAOYSA-N
• INCHI: 1S/C10H16N2.2ClH/c1-11(2)9-5-7-10(8-6-9)12(3)4;;/h5-8H,1-4H3;2*1H
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)N(C)C.Cl.Cl
• WGK Germany: 3
• PubChem CID: 71561
• Molecular Weight: 237.17
• Beilstein: 7442241
• Reaxy-Rn: 5132096

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Tertiary amines
          • Level6 Tertiary alkylarylamines
            • Level7 Dialkylarylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines - Tertiary alkylarylamines
• Direct Parent: Dialkylarylamines
• Alternative Parents: Aniline and substituted anilines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aniline or substituted anilines - Dialkylarylamine - Benzenoid - Monocyclic benzene moiety - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as dialkylarylamines. These are aliphatic aromatic amines in which the amino group is linked to two aliphatic chains and one aromatic group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in DMSO (~1.7 mg/ml), water (50 mg/ml), and PBS (pH 7.2).,Dissolved in water
• Sensitivity: Moisture and Light sensitive
• Melt Point(°C): 224 °C(dec.)
• Molecular Weight: 237.170 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 236.085 Da
• Monoisotopic Mass: 236.085 Da
• Topological Polar Surface Area: 6.500 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 108.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

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