GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10mM in DMSO
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Information
Napabucasin (BBI608) is an orally availableStat3and cancer cell stemness inhibitor. In vitro
Napabucasin downregulates stemness gene expression driven by Stat3 and cancer stemness properties, and effectively inhibits self-renewal of stemness-high cancer cells with IC50 ranged from 0.291~1.19 μM, on inhibition on normal stem cells.
In vivo
In mice bearing PaCa-2 xenografts, Napabucasin (20 mg/kg, i.p.) significantly inhibits tumor growth, relapse and metastasis. Cell Data
cell lines：
Concentrations：~2 μM
Incubation Time：72 h
Powder Purity:≥99%
Specifications
Synonyms
BBI608 | 2-acetylnaphtho[2, 3-b]furan-4, 9-dione
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Napabucasin (BBI608) is an orally available Stat3 and cancer cell stemness inhibitor.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
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