Nedaplatin - ≥99% , CAS No.95734-82-0

CAS: 95734-82-0 Cat. No.: N129652 Molecular Weight: 303.17 EC Number: 111-811-5 PubChem CID: 6917890

GRADE & PURITY ≥99%

Synonyms

Aqupla | (Glycolato-O,O')diammineplatinum(II) | cis-Diammine(glycolato)platinum(II)

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units with IC50 of 94 μM
A platinum complex that has potent antineoplatic activity

Specifications

Synonyms

Aqupla | (Glycolato-O, O')diammineplatinum(II) | cis-Diammine(glycolato)platinum(II)

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Nedaplatin is a platinum complex that has potent antineoplastic activity.Platinum compound. Derivative of cisplatin. Displays antineoplastic and antitumor effects in vitro .

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 504764342
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764342
• Canonical Smiles: C(C(=O)O)O.N.N.[Pt]
• IUPAC Name: azane;2-hydroxyacetic acid;platinum
• InChIKey: ZAXCMPAWRCMABN-UHFFFAOYSA-N
• INCHI: 1S/C2H4O3.2H3N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H3
• Isomeric SMILES: C(C(=O)O)O.N.N.[Pt]
• PubChem CID: 6917890
• MeSH Entry Terms: (glycolato-O,O')diammineplatinum II;254-S;CGDP-II;cis-diammine(glycolato)platinum II;nedaplatin;NSC 375101D;NSC-375101D
• Molecular Weight: 303.17

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Hydroxy acids and derivatives
      • Subclass Alpha hydroxy acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Hydroxy acids and derivatives
• Subclass: Alpha hydroxy acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha hydroxy acids and derivatives
• Alternative Parents: Organic transition metal salts Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds Amines
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-hydroxy acid - Organic transition metal salt - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Carbonyl group - Amine - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha hydroxy acids and derivatives. These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water at 10 mg/mL.
• Sensitivity: light sensitive
• Molecular Weight: 305.200 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 305.034 Da
• Monoisotopic Mass: 305.034 Da
• Topological Polar Surface Area: 59.500 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 44.100
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

References

1. Sai-Nan Qin, Yi-Xue Zhang, Yi-Jie Cao, Ting Wan, Yi-Yang Zhou, Shan-Shan Su, Yu-Qiong Guo, Jian-Jun Sun, Kalle Salminen.  (2026)  A self-assembled electrochemical aptasensor for one-step rapid detection of cisplatin in blood via aptamer conformational change.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2026.116962]