NH2-PEG-NH2 - average Mw2000 , CAS No.956496-54-1

CAS: 956496-54-1 Cat. No.: N590849
AVAILABLE TO ORDER
GRADE & PURITY average Mw2000
Synonyms
Amine-PEG-Amine | PEG Diamine | PEG-Bisamine
Storage
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
250mg
N590849-250mg
5
$19.90
1g
N590849-1g
1
$69.90
5g
N590849-5g
1
$167.90
25g
N590849-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$669.90
Enter a quantity for the sizes you want to add.
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Why this grade

average Mw2000 for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Application:

Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound.NH2-PEG-NH2 is a homobibifunctional PEG derivative. It has a linear bifunctional PEG crosslinker with active primary amine or NH2 groups, which can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds.The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.NH2-PEG-NH2 can be dissolved in conventional aqueous solutions and most organic solvents, and can also inhibit the non-specific binding of charged molecules to the modified surface.

Specifications

Synonyms
Amine-PEG-Amine | PEG Diamine | PEG-Bisamine
Specifications & Purity
average Mw2000
Storage
Protected from light, Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

29 results found

Lot NumberCertificate TypeDateItem
H2329363Certificate of AnalysisJun 09, 2026 N590849
E2625367Certificate of AnalysisMar 06, 2026 N590849
E2625368Certificate of AnalysisMar 06, 2026 N590849
E2625369Certificate of AnalysisMar 06, 2026 N590849
E2625372Certificate of AnalysisMar 06, 2026 N590849
G2525489Certificate of AnalysisJul 17, 2025 N590849
G2525441Certificate of AnalysisJul 17, 2025 N590849
G2525440Certificate of AnalysisJul 17, 2025 N590849
G2525439Certificate of AnalysisJul 17, 2025 N590849
E2519374Certificate of AnalysisApr 30, 2025 N590849
E2519375Certificate of AnalysisApr 30, 2025 N590849
E2519393Certificate of AnalysisApr 30, 2025 N590849
E2519394Certificate of AnalysisApr 30, 2025 N590849
L2417546Certificate of AnalysisDec 10, 2024 N590849
L2417545Certificate of AnalysisDec 10, 2024 N590849
L2417547Certificate of AnalysisDec 10, 2024 N590849
H2402400Certificate of AnalysisJul 17, 2024 N590849
H2402404Certificate of AnalysisJul 17, 2024 N590849
H2402405Certificate of AnalysisJul 17, 2024 N590849
F2411395Certificate of AnalysisMay 25, 2024 N590849
G2419046Certificate of AnalysisMay 25, 2024 N590849
F2411394Certificate of AnalysisMay 25, 2024 N590849
F2411393Certificate of AnalysisMay 25, 2024 N590849
F2411392Certificate of AnalysisMay 25, 2024 N590849
F2411391Certificate of AnalysisMay 25, 2024 N590849
C2414687Certificate of AnalysisMar 01, 2024 N590849
C2414688Certificate of AnalysisMar 01, 2024 N590849
H2329357Certificate of AnalysisAug 12, 2023 N590849
H2329367Certificate of AnalysisAug 12, 2023 N590849

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Chemical and Physical Properties
SensitivityMoisture sensitive;Light sensitive
Citations of This Product
References
1. Jiahao Chang, Liyin Yu, Jiao Lei, Xiaoli Liu, Chunxiao Li, Yali Zheng, Hong Chen.  (2023)  A multifunctional bio-patch crosslinked with glutaraldehyde for enhanced mechanical performance, anti-coagulation properties, and anti-calcification properties.  Journal of Materials Chemistry B,      [PMID:37888984] [10.1039/D3TB01724A]
2. Lin Yijie, Wang Junsong.  (2022)  Engineering sialic acid-coated mesoporous polydopamine nanomaterials for MRI-guided photothermal-enhanced synergistic effect chemodynamic lung cancer therapy.  Materials Express,  12  (12): (1444-1454).  [PMID:] [10.1166/mex.2022.2313]
3. Yulong Bai, Jingjin Zhao, Liangliang Zhang, Shulong Wang, Jing Hua, Shulin Zhao, Hong Liang.  (2022)  A Smart Near-Infrared Carbon Dot-Metal Organic Framework Assemblies for Tumor Microenvironment-Activated Cancer Imaging and Chemodynamic-Photothermal Combined Therapy.  Advanced Healthcare Materials,  11  (12): (2102759).  [PMID:35170255] [10.1002/adhm.202102759]
4. Jing Yang, Jinzhe Zhou, Yingying Zhao, Liangchen Zhu, Guanghong Luo, BuJun Ge.  (2021)  Hollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice.  International Journal of Nanomedicine,      [PMID:34675513] [10.2147/IJN.S317261]
5. Bo Zhang, Xiaofeng Wang, Dongfang Wang, Meng Guo, Cuihong Ren, Wenjuan Han, Hiroshi Uyama, Qian Li.  (2021)  Improved Antithrombogenicity of a Poly(lactic acid) Surface Grafted with Chondroitin Sulfate.  ACS Applied Bio Materials,      [PMID:35014308] [10.1021/acsabm.0c01629]
6. Lejiao Jia, Zhenyu Li, Dandan Zheng, Zhiying Li, Zhongxi Zhao.  (2020)  A targeted and redox/pH-responsive chitosan oligosaccharide derivatives based nanohybrids for overcoming multidrug resistance of breast cancer cells.  CARBOHYDRATE POLYMERS,      [PMID:33142574] [10.1016/j.carbpol.2020.117008]
7. Rong Zhang, Teng Jin, Yue Zhang, Xueqing Sui, Shiman Wu, Yue Wu, Dapeng Hao, Zhenwei Yao, Zhengze Yu, Xuejun Liu, Hua Zhang.  (2024)  Dynamic processes of positive/negative immune-vascular crosstalk loop via functional MRI-guided monitor.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.152674]
8. Dan Li, Mengyao Zhang, Yudai Huang, Xin Hu, Junqing Hu.  (2024)  FeNC with atomically dispersed iron atoms as a photosensitizer for combined photodynamic and photothermal therapy.  FlatChem,      [PMID:] [10.1016/j.flatc.2024.100663]
9. Ji-Chao Guo, Shi-Hui Deng, Shu-Min Zhou, Xuan Zhou, Jiajia Du, Si-Han Zhou, Qi-Hua Zhao, Zhong-Yan Cai, Xiaoxia Ren, Ming-jin Xie.  (2024)  Responsive ZIF-90 nanocomposite material: targeted delivery of 10-hydroxycamptothecine to enhance the therapeutic effect of colon cancer (HCT116) cells.  RSC Medicinal Chemistry,      [PMID:39149092] [10.1039/D3MD00725A]
10. Meixiang Zhang, Xinran Song, Yu Qin, Yuanyuan Peng, Shanshan Zhang, Wei Feng, Hui Huang, Yu Chen, Jianqiao Zhou.  (2025)  Single-atom–doped piezocatalyst induces copper-free cuproptosis in tumor therapy.  Science Advances,  11  (7):   [PMID:39951535] [10.1126/sciadv.adt8451]
11. Hao Liu, Haolin Chen, Xiaoying Liu, Luoqi Mo, Chao Chen, Zhouyi Guo, Zhiming Liu.  (2021)  Dual-responsive ultrathin 1T-phase niobium telluride nanosheet-based delivery systems for enhanced chemo-photothermal therapy.  Journal of Materials Chemistry B,  (38): (8109-8120).  [PMID:34494067] [10.1039/D1TB01469B]
12. Mengyuan Li, Jinling Guo, Jiaming Ge, Jingwen Yao, Lin Ma, Zheng Li, Xiangli Han, Ming Liu, Fei Tian, Jing Zhao.  (2025)  The Construction of Polyethylene Glycol-Folic Acid Modified Magnetic Layered Hydroxide Nanoplatform for Controlled Drug Delivery.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.57245]
13. Xiaohuan Guo, Bingbing Cai, Qi Fang, Yanyan Chen, Yuzhu Zhou, Zhixing Liang, Changchun Wen, Yan-Cheng Liu, Hong Liang.  (2025)  Norcantharidin/Cu2+ dual-depleting GSH nanocatalyst with pH-responsive for CT/CDT synergistic cancer therapy.  Materials Today Bio,      [PMID:40547489] [10.1016/j.mtbio.2025.101959]
14. Yuehao Gan, Qiyue Wang, Hui Du, Yuqi Wang, Dao Shi, Longfei Pan, Daishun Ling, Fangyuan Li.  (2025)  Metal-Ion-Activity Magnetic Nanoprobes for MRI Sensing of Cu2+ Levels in Tumor Malignancy.  Small,      [PMID:41050990] [10.1002/smll.202507307]
15. Xiaonan Wei, Chaoquan Lai, Xiaoyang Zhu, Aiyan Ji, Yeshan Qin, Shu Gao, Qiuyu Liu, Yonghao Li, Xuanyan Zhao, Hongyue Lou, Chunrong Qu, Zhen Cheng.  (2025)  Construction of 89Zr-Radiolabeled Melanin-Based Nanoprobes with FAP-Targeted Motifs for Tumor PET Imaging.  MOLECULAR PHARMACEUTICS,      [PMID:41111236] [10.1021/acs.molpharmaceut.5c01192]
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