Pacritinib citrate , Tyrosine-protein kinase JAK2 inhibitor, CAS No.1228923-42-9, Tyrosine-protein kinase JAK2 inhibitor

CAS: 1228923-42-9 Cat. No.: P671196 Molecular Weight: 664.7 EC Number: 875-958-3
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Synonyms
Pacritinib citrate | UNII-VJ2PH4NXX7 | Pacritinib citrate [WHO-DD] | Vonjo | Epjevy | SB-1518 CITRATE | CHEMBL5095049 | VJ2PH4NXX7 | 14,19-Dioxa-5,7,27-triazatetracyclo(19.3.1.12,6.18,12)heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene, 11-(2-(1-pyr
Storage
Room temperature
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
P671196-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$999.90
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Pacritinib citrate | UNII-VJ2PH4NXX7 | Pacritinib citrate [WHO-DD] | Vonjo | Epjevy | SB-1518 CITRATE | CHEMBL5095049 | VJ2PH4NXX7 | 14, 19-Dioxa-5, 7, 27-triazatetracyclo(19.3.1.12, 6.18, 12)heptacosa-1(25), 2, 4, 6(27), 8, 10, 12(26), 16, 21, 23-decaene, 11-(2-(1-pyr
Storage
Room temperature
Action Type
INHIBITOR
Mechanism of action
Tyrosine-protein kinase JAK2 inhibitor
Names and Identifiers
Canonical SmilesC1CCN(C1)CCOC2=C3COCC=CCOCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
IUPAC Name2-hydroxypropane-1,2,3-tricarboxylic acid;(16E)-11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaene
InChIKeyBAHHBHSHSRTKNK-BJILWQEISA-N
INCHI1S/C28H32N4O3.C6H8O7/c1-2-13-32(12-1)14-17-35-27-9-8-25-19-24(27)21-34-16-4-3-15-33-20-22-6-5-7-23(18-22)26-10-11-29-28(30-25)31-26;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-11,18-19H,1-2,12-17,20-21H2,(H,29,30,31);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b4-3+;
Isomeric SMILES C1CCN(C1)CCOC2=C3COC/C=C/COCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Molecular Weight 664.7
Reaxy-Rn 20404913
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20404913&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassTricarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentTricarboxylic acids and derivatives
Alternative Parents Phenol ethers  Alkyl aryl ethers  Alpha hydroxy acids and derivatives  N-alkylpyrrolidines  Pyrimidines and pyrimidine derivatives  Heteroaromatic compounds  Tertiary alcohols  Trialkylamines  Oxacyclic compounds  Dialkyl ethers  Carboxylic acids  Azacyclic compounds  Secondary amines  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkNot available
Substituents Tricarboxylic acid or derivatives - Phenol ether - Alkyl aryl ether - Alpha-hydroxy acid - Hydroxy acid - Pyrimidine - Benzenoid - N-alkylpyrrolidine - Heteroaromatic compound - Pyrrolidine - Tertiary alcohol - Tertiary aliphatic amine - Tertiary amine - Carboxylic acid - Dialkyl ether - Ether - Oxacycle - Azacycle - Secondary amine - Organoheterocyclic compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Amine - Carbonyl group - Alcohol - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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