Broad spectrum fluoroquinolone antibiotic agent. Inhibits DNA gyrase, topoisomerase II and topoisomerase IV. Shows bactericidal effects against both Gram-positive and Gram-negative bacteria in vivo. Orally active. Blood-brain barrier permeable.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
External Descriptors
methanesulfonate salt
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Jia-Yu Zeng, Yu-Qi Liang, Yan-Ni Wu, Xiao-Yi Wu, Jia-Ping Lai, Hui Sun. (2022) Synthesis and application of novel N, Si-carbon dots for the ratiometric fluorescent monitoring of the antibiotic balofloxacin in tablets and serum. RSC Advances, 12 (45):(29585-29594). [PMID:36320748][10.1039/D2RA02932D]
2.Qiang Zhang, Shengbao Duan, Yinong Huang, Jingjing Tian, Jia Hu. (2022) Dual-band fluorescence detection of double-stranded DNA with QDs-Mn2+-pefloxacin. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:35753193][10.1016/j.colsurfb.2022.112649]
4.Liang Wanjun, Liu Zhengqing, Li Dan, Wu Xiaoping, Liu Shaopu, He Youqiu. (2014) Quantum dots modified with the Al(III)-pefloxacin complex as a novel bioprobe for the sensitive turn-on and dual-fluorescence detection of dsDNA. MICROCHIMICA ACTA, 182 (1):(297-306). [PMID:][10.1007/s00604-014-1332-4]
5.Guohua Qi, Xingkang Diao, Yu Tian, Dan Sun, Yongdong Jin. (2024) Electroactivated SERS Nanoplatform for Rapid and Sensitive Detection and Identification of Tumor-Derived Exosome miRNA. ANALYTICAL CHEMISTRY, [PMID:39523538][10.1021/acs.analchem.4c04402]
6.Huang Xianzhi, Xia Ling, Li Gongke. (2024) Gold-grafted melamine sponge as surface-enhanced Raman spectroscopy substrate for enzyme-linked immunoassay of mycotoxins in cereal samples. MICROCHIMICA ACTA, 191 (12):(1-13). [PMID:39581912][10.1007/s00604-024-06831-1]
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