Pemetrexed disodium heptahydrate - Moligand™, 10 mM in Water , CAS No.357166-29-1

CAS: 357166-29-1 Cat. No.: P1494065 Molecular Weight: 597.49 EC Number: 639-569-0 PubChem CID: 135564751

GRADE & PURITY Moligand™, 10 mM in Water

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Pemetrexed disodium heptahydrate is a novel antifolate , the K i values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase ( TS ), dihydrofolate reductase ( DHFR ), and glycinamide ribonucleotide formyltransferase ( GARFT ), respectively.

Specifications

Specifications & Purity

Moligand™, 10 mM in Water

Storage

Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+]
• Alternate CAS: 150399-23-8,357166-29-1
• PubChem CID: 135564751
• MeSH Entry Terms: 231,514, LY;231514, LY;ALIMTA;Disodium, Pemetrexed;LY 231,514;LY 231514;LY-231,514;LY-231514;LY231514;MTA;N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid;pemetrexed;pemetrexed disodium
• Molecular Weight: 597.49

References

1. Kui Wang, Qi-Qi Wang, Mi-Ni Wang, Siyang Xing, Bolin Zhu, Ze-Hao Zhang.  (2019)  Supramolecular Amphiphilic Assembly Formed by the Complexation of Calixpyridinium with Alimta.  LANGMUIR,      [PMID:31203624] [10.1021/acs.langmuir.9b01336]