PF 04671536 hydrochloride - ≥98%(HPLC) , CAS No.1305116-67-9

CAS: 1305116-67-9 Cat. No.: P287242 Molecular Weight: 382.87 PubChem CID: 131954582
AVAILABLE TO ORDER
GRADE & PURITY ≥98%(HPLC)
Synonyms
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine hydrochloride
Storage
Room temperature,Desiccated
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
P287242-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$173.90
25mg
P287242-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$671.90
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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
5-Methyl-3-[[(2R)-4-(2-thiazolylmethyl)-2-morpholinyl]methyl]-3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-7-amine hydrochloride
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
Potent and selective PDE8B/8A inhibitor ( IC50values are 1.3 and 1.9 nM, respectively). Exhibits selectivity for PDE8A/B over other PDEs (IC50values are >10 μM) and a range of other targets. Increases glucose-dependent insulin secretion from human pacrea
Storage
Room temperature, Desiccated
Shipped In
Normal
Action Type
INHIBITOR
Purity
≥98%(HPLC)
Names and Identifiers
Canonical SmilesCC1=NC(=C2C(=N1)N(N=N2)CC3CN(CCO3)CC4=NC=CS4)N.Cl
IUPAC Name5-methyl-3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]triazolo[4,5-d]pyrimidin-7-amine;hydrochloride
InChIKeyKNBIGIZPAKPDTF-HNCPQSOCSA-N
INCHI1S/C14H18N8OS.ClH/c1-9-17-13(15)12-14(18-9)22(20-19-12)7-10-6-21(3-4-23-10)8-11-16-2-5-24-11;/h2,5,10H,3-4,6-8H2,1H3,(H2,15,17,18);1H/t10-;/m1./s1
PubChem CID 131954582
Molecular Weight 382.87

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D Structure
Interactive Chemical Structure Model





Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilitySolvent:water, Max Conc. mg/mL: 7.66, Max Conc. mM: 20 with gentle warming; Solvent:DMSO, Max Conc. mg/mL: 38.29, Max Conc. mM: 100
Solution Calculators
Reviews

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