Picrinine - ≥99% , CAS No.4684-32-6

CAS: 4684-32-6 Cat. No.: P650084 Formula: C₂₀H₂₂N₂O₃ Molecular Weight: 338.40 PubChem CID: 6738085

GRADE & PURITY ≥99%

Synonyms

Picrinine | FT-0698441 | B2703-092765 | Methyl 14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate | DTXSID30425161

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris . Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme

Form:Solid

IC50& Target:5-Lipoxygenase

Specifications

Synonyms

Picrinine | FT-0698441 | B2703-092765 | Methyl 14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate | DTXSID30425161

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris . Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme.

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

Canonical Smiles

CC=C1CN2C3CC1C(C45C3(NC6=CC=CC=C64)OC2C5)C(=O)OC

IUPAC Name

methyl 14-ethylidene-18-oxa-2,12-diazahexacyclo[9.6.1.19,15.01,9.03,8.012,17]nonadeca-3,5,7-triene-19-carboxylate

InChIKey

BDXYPHKGNUGUFG-UHFFFAOYSA-N

INCHI

1S/C20H22N2O3/c1-3-11-10-22-15-8-12(11)17(18(23)24-2)19-9-16(22)25-20(15,19)21-14-7-5-4-6-13(14)19/h3-7,12,15-17,21H,8-10H2,1-2H3

Isomeric SMILES

CC=C1CN2C3CC1C(C45C3(NC6=CC=CC=C64)OC2C5)C(=O)OC

Alternate CAS

4684-32-6

PubChem CID

6738085

MeSH Entry Terms

picrinine

Molecular Weight

338.40

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Indoles and derivatives
      • Subclass Pyridoindoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Indoles and derivatives
• Subclass: Pyridoindoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Beta carbolines
• Alternative Parents: Carbazoles Quinolizidines Indolines Piperidines Benzenoids Oxolanes Oxazolidines Methyl esters Hemiaminals Oxacyclic compounds Monocarboxylic acids and derivatives Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Beta-carboline - Carbazole - Quinolizidine - Dihydroindole - Piperidine - Benzenoid - Oxazolidine - Oxolane - Methyl ester - Carboxylic acid ester - Hemiaminal - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Azacycle - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Amine - Carbonyl group - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as beta carbolines. These are compounds containing a 9H-pyrido[3,4-b]indole moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 33.33 mg/mL (98.49 mM; ultrasonic and warming and heat to 60°C)

Frequently Asked Questions

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, protected from light, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 4684-32-6, the molecular formula is C20H22N2O3, and the molecular weight is 338.40 g/mol. InChIKey BDXYPHKGNUGUFG-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.