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Pinocembrin chalcone - ≥98% , CAS No.4197-97-1

CAS: 4197-97-1 Cat. No.: P691736 Molecular Weight: 256.25 PubChem CID: 6474295
COA
Pinocembrin chalcone - ≥98% CAS No(4197-97-1) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
3-Phenyl-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one | 2',4',6'-Trihydroxychalcone
Storage
Store at 2-8°C,Protected from light
Shipped In
Wet ice
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
P691736-1mg
2

$67.90

$101.90
Save $34.00 (33.37%)
5mg
P691736-5mg
2

$202.90

$304.90
Save $102.00 (33.45%)
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes.

Specifications

Synonyms
3-Phenyl-1-(2, 4, 6-trihydroxyphenyl)prop-2-en-1-one | 2', 4', 6'-Trihydroxychalcone
Specifications & Purity
≥98%
Storage
Store at 2-8°C, Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Canonical SmilesC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2O)O)O
IUPAC Name(E)-3-phenyl-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
InChIKeyLOYXTWZXLWHMBX-VOTSOKGWSA-N
INCHI1S/C15H12O4/c16-11-8-13(18)15(14(19)9-11)12(17)7-6-10-4-2-1-3-5-10/h1-9,16,18-19H/b7-6+
Isomeric SMILES C1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2O)O)O
Alternate CAS 4197-97-1
PubChem CID 6474295
MeSH Entry Terms 2',4',6'-trihydroxychalcone;pinocembrin chalcone
Molecular Weight 256.25

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClassLinear 1,3-diarylpropanoids
SubclassChalcones and dihydrochalcones
Intermediate Tree Nodes Not available
Direct Parent2'-Hydroxychalcones
Alternative Parents Cinnamylphenols  Acylphloroglucinols and derivatives  Styrenes  Benzoyl derivatives  Aryl ketones  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Vinylogous acids  Enones  Acryloyl compounds  Polyols  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents 2'-hydroxychalcone - Cinnamylphenol - Acylphloroglucinol derivative - Benzenetriol - Phloroglucinol derivative - Benzoyl - Aryl ketone - Styrene - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Benzenoid - Acryloyl-group - Vinylogous acid - Enone - Alpha,beta-unsaturated ketone - Ketone - Polyol - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organic oxide - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 2'-hydroxychalcones. These are organic compounds containing chalcone skeleton that carries a hydroxyl group at the 2'-position.
External Descriptors Chalcones and dihydrochalcones
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Slc5a1 Sodium/glucose cotransporter 1 (11 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc5a2 Sodium/glucose cotransporter 2 (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
J2510453Certificate of AnalysisAug 02, 2025 P691736
J2510454Certificate of AnalysisAug 02, 2025 P691736
Chemical and Physical Properties
Solubility2.56 mg/mL (9.99 mM), Sonication is recommended
SensitivityMoisture sensitive； light sensitive
Molecular Weight256.250 g/mol
XLogP33.200
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass256.074 Da
Monoisotopic Mass256.074 Da
Topological Polar Surface Area77.800 Ų
Heavy Atom Count19
Formal Charge0
Complexity321.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Solution Calculators
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