Pitstop ® 1-25 - ≥99% , CAS No.1419321-16-6

CAS: 1419321-16-6 Cat. No.: P276479 Molecular Weight: 405.47 PubChem CID: 75593424

GRADE & PURITY ≥99%

Synonyms

3-Sulfo-N-(benzyl)-1,8-naphthalimidepotassiumsalt

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Overview

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Synonyms

3-Sulfo-N-(benzyl)-1, 8-naphthalimidepotassiumsalt

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Novel, selective clathrin inhibitor. Inhibits the clathrin terminal domain (IC 50 = 6.9 μM). No inhibition seen with dynamin and other key clathrin mediated endocytosis pathway proteins. Low cell permeability. Related products Pitstop ® 2 , Pi

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥99%

Names and Identifiers

• Canonical Smiles: C1=CC=C(C=C1)CN2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)S(=O)(=O)[O-].[K+]
• IUPAC Name: potassium;2-benzyl-1,3-dioxobenzo[de]isoquinoline-5-sulfonate
• InChIKey: XOIYIOVSMFKQQC-UHFFFAOYSA-M
• INCHI: 1S/C19H13NO5S.K/c21-18-15-8-4-7-13-9-14(26(23,24)25)10-16(17(13)15)19(22)20(18)11-12-5-2-1-3-6-12;/h1-10H,11H2,(H,23,24,25);/q;+1/p-1
• Isomeric SMILES: C1=CC=C(C=C1)CN2C(=O)C3=CC=CC4=CC(=CC(=C43)C2=O)S(=O)(=O)[O-].[K+]
• PubChem CID: 75593424
• Molecular Weight: 405.47

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in DMSO