Poly (hexamethylene biguanide) hydrochloride（PHMB） - 20% in H2O , CAS No.32289-58-0

CAS: 32289-58-0 Cat. No.: P770156 EC Number: 608-723-9

GRADE & PURITY 20% in H2O

Synonyms

N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide | Poly (hexamethylene biguanide) | SCHEMBL24018755 | Polyhexamethylene Biguanidine HCl

Storage

Protected from light,Room temperature,Desiccated

Shipped In

Normal

Specifications

Synonyms

N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide | Poly (hexamethylene biguanide) | SCHEMBL24018755 | Polyhexamethylene Biguanidine HCl

Specifications & Purity

20% in H2O

Biochemical and Physiological Mechanisms

PHMB guanidine group has high activity and can make polymers positively charged. It is easily adsorbed by various bacteria and viruses that are negatively charged, thereby inhibiting the division function of bacteria and viruses, causing them to lose thei

Storage

Protected from light, Room temperature, Desiccated

Shipped In

Normal

Names and Identifiers

• Canonical Smiles: CC(=NCCCCCCNC(=NC)N)N
• IUPAC Name: N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide
• InChIKey: SAGIGHPRUJPLKX-UHFFFAOYSA-N
• INCHI: 1S/C10H23N5/c1-9(11)14-7-5-3-4-6-8-15-10(12)13-2/h3-8H2,1-2H3,(H2,11,14)(H3,12,13,15)
• Isomeric SMILES: CC(=NCCCCCCNC(=NC)N)N

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Guanidines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Guanidines
• Intermediate Tree Nodes: Not available
• Direct Parent: Guanidines
• Alternative Parents: Propargyl-type 1,3-dipolar organic compounds Carboximidamides Carboxamidines Imines Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Guanidine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Carboxylic acid amidine - Amidine - Hydrocarbon derivative - Imine - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as guanidines. These are compounds containing a guanidine moiety, with the general structure (R1R2N)(R3R4N)C=N-R5.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 213.320 g/mol
• XLogP3: -0.400
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 213.195 Da
• Monoisotopic Mass: 213.195 Da
• Topological Polar Surface Area: 88.800 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 210.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Gang Tang, Yuyang Tian, Junfan Niu, Jingyue Tang, Jiale Yang, Yunhao Gao, Xi Chen, Xuan Li, Huachen Wang, Yongsong Cao.  (2021)  Development of carrier-free self-assembled nanoparticles based on fenhexamid and polyhexamethylene biguanide for sustainable plant disease management.  GREEN CHEMISTRY,  23  (6): (2531-2540).  [PMID:] [10.1039/D1GC00006C]

2. Zou Peizhuo, Yang Qian, Wang Hailiang, Xie Guosi, Cao Zhi, Chen Xing, Gao Wen, Huang Jie.  (2020)  In vitro disinfection efficacy and clinical protective effects of common disinfectants against acute hepatopancreatic necrosis disease (AHPND)-causing Vibrio isolates in Pacific white shrimp Penaeus vannamei.  JOURNAL OF MICROBIOLOGY,  58  (8): (675-686).  [PMID:32720097] [10.1007/s12275-020-9537-1]

3. Wenbo Wu, Zutong Cui, Qing Li, Dongxue Ning, Xiujuan Liu, Bingbing Li, Zhiwei Liu, Jian Li, Tifeng Jiao.  (2026)  Self-assembled cross-linking composite electrospun nanofiber membranes: Synergistic antibacterial action and enhanced wound healing performance.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2026.139832]