Propafenone HCl - 10mM in DMSO , Beta-1 adrenergic receptor antagonist, CAS No.34183-22-7, Beta-1 adrenergic receptor antagonist

CAS: 34183-22-7 Cat. No.: P409024 Molecular Weight: 377.9 EC Number: 251-867-9

GRADE & PURITY 10mM in DMSO

Synonyms

1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Propafenone HCl Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.
In vitro

In vivo

Cell Data

cell lines：A549, H322, H3255, H358 H661, H1650, H1975, H1299, H596 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyms

1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1)

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ANTAGONIST

Mechanism of action

Beta-1 adrenergic receptor antagonist

Names and Identifiers

• Isomeric SMILES: CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl
• WGK Germany: 3
• RTECS: UH2833000
• Molecular Weight: 377.9
• Reaxy-Rn: 4343069
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4343069&ln=

Chemical and Physical Properties

• Melt Point(°C): 172-175°C

References

1. Zhang Yuecheng, Zhang Jie, Sun Lingbo, Tian Rui, Ma Hongyan.  (2022)  Ratiometric detection of propafenone hydrochloride with one-pot synthesized dual emissive carbon dots.  CHEMICAL PAPERS,  77  (1): (375-383).  [PMID:] [10.1007/s11696-022-02489-2]