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PROTAC MPS1 degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 ( Mps1 , TTK) , AURKA and AURKB , with DC 50 s of 42.0, 2.1 and 154.0 nM, respectively. PROTAC MPS1 degrader 1 can be used for the research of acute myeloid leukemia. (Pink: ligand for target protein ; Black: linker ; Blue: ligand for E3 ligase.
| CAS | P1426179 |
|---|---|
| Storage | Store at -20°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | PROTAC MPS1 degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 ( Mps1 , TTK) , AURKA and AURKB , with DC 50 s of 42.0, 2.1 and 154.0 nM, respectively. PROTAC MPS1 degrader 1 can be used for the research of acute myeloid leukemia. (Pink: ligand for target protein ; Black: linker ; Blue: ligand for E3 ligase. |