GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.10 mM in DMSO
Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC 50 s of 1 nM for JAK2 and TYK2 , 5 nM for JAK3 , and 15 nM for JAK1 , while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.
Specifications
Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES
CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O
PubChem CID
5494425
Molecular Weight
309.34
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
1.Pengcheng Zhao, Shihu Liu, Wei Huang, Lei He, Jiao Li, Jiong Zhou, Jian Zhou. (2020) Influence of eugenol on algal growth, cell physiology of cyanobacteria Microcystis aeruginosa and its interaction with signaling molecules. CHEMOSPHERE, [PMID:32387731][10.1016/j.chemosphere.2020.126935]
2.Zheng Kong, Degang Zhao. (2016) Modulation of the Fragrance of Kam Sweet Rice by Jasmonic Acid and Abscisic Acid Might Involve the MYC2 and ABI5 Transcription Factors. JOURNAL OF FOOD BIOCHEMISTRY, 40 (5):(639-646). [PMID:][10.1111/jfbc.12243]
3.Kaili Duan, Shaozhe Qin, Fangling Cui, Liangyuan Zhao, Yongqing Huang, Jin-Rong Xu, Guanghui Wang. (2025) MeJA inhibits fungal growth and DON toxin production by interfering with the cAMP-PKA signaling pathway in the wheat scab fungus Fusarium graminearum. mBio, [PMID:39902906][10.1128/mbio.03151-24]
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Reviews
Customer Reviews
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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