≥96% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
R-10015 R-10015 is a potent, selective inhibitor of LIM domain kinase (LIMK) with IC50 of 38 nM for human LIMK1. R-10015 binds to the ATP-binding pocket and acts as a broad-spectrum antiviral compound for HIV infection.
Targets
hLIMK1 (Cell-free assay) 38 nM
| ALogP | 3.677 |
|---|---|
| HBD Count | 2 |
| Rotatable Bond | 4 |
| Pubchem Sid | 504773065 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504773065 |
| Canonical Smiles | COC(=O)C1=CC2=C(C=C1)N=C(N2)C3CCN(CC3)C4=NC=NC5=C4C(=CN5)Cl |
| IUPAC Name | methyl 2-[1-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]-3H-benzimidazole-5-carboxylate |
| InChIKey | MGRJCGXCUUCOQG-UHFFFAOYSA-N |
| INCHI | 1S/C20H19ClN6O2/c1-29-20(28)12-2-3-14-15(8-12)26-17(25-14)11-4-6-27(7-5-11)19-16-13(21)9-22-18(16)23-10-24-19/h2-3,8-11H,4-7H2,1H3,(H,25,26)(H,22,23,24) |
| PubChem CID | 129896912 |
| Molecular Weight | 410.86 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2214643 | Certificate of Analysis | Aug 13, 2025 | R413653 |
| K2214644 | Certificate of Analysis | Aug 13, 2025 | R413653 |
| K2214645 | Certificate of Analysis | Aug 13, 2025 | R413653 |
| K2214656 | Certificate of Analysis | Aug 13, 2025 | R413653 |
| K2214657 | Certificate of Analysis | Aug 13, 2025 | R413653 |
| Solubility | Solubility (25°C) In vitro DMSO: 82 mg/mL (199.58 mM); Ethanol: 10 mg/mL (24.33 mM); Water: ˂1 mg/mL |
|---|---|
| DMSO(mg / mL) Max Solubility | 82 |
| DMSO(mM) Max Solubility | 199.581365915397 |
| Water(mg / mL) Max Solubility | ˂1 |
| Molecular Weight | 410.900 g/mol |
| XLogP3 | 3.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 410.126 Da |
| Monoisotopic Mass | 410.126 Da |
| Topological Polar Surface Area | 99.800 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 604.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
