(R)-3-Hydroxybutanoic acid - ≥95% , CAS No.625-72-9

CAS: 625-72-9 Cat. No.: R304188 Molecular Weight: 104.1 EC Number: 210-909-6
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Synonyms
Q27075135 | (-)-beta-Hydroxybutyrate, D- | Hydantoin, 5-isobutyl-3-phenyl-2-thio- | 3-D-hydroxybutyric acid | (R)-(-)-3-Hydroxybutyric acid | (R)-(-)-beta-Hydroxybutyric acid | delta-3-hydroxybutyrate | (R)-3-Hydroxybutyric acid | (R)-β-Hydroxybutanoic Ac
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
250mg
R304188-250mg
3
$9.90
1g
R304188-1g
2
$11.90
5g
R304188-5g
2
$36.90
10g
R304188-10g
1
$56.90
25g
R304188-25g
2
$109.90
100g
R304188-100g
1
$309.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. Beta-hydroxybutyrate is a typical partial-degradation product of branched-chain amino acids (primarily valine) released from muscle for hepatic and renal gluconeogenesis.

Specifications

Synonyms
Q27075135 | (-)-beta-Hydroxybutyrate, D- | Hydantoin, 5-isobutyl-3-phenyl-2-thio- | 3-D-hydroxybutyric acid | (R)-(-)-3-Hydroxybutyric acid | (R)-(-)-beta-Hydroxybutyric acid | delta-3-hydroxybutyrate | (R)-3-Hydroxybutyric acid | (R)-β-Hydroxybutanoic Ac
Specifications & Purity
≥95%
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥95%
Names and Identifiers
Pubchem Sid504756102
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504756102
Canonical SmilesCC(CC(=O)O)O
IUPAC Name(3R)-3-hydroxybutanoic acid
InChIKeyWHBMMWSBFZVSSR-GSVOUGTGSA-N
INCHI1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1
Isomeric SMILES C[C@H](CC(=O)O)O
Molecular Weight 104.1
Reaxy-Rn 773861
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=773861&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassHydroxy acids and derivatives
SubclassBeta hydroxy acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentBeta hydroxy acids and derivatives
Alternative Parents Short-chain hydroxy acids and derivatives  Fatty acids and conjugates  Secondary alcohols  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic acyclic compounds
Substituents Short-chain hydroxy acid - Beta-hydroxy acid - Fatty acid - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic acyclic compound
DescriptionThis compound belongs to the class of organic compounds known as beta hydroxy acids and derivatives. These are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
External Descriptors Hydroxy fatty acids
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
HCAR2 Tclin Hydroxycarboxylic acid receptor 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a20 Solute carrier family 22 member 20 (86 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

35 results found

Lot NumberCertificate TypeDateItem
L2511643Certificate of AnalysisNov 29, 2025 R304188
D2620053Certificate of AnalysisNov 29, 2025 R304188
L2511639Certificate of AnalysisNov 29, 2025 R304188
L2511644Certificate of AnalysisNov 29, 2025 R304188
F2609037Certificate of AnalysisNov 29, 2025 R304188
L2511645Certificate of AnalysisNov 29, 2025 R304188
L2511654Certificate of AnalysisNov 29, 2025 R304188
L2511656Certificate of AnalysisNov 29, 2025 R304188
F2214196Certificate of AnalysisApr 02, 2025 R304188
F2214035Certificate of AnalysisApr 02, 2025 R304188
K2425527Certificate of AnalysisNov 12, 2024 R304188
K2425486Certificate of AnalysisNov 12, 2024 R304188
K2425485Certificate of AnalysisNov 12, 2024 R304188
K2425484Certificate of AnalysisNov 12, 2024 R304188
K2425483Certificate of AnalysisNov 12, 2024 R304188
K2425482Certificate of AnalysisNov 12, 2024 R304188
J2409840Certificate of AnalysisSep 21, 2024 R304188
J2409818Certificate of AnalysisSep 21, 2024 R304188
J2409811Certificate of AnalysisSep 21, 2024 R304188
J2409794Certificate of AnalysisSep 21, 2024 R304188
J2409819Certificate of AnalysisSep 21, 2024 R304188
G2429482Certificate of AnalysisJul 09, 2024 R304188
G2429481Certificate of AnalysisJul 09, 2024 R304188
G2429480Certificate of AnalysisJul 09, 2024 R304188
G2429479Certificate of AnalysisJul 09, 2024 R304188
G2429391Certificate of AnalysisJul 09, 2024 R304188
J2530618Certificate of AnalysisMar 29, 2024 R304188
K2307260Certificate of AnalysisOct 21, 2023 R304188
K2307288Certificate of AnalysisOct 21, 2023 R304188
K2307291Certificate of AnalysisOct 21, 2023 R304188
K2307297Certificate of AnalysisOct 21, 2023 R304188
E2325086Certificate of AnalysisMay 30, 2022 R304188
F2214198Certificate of AnalysisMay 30, 2022 R304188
F2214199Certificate of AnalysisMay 30, 2022 R304188
J2310196Certificate of AnalysisMay 30, 2022 R304188

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Chemical and Physical Properties
SolubilitySolubility:H2O: 25 mg/mL (240.15 mM)
SensitivityHeat sensitive
Flash Point(°C)112 °C
Boil Point(°C)92 °C/0.08 mmHg
Melt Point(°C)43-50°C
Molecular Weight104.100 g/mol
XLogP3-0.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass104.047 Da
Monoisotopic Mass104.047 Da
Topological Polar Surface Area57.500 Ų
Heavy Atom Count7
Formal Charge0
Complexity69.300
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Jingling Guo, Pan Wang, Yifan Cui, Xiaosong Hu, Fang Chen, Chen Ma.  (2022)  Alleviation Effects of Microbial Metabolites from Resveratrol on Non-Alcoholic Fatty Liver Disease.  Foods,  12  (1): (94).  [PMID:36613310] [10.3390/foods12010094]
2. Guojia Yu, Xinjian Chen, Lichao He, Xiangrong Li, Zhiyong Zhou, Zhongqi Ren.  (2021)  Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids.  CRYSTENGCOMM,  23  (27): (4871-4878).  [PMID:] [10.1039/D1CE00551K]
3. Waqar Uddin, Gang Hu, Xuanxuan Sun, Hui Zhang, Yegui Wang, Lin Hu.  (2017)  Identification of two aromatic isomers between 3- and 4-hydroxy benzoic acid by their perturbation on the potential oscillations of a Belousov-Zhabotinsky system.  Arabian Journal of Chemistry,      [PMID:] [10.1016/j.arabjc.2017.09.010]
4. Waqar Uddin, Gang Hu, Lin Hu, Yanyang Hu, Zhaohui Fang, Rooh Ullah, Xuanxuan Sun, Yu Zhang, Jimei Song.  (2017)  Identification of two aromatic isomers between 2- and 3-hydroxy benzoic acid by using a Briggs-Rauscher oscillator.  JOURNAL OF ELECTROANALYTICAL CHEMISTRY,      [PMID:] [10.1016/j.jelechem.2017.09.014]
5. Chencheng Dai, Yiwei Cao, Yiran Xu, Moyuan Li, Guangquan Liu, Sujuan Xu, Nuo Ye, Changxiang Shi, Tiantian Fan, Pengfei Xu, Xuemei Jia.  (2026)  Serum metabolic fingerprinting for diagnosis and therapeutic applications of ovarian endometriosis.  iScience,  29  (3):   [PMID:41743236] [10.1016/j.isci.2026.114887]
6. Shasha Yang, Xiaofei Yu, Keming Wang, Maofa Yang, Xuli Zhu, Huizi Wu, Hanjie Guan, Chunyang Huang, Xiang Yang.  (2026)  Sex Pheromones From Linyphia triangularis (Araneae: Linyphiidae) and Aphidoletes aphidimyza (Diptera: Cecidomyiidae) Are Promising Attractants for Aphidoletes aphidimyza (Diptera: Cecidomyiidae).  JOURNAL OF APPLIED ENTOMOLOGY,      [PMID:] [10.1111/jen.70086]
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