R-(-)-alpha-Methylhistamine dihydrobromide - Moligand™, ≥99% , Agonist of H 3 receptor;Agonist of H 4 receptor, CAS No.75614-87-8, Agonist of H 3 receptor;Agonist of H 4 receptor
R-(-)-alpha-Methylhistamine dihydrobromide - Moligand™, ≥99% , Agonist of H 3 receptor;Agonist of H 4 receptor, CAS No.75614-87-8, Agonist of H 3 receptor;Agonist of H 4 receptor
GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥99%
Highly potent, selective H 3 receptor agonist (K d = 50 nM). Induces H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Inhibits H 3 -mediated histamine synthesis and release in the CNS. Active in vivo.
Storage
Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of H 3 receptor;Agonist of H 4 receptor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors
imidazoles - aralkylamino compound
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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