GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.High Performance?High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥90%(SDS-PAGE)See COA
Expression System
HEK293
Accession #
P24593
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<0.1 EU/μg
Bioactivity
1、Measured by its ability to inhibit the biological activity of IGF-I on MCF‑7 human breast cancer cells. The ED50 for this effect is 73.91 ng/mL in the presence of 2 ng/mL Recombinant Human IGF-1 Protein (rp147252). 2、Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFBP-5 Protein (rp167866) at 1 μg/mL can bind Human IGF-1 Protein, the ED50 for this effect is 88.81 ng/mL.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,High Performance,His-Tag,≥90%(SDS-PAGE),See COA ActiBioPure™,Animal Free,Bioactive,Carrier Free,High Performance,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications
Product Name
Recombinant Human IGFBP-5 Protein
Synonyms
IBP-5 | IGF-binding protein 5 | IGFBP5 | IGFBP-5 | insulin-like growth factor binding protein 5 | insulin-like growth factor-binding protein 5
Grade
ActiBioPure™, Animal Free, Bioactive, Carrier Free, High Performance, His Tag
Specifications & Purity
Animal Free, Carrier Free, Bioactive, ActiBioPure™, High Performance, His-Tag, ≥90%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms
Multifunctional protein that plays a critical role in regulating the availability of IGFs to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Incr
Bioactivity
1、Measured by its ability to inhibit the biological activity of IGF-I on MCF‑7 human breast cancer cells. The ED50 for this effect is 73.91 ng/mL in the presence of 2 ng/mL Recombinant Human IGF-1 Protein (rp147252). 2、Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFBP-5 Protein (rp167866) at 1 μg/mL can bind Human IGF-1 Protein, the ED50 for this effect is 88.81 ng/mL.
30 - 37 kDa, under reducing conditions; 30 - 37 kDa, under non-reducing conditions.
Molecule Type
Protein
Storage and Shipping
Concentration
See COA
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~-80℃ long term (1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Human IGFBP-5 Protein (rp167866) - SDS-PAGE 2 μg/lane of Recombinant Human IGFBP-5 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 30 - 37 kDa.
Recombinant Human IGFBP-5 Protein (rp167866) - Protein Bioactivity Measured by its ability to inhibit the biological activity of IGF-I on MCF‑7 human breast cancer cells. The ED50 for this effect is 73.91 ng/mL in the presence of 2 ng/mL Recombinant Human IGF-1 Protein (rp147252).
Recombinant Human IGFBP-5 Protein (rp167866) - Protein Bioactivity Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFBP-5 Protein (rp167866) at 1 μg/mL can bind Human IGF-1 Protein, the ED50 for this effect is 88.81 ng/mL.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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