Recombinant Human Type III Collagen, CAS No.9007-34-5

CAS: 9007-34-5 Cat. No.: rp335221 EC Number: 232-697-4

GRADE & PURITY Animal Free, Carrier Free, Recombinant, ≥90%(SDS-PAGE), expressed in Nicotiana benthamiana

Accession #

P02461

Expression system

Nicotiana benthamiana

Overview

Through a plant expression platform and purification process, it overcomes the limitations of traditional collagen, such as low homology, high batch-to-batch variation, and the risk of animal-derived contamination. It achieves up to 100% amino acid homology with human collagen and exhibits a structure highly similar to that of human collagen, representing an approximately 1.3-fold improvement over traditional collagen, with low immunogenicity. Batch-to-batch consistency is enhanced by more than 10 times. Meanwhile, the irritancy of this ingredient is significantly reduced. It also inhibits free radical oxidative damage, promotes cell proliferation and migration, enhances the expression of hyaluronic acid and filaggrin, and improves skin barrier repair as well as anti-wrinkle and firming effects. 

This product is typically a white or off-white foamy/spongy loose lyophilizate. The molecule adopts a loose helical structure; upon reconstitution, the resulting solution or gel exhibits good spreadability and flexibility, along with excellent water retention capacity and emulsion stability. 

Solubility characteristics: soluble under neutral low-salt conditions, and dissolves more rapidly and completely at low pH.

Recommended applications: High-end medical devices (e.g., wound dressings, fillers), functional skin care products (repairing, anti-aging), and pet products.

Specifications

Product Name

Recombinant Human Type III Collagen, CAS No.9007-34-5

Synonyms

alpha1 (III) collagen | alpha-1 type III collagen | COL3A1 | Collagen 3 | collagen alpha-1(III) chain | Collagen III alpha 1 | collagen, fetal | collagen type III alpha 1 | Collagen-3 | collagenIII | Collagen-III | EDS4A | EDSVASC | Ehlers-Danlos syndro.

Grade

Animal Free, Carrier Free, Recombinant

Specifications & Purity

Animal Free, Carrier Free, Recombinant, ≥90%(SDS-PAGE), expressed in Nicotiana benthamiana

Biochemical and Physiological Mechanisms

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the

Accession #

P02461

SDS-PAGE

15-35 kDa

CAS

9007-34-5

Molecule Type

Protein

Storage and Shipping

Concentration

expressed in Nicotiana benthamiana

Reconstitution

Reconstitute in sterile water or buffer.

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Stability And Storage

Store at -20℃ long term (12 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated.

References

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