Ro 31-9790 - ≥98% , CAS No.145337-55-9

CAS: 145337-55-9 Cat. No.: R648357 Molecular Weight: 315.41

GRADE & PURITY ≥98%

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Overview

Ro 31-9790 is a synthetic metalloproteinase ( MMP ) inhibitor.

In Vitro

Ro 31-9790 inhibits L-selectin shedding from mouse and human lymphocytes, Jurkat T cells, and human monocytes with an IC 50 of 0.3-0.4 μM on these cell types. The IC 50 values obtained for Ro 31-9790 are 4.82 ± 0.75 μM, 1.16 ± 0.27 μM, 0.70 ± 0.06 μM, 4.47± 1.27 μM and 0.38 ± 0.05 μM for mouse lymphocyte L-selectin shedding, Jurkat L-selectin shedding, human lymphocyte L-selectin shedding, human monocyte L-selectin shedding and human monocyte TNF-α shedding. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:MMP

Specifications

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Ro 31-9790 is a synthetic metalloproteinase ( MMP ) inhibitor.

Storage

Store at 2-8°C, Protected from light, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: O=C(N[C@H](C(NC)=O)C(C)(C)C)[C@H](CC(C)C)CC(NO)=O
• Molecular Weight: 315.41

Chemical and Physical Properties

• Solubility: DMSO : 50 mg/mL (158.52 mM; ultrasonic and warming and heat to 70°C)