RY796 - Moligand™ , Gating inhibitor of K v2.1;Gating inhibitor of K v2.2, CAS No.R613349, Gating inhibitor of K v2.1;Gating inhibitor of K v2.2

CAS: R613349 Cat. No.: R613349 PubChem CID: 71719898

GRADE & PURITY Moligand™

Synonyms

RY 796;RY-796

Storage

Room temperature

Specifications

Synonyms

RY 796;RY-796

Specifications & Purity

Moligand™

Storage

Room temperature

Grade

Moligand™

Action Type

GATING INHIBITOR

Mechanism of action

Gating inhibitor of K v2.1;Gating inhibitor of K v2.2

Names and Identifiers

• Canonical Smiles: O=C(C(C)C)Nc1ccc(c(c1)C(=O)N[C@H](c1ccccc1)C)N(C)C
• IUPAC Name: 2-(dimethylamino)-5-(2-methylpropanoylamino)-N-[(1S)-1-phenylethyl]benzamide
• InChIKey: LDXZFQWWXMRMAS-HNNXBMFYSA-N
• INCHI: 1S/C21H27N3O2/c1-14(2)20(25)23-17-11-12-19(24(4)5)18(13-17)21(26)22-15(3)16-9-7-6-8-10-16/h6-15H,1-5H3,(H,22,26)(H,23,25)/t15-/m0/s1
• Isomeric SMILES: C[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C=CC(=C2)NC(=O)C(C)C)N(C)C
• PubChem CID: 71719898

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives
        • Level5 Benzamides
          • Level6 N-benzylbenzamides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Benzamides
• Direct Parent: N-benzylbenzamides
• Alternative Parents: Acylaminobenzoic acid and derivatives Anthranilamides 2-aminobenzamides Anilides N-arylamides Dialkylarylamines Benzoyl derivatives Aniline and substituted anilines Vinylogous amides Secondary carboxylic acid amides Amino acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: N-benzylbenzamide - Acylaminobenzoic acid or derivatives - Aminobenzamide - Anthranilamide - Aminobenzoic acid or derivatives - 2-aminobenzamide - Anilide - Benzoyl - Tertiary aliphatic/aromatic amine - Aniline or substituted anilines - Dialkylarylamine - N-arylamide - Vinylogous amide - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Tertiary amine - Carboxylic acid derivative - Organonitrogen compound - Amine - Carbonyl group - Organic oxide - Organooxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as n-benzylbenzamides. These are compounds containing a benzamide moiety that is N-linked to a benzyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

KCNB1 Tclin Potassium voltage-gated channel subfamily B member 1 (1 Activities)

Discover Target: KCNB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNB2 Tclin Potassium voltage-gated channel subfamily B member 2 (2 Activities)

Discover Target: KCNB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action